Molecule-surface recognition and supramolecular interactions
Influence of molecule-surface and molecule-molecule interactions on two-dimensional patterns formed by functionalised aromatic molecules
... and molecule–surface ...the molecule–surface and molecule–molecule interactions are systematically mapped out to develop understanding of their phase ...
24
Supramolecular interactions in the solid state
... in supramolecular terms, the latter consti- tutes an isomerization ...cular interactions. Within a crystal, every displacement of a molecule from its equilibrium conformation, position and ...
16
Obtaining control of cell surface functionalizations via Pre-targeting and Supramolecular host guest interactions
... www.nature.com/scientificreports/ receptor (GFP), Cy3 1.5 CD 72 PIBMA 389 (Cy3), and Cy5-Ad 2 (Cy5) (Fig. 4b). Use of Cy5 (8) alone did not result in staining (Supplementary Fig. S20). Moreover, experiments where Cy5-Ad ...
11
Modelling molecule-surface interactions-an automated quantum-classical approach using a genetic algorithm
... solid interfacial potentials. However, the lack of experimental data describing the interfacial region turns the parametrisation of such surface potentials into a non-trivial problem. To date, quantum-classical ...
7
Investigation of the interactions in RNA recognition motif-RNA complexes: small molecule inhibitors and kinetics of dissociation
... 2.2.3 Compound screening. We chose to utilize the Chembridge library (32,000 compounds) and NCI library (10,560 compounds) for high throughput screening because they contain compounds with a high degree of molecular ...
141
Investigating Particle-Particle and Molecule-Surface Interactions Using Three-Dimensional Super Localization and Tracking Method.
... Particle-particle Interactions The samples were made in chambers with 100μm ...particle interactions can be ...the surface and attracted by each ...
77
A supramolecular chain of dimeric Dy single molecule magnets decorated with azobenzene ligands
... lanthanide ions because their photoconversion induces both an electrostatic change in the ion surrounding and a strong molecular motion in the crystal packing that can in some cases, goes up to single-crystal to ...
11
IGCR1 is a novel cell-surface molecule
... Cellular Adhesion Molecules and Angiogenesis Cell adhesion molecules (CAMs) are cell-surface receptor proteins that allow cells to adhere to each other and sense their surroundings (Cavallaro,and Christofori. ...
48
Small molecule inhibitors of protein-protein interactions
... druggability, based on structural and physicochemical features of the binding sites. The parameters of this model provide insight in what properties are important in molecular recognition. However, because only 23 ...
227
Small Molecule Inhibitors of Protein-Protein Interactions
... of surface area in the acceptor protein, have in ...the recognition process anchors target well-defined “druggable” ...small molecule inhibitors using fast and efficient MCR ...p53 ...
229
Exploring a naturally tailored small molecule for stretchable, self-healing, and adhesive supramolecular polymers
... 37. B. Coupe, M. E. Evangelista, R. M. Yeung, W. Chen, Surface modification of poly(tetrafluoroethylene-co-hexafluoropropylene) by adsorption of functional polymers. Langmuir 17, 1956–1960 (2001). Acknowledgments: ...
9
Exploiting the CH-π interactions in supramolecular hydrogels of aromatic carbohydrate amphiphiles
... p interactions. This was due to the interest in CH- p interactions, the structural and stereo-diversity accessible and the potential applications for biospecific recognition of carbohydrate-based ...
8
Evaluation and Development of Quantum Chemical Methodologies for Noncovalent Interactions and Supramolecular Thermochemistry
... Complex 11 belongs to the ones which have a fullerene as guest molecule. For these type of large, electronically delocalized systems a partial breakdown of pairwise dispersion interaction schemes has been observed ...
291
Discovery of Small Molecule Inhibitors of Protein-Protein Interactions
... PPIs are often mediated by only a few key amino acid side chains and the terms “hot spot” and “anchor” have been introduced for such locally constrained areas and amino acids on the surface of interacting ...
292
Investigation of the temperature dependence of single molecule biomolecular interactions
... multiple interactions were observed, in addition to force curves having no adhesion ...sample surface were prepared with a paucity of reactive sites, as small amount of ligand (biotin)-receptor ...
107
NEW MESOPOROUS MATERIALS WITH SURFACE SUPRAMOLECULAR CENTRES FOR METHYL RED SORPTION
... silica surface (Scheme 3, Figure ...of surface cyclic oligosaccharide groups, which are able to form inclusion complexes with protolytic forms of the ...of interactions between MR and functional ...
15
Theoretical and Experimental Investigations of Anion-π Interactions in Inorganic and Biological Supramolecular Architectures
... 11 theoretical model of the electronic contributions to the anion-π interaction has been developed by Wheeler and Houk. In this model, repulsion between the anion and π-orbitals is overcome by the ion- dipole interaction ...
307
Single-molecule Surface Studies of Fibrinogen and DNA on Semiconductors
... hydrophobic interactions, electrostatic interactions, surface geometry and steric considerations, and temperature effects 4,33 ...hydrophobic interactions. It was investigated that on a ...
191
Protein-protein interactions as targets for small-molecule therapeutics in cancer
... protein interactions that mediate many important biological processes is an emerging and challenging area in drug ...small molecule to bind to a protein–protein interface and subsequently inhibit the ...
14
The chemical interactions of the template molecule are primarily dependent on the choice of polymer
... The resonant structure of DMF is more likely to interact with the nitro group of 4-nitrotoluene and the OH in the phenol group of PVP as compared to MEK, and may impair the widespread formation of the polymer-template ...
9