monozygotic twin pairs
A Genome-Wide Association Study of Monozygotic Twin-Pairs Suggests a Locus Related to Variability of Serum High-Density Lipoprotein Cholesterol
... on monozygotic twin-pairs offers a route to discovery of gene– environment interactions through testing for variability loci associated with sensitivity to individual environ- ...1,720 ...
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Dietary Intake at 9 Years and Subsequent Body Mass Index in Adolescent Boys and Girls: A Study of Monozygotic Twin Pairs
... adolescent monozygotic boy and girl twin ...BMI-discordant monozygotic twin pairs were also identified to analyze the dietary constituents that may have generated the ...
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Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs
... female monozygotic twin- pairs discordant for cancers of the solid ...MZ twin-pairs ...co- twin (Fig. 1b). The remaining MZ twin-pairs were clus- tered by array, ...
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Leukocyte and Skeletal Muscle Telomere Length and Body Composition in Monozygotic Twin Pairs Discordant for Long-term Hormone Replacement Therapy
... Estrogen-based hormone replacement therapy (HRT) may be associated with deceleration of cellular ag- ing. We investigated whether long-term HRT has effects on leukocyte (LTL) or mean and minimum skeletal muscle telomere ...
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Aging as Accelerated Accumulation of Somatic Variants: Whole-Genome Sequencing of Centenarian and Middle-Aged Monozygotic Twin Pairs
... MZ twin pairs of 40 and 100 years. The 40-year-old MZ twin pair is participating in the Nether- lands Twin Registry (NTR co-twins) and the centenarian MZ twin pair in the Leiden ...
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Large Autosomal Copy-Number Differences within Unselected Monozygotic Twin Pairs are Rare
... The one CNV with strong evidence for a discordance in an MZ pair was a 130 kb duplication between 78,333,027– 78,460,944 bp on chromosome 5. This duplication demon- strated the expected four bands in the B allele ...
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DNA methylation differences in monozygotic twin pairs discordant for schizophrenia identifies psychosis related genes and networks
... on monozygotic twins received ethics ap- proval by the University of Western Ontario’s Commit- tee on research involving human ...the twin pair were present and gave consent at the same time (the normal ...
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Epigenetic supersimilarity of monozygotic twin pairs
... than pairs of unrelated individuals, probe-specific MSEs were normal- ized relative to randomized pairs (RZ), simulating pair- wise MSE within the general ...MZ twin pairs show ...
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Copy Number Variation Distribution in Six Monozygotic Twin Pairs Discordant for Schizophrenia
... six pairs of monozygotic twins discordant (MZD) for schizophrenia and assessed the CNV differences between twin ...utilizing monozygotic twins have associated CNV and methylation differences ...
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X Chromosome Inactivation Patterns Correlate with Fetal-Placental Anatomy in Monozygotic Twin Pairs: Implications for Immune Relatedness and Concordance for Autoimmunity
... We therefore reasoned that X chromo- some inactivation patterns in peripheral blood should be more similar in twins with a shared placental blood supply (monochorionic twins), compared w[r] ...
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CNV Analysis in Monozygotic Twin Pairs Discordant for Urorectal Malformations
... in monozygotic (MZ) twin ...MZ twin pairs with ARM or the BEEC; knowledge of such CNVs might help to identify additional chromosomal regions involved in the development of these ...MZ ...
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Heritability of Apnea of Prematurity: A Retrospective Twin Study
... for monozygotic, DZu, and TWa twin groups are presented in Table ...56 monozygotic twin pairs (112 infants), 161 DZu twin pairs (322 infants), of whom 39 were same- gender ...
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Heritability in genetic heart disease: the role of genetic background
... collected monozygotic twin pairs with dilated cardio- myopathy (DCM), hypertrophic cardiomyopathy (HCM) or long QT syndrome type 1, 2 or 3 (LQTS) from fami- lies with a high suspicion of familial ...
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Brain Activation During Response Interference in Twins Discordant or Concordant for Obsessive Compulsive Symptoms
... within monozygotic twin pairs discor- dant for obsessive compulsive symptoms and between groups of pairs scoring very low or very high on obsessive compulsive symptoms, in order to examine the ...
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Does chronic smoking affect induced-exercise catecholamine release?
... Decreased Beta-Adrenergic Receptor Density and Catecholamine Response in Male Cigarette Smokers A Study of Monozygotic Twin Pairs Discordant for Smoking. Zouhal, H., Jacob, C., Delam[r] ...
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Are the brains of monozygotic twins similar? A three dimensional MR study
... in twin pairs; however, quantitative studies in five and 10 monozygotic twin pairs were performed by another team and published in two separate reports, respectively (6, ...five ...
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Case Report of Multiple Valve Disease Found in Triplets
... the monozygotic twin pair was early stage ...in twin B and non-coronary aortic cusp in twin ...in twin A was structurally and functionally ...
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Statistical Analyses of Monozygotic and Dizygotic Twinning Rates
... Bulmer (1970) presented slightly different approximate variance formulae. He assumed that the numbers of SS and OS twin sets are Poisson distributed but ignored that the numbers of OS and SS twin sets are ...
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Genetic Inheritance in Non-Syndromic Infantile Esotropia
... male monozygotic twins with strabismus also presented the same clinical ...in monozygotic twins with unaffected parents and dizygotic sibling manifesting similar genetic pattern, reinforcing the genetic ...
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Pulmonary Capillaritis in Monozygotic Twin Boys
... Pulmonary hemorrhage can be classi fi ed as either proximal or distal (alveolar). Causes of proximal hemorrhage include infection, foreign body aspiration, pulmonary embolus, trauma, vascular malformation, and pulmonary ...
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