Morris water maze test
Morris water maze test on neuroprotective effects of ethanolic extract of oyster mushroom (Pleurotus ostreatus) against neurotoxicity of mercury chloride in albino rats (Rattus norvegicus)
... memory test (morris water maze test), this was conducted in order to know the extent of spatial memory impairments caused by mercury toxicity, and also to ascertain the neuroprotective ...
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Enzyme replacement therapy for murine mucopolysaccharidosis type VII leads to improvements in behavior and auditory function
... Mucopolysaccharidosis type VII (MPS VII; Sly syndrome) is one of a group of lysosomal storage diseases that share many clinical features, including mental retardation and hearing loss. Lysosomal storage in neurons of the ...
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Original Article Modulatory effects of GABA R on cognitive function of epileptic rats
... GABA B R selective agonist baclofen could pro- long escape latency and decrease number of crossings in target quadrant of epileptic rats in Morris water-maze test, demonstrating that baclofen ...
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Tanshinone I alleviates motor and cognitive impairments via suppressing oxidative stress in the neonatal rats after hypoxic-ischemic brain damage
... To further determine the therapeutic effects of TsI on HIBD, we treated the rats with TsI daily for 7 days and the first injection was carried out immediately after HIBD. Four weeks after HIBD, the Morris ...
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Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze
... the Morris water maze test, and the dif- ferences in the freezing scores from the contextual fear conditioning ...the Morris water maze ...t test were used to ...
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Terminalia chebula extract prevents scopolamine induced amnesia via cholinergic modulation and anti oxidative effects in mice
... Scopolamine is a muscarinic ACh receptor antagonist that can cause learning and memory deficits by disrupt- ing cholinergic neurotransmission; this compound has been used to induce amnesia in experimental murine models ...
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Bis(9) (−) Meptazinol, a novel dual binding AChE inhibitor, rescues cognitive deficits and pathological changes in APP/PS1 transgenic mice
... weeks. Morris water maze, nest-building and novel object recognition were used to examine learning and memory ...the Morris water maze test, nest-building test and ...
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Effects of acupuncture on vascular dementia (VD) animal models: a systematic review and meta analysis
... Sixteen of the included studies used different subtests of the Morris water maze test; all the studies met the inclusion criteria by using escape latency as outcome data, while two studi[r] ...
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Rg3 enriched ginseng extract ameliorates scopolamine induced learning deficits in mice
... Ginsenoside Rg3 is not naturally present in Panax gin- seng [13] and is generated by the loss of the glucose group linked with the C-20 of ginsenoside Rc, Rd, Rb1, or Rb2 when ginseng roots are heated to a high ...
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Original Article High ω-3/ω-6 ratio diet could alleviate blood-brain barrier dysfunction in rat model with traumatic brain injury
... Abstract: Objectives: Polyunsaturated fatty acids (PUFAs) have functional activity in many aspects, including brain trauma. Diets with different ratios of ω-3/ω-6 were applied to investigate the protective effect on ...
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Neuroprotective effect of nicotine and simvastatin on cerebral ischemia induced cognitive impairment
... Cerebral ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. This vascular obstruction and the subsequent decrease in the cerebral blood flow results in immediate drop ...
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L THEANINE SHOWING THE NEUROPROTECTIVE ACTIVITY AGAINST LIPOPOLYSACCHARIDE INDUCED NEUROINFLAMMATION IN MICE MODEL
... Neuroinflammation is associated with a number of neurodegenerative diseases such as Alzheimer’s disease. It is reported that lipopolysaccharide (LPS) can induce neuroinflammation and cognitive impairment. L-Theanine is ...
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THE EFFECT OF MINOCYCLINE ON OXIDATIVE STRESS AND MEMORY DEFICITS IN AGED RATS
... Morris water maze test: Aged rodents show impairments in learning and memory, especially on tests requiring the use of spatial orientation to escape from stressful ...a Morris ...
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Orientation of lizards in a Morris water maze: roles of the sun compass and the parietal eye
... a Morris water- maze can be used to explore compass orientation mechanisms of ...a Morris water-maze onto a hidden goal, positioned at the periphery of the maze in a given ...
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Oxidation of Methionine 77 in Calmodulin Alters Mouse Development and Behavior
... the Morris water maze and associative ...stress test results were also the same for mutant and wild type ...field test, the mutant mice explored more than controls and exhibited reduced ...
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Effect of Grape Seeds Ethanolic Extract on Spatial Memory in Mice
... Grape (Vitis vinifera) is a member of vitaceae family. The seeds are rich in polyphenols and phenolic acids that are not only safe to be consumed, but also recognized to produce several and meaningful health benefits. We ...
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The Effects of Soy Extract on Spatial Learning and Memory Damage Induced by Global Ischemia in Ovariectomised Rats
... the Morris water maze task impairments due to cerebral ischemia in ovariectomised rats; however, there were no significant differences between the groups in the rotarod test ...
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EVALUATION OF LEARNING AND MEMORY ENHANCING ACTIVITY OF COCCINIA GRANDIS FRUITS IN RATS
... plus maze, Hebb’s William maze and Morris water maze were used in order to deduce the effectiveness of test ...amnesia. Test drugs also prevented diazepam induced memory ...
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Evaluation of Green Tea for Its Nootropic Activity
... Morris water maze consists of a large circular tank with a depth of 30cm, diameter ...with water added with milk in order to make it ...
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Effects of Citalopram on Learning and Memory in the Mouse and Rat
... Morris water maze. The Morris task was assessed in a water tank which consisted of a circular black tub (diameter 136 cm, depth 60 cm), filled with 25 cm of water at a ...
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