Monocyte subsets
Overexpression of TLR2 and TLR9 on monocyte subsets of active rheumatoid arthritis patients contributes to enhance responsiveness to TLR agonists
... For intracellular cytokine staining (ICCS), peripheral blood mononuclear cells (PBMC) from healthy volun- teers and RA patients were isolated using Ficoll density gradient. After an overnight resting, cells were washed ...
14
Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability.
... non-classical monocyte subsets that each express characteristic patterns of cell surface CD16 and CD14; each subset also has specific functional properties, but the mechanisms underlying many of their ...
13
Differential expression of CCR2 and CX3CR1 on CD16+ monocyte subsets is associated with asthma severity
... on monocyte subsets from mild asthmatic patients (n = 22), moderate asthmatic patients (n = 32) and severe asthmatic patients (n = 22) compared to healthy control (n = ...Each monocyte subset is ...
11
Original Article Changes of monocyte subsets in patients with acute coronary syndrome and correlation with myocardial injury markers
... The monocyte-platelet aggregates were significant- ly higher in patients with acute heart failure than those in chronic heart failure and HS, but no significant difference in coronary artery dis- ease ...of ...
6
Monocyte subsets have distinct patterns of tetraspanin expression and different capacities to form multinucleate giant cells
... between subsets but the lack of a clear pattern suggests that this is not the primary driver of the variation between monocyte ...the subsets do show remarkably diferent cytokine proiles during ...
17
Human T Cell Leukemia Virus Type 1 Infection of the Three Monocyte Subsets Contributes to Viral Burden in Humans
... In contrast to the findings of Amorim et al. (71), we observed no differences in the frequency of intermediate monocytes in HTLV-1-infected and uninfected individuals. Possible explana- tions for the difference in subset ...
13
Counts of bovine monocyte subsets prior to calving are predictive for postpartum occurrence of mastitis and metritis
... bovine monocyte subsets in vivo remain unclear, it has been shown that cows that develop infectious disease post- partum also have an altered monocyte ...that monocyte phagocytic capacity was ...
11
Correlation analysis of monocyte subsets and insulin resistance considering fetuin-A involvement in patients with type 2 diabetes
... of monocyte subsets to macrophage polar- ity, M1 or ...circulating monocyte TLR4 activity in humans ...of monocyte subsets in circulation might not always be parallel to the ...
7
Detection and Differentiation of Different Monocyte Subsets: Optimalization of a Multiparameter Flowcytometric Assay
... Monocytes are mononuclear and characterized by a kidney-shaped nucleus. As the main component of the innate immune system, they are responsible for the clearance of bacterial, viral and fungal infections, mainly by the ...
11
CD14hiCD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so
... USA). Monocyte subsets were identified by staining with anti CD14 APC (M5E2, BD Biosciences) and CD16 FITC (3G8, BD Biosciences), and phagocytosis was determined by measuring EtBr fluorescence in the PE ...
14
Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets
... Peripheral blood cultures with sera from SLE patients and HC with and without co-stimulation with TLR4 ligand - LPS To assess the effect of SLE sera upon TNF-α production by normal peripheral blood monocyte ...
9
CD16+ Monocyte Subsets in Patients with Total Joint Arthroplasty
... samples were stained with fluorescein isothiocyanate (FITC)-conjugated anti-CD14 anti- body and phycoerythrin (PE)-conjugated anti-CD16 antibody, followed by lysis of eryt- hrocytes. Cells were collected on a Becton ...
17
Association between lymphocyte and monocyte subsets and cognition in children with HIV
... It must be acknowledged that the peripheral blood B cell compartment contains several distinct B cell types, e.g., immature/transitional (CD10 + , CD27 - , activated/ mature (CD21 lo CD10 - ), and resting memory (CD21 hi ...
5
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques
... Monocytes participate critically in atherosclerosis. There are 2 major subsets expressing different chemokine receptor patterns: CCR2 + CX3CR1 + Ly-6C hi and CCR2 – CX3CR1 ++ Ly- 6C lo monocytes. Both C-C motif ...
11
Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases
... different monocyte subsets in the pathogenesis of stroke remain ...reduced monocyte and neutrophil infiltration ...+ monocyte depletion by clondronate liposome or by bone marrow ...
9
Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis
... Altered monocyte function, including diminished HLA-DR expression and impaired proinflammatory cytokine response, was previously reported in patients with sepsis, severe trauma and major ...all monocyte and ...
12
Differential expression and predictive value of monocyte scavenger receptor CD163 in populations with different tuberculosis infection statuses
... three monocyte subsets represent different stages of macrophage differentiation and play different roles in ...total subsets; they differentiate into pro- inflammatory M1 macrophages (classical ...
12
PubMedCentral-PMC5094498.pdf
... peripheral monocyte count of > 400 cells/ l L exhibited a dichotomy of CD14, CD16 expression on monocytes— CD14 expression was high and CD16 expression was low, when compared to dogs with monocyte counts ...
12
Telomere attrition in heart failure: a flow FISH longitudinal analysis of circulating monocytes
... mean monocyte TL (11.1 ± 3.3 vs. 8.3 ± 2.1, p < 0.001). Mean monocyte TL change was –22% ± 20 ...2). Monocyte TL reduction occurred in ...(51.9%) monocyte TL reduction was ≥ − ...the ...
8
Regulation of peripheral classical and non classical monocytes on infliximab treatment in patients with rheumatoid arthritis and ankylosing spondylitis
... monocytes have been found to produce large amounts of TNF 5 but are not able to differen- tiate into osteoclasts, 6 whereas classical mono- cytes (CD14+CD16 − ) are mainly producers of interleukin-10 6 and are able to ...
5