mouse embryogenesis
RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival
... MEF cells, p27 accumulation is associated with growth retardation and G1 arrest. Causal involvement of p27 accumulation in early death of RBX1-deficient embryos was clearly demonstrated by a rescue experiment in which ...
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Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis
... Previous studies have indicated that CBP and p300 proteins are mostly restricted to the nucleus of the cultured cells (Yaciuk and Moran, 1991; Chrivia et al., 1993; Eckner et al., 1994; Puri et al., 1997). Our studies ...
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Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domain
... The failure of the TF extracellular domain mutant to rescue mTF null embryos may be due to a lack of hTF expression at E9.5. We excluded this possibility by demonstrating hTF mRNA and protein expression by the mutED25 ...
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Basement membrane matrices in mouse embryogenesis, teratocarcinoma differentiation and in neuromuscular maturation
... Int J De' BioI 33 X1 !\9 (19X9) SI Basement membrane matrices in mouse embryogenesis, teratocarcinoma differentiation and in neuromuscular maturation ILMO LEIVO' and JORMA WARTIOVAARA Departments of P[.] ...
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Multiple Dlk1 splice variants are expressed during early mouse embryogenesis
... Given these facts, and the finding that DLK1 protein expression can be observed as early as E10 (Falix et al., 2013), we performed a study of Dlk1 expression during early mouse embryogenesis. Here, we ...
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Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis
... Wnt signaling is inhibited by several secreted antagonists: Dkk, Wise, Wif and Sfrp (Kawano and Kypta, 2003; Yamaguchi, 2001). Dickkopf (Dkk) and Wnt modulator in surface ectoderm (Wise) interact with co-receptor Lrp6, ...
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Growth factors and proto oncogenes in early mouse embryogenesis and tumorigenesis
... Int I De\ BioI 35 209 214 (1991) 209 Growth factors and proto oncogenes in early mouse embryogenesis and tumorigenesis KRESIMIR PAVELIC', NIVES PECINA SLAUS and RADAN SPAVENTI Ruder Boskovic Institute[.] ...
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The vertebrate phylotypic stage and an early bilaterian-related stage in mouse embryogenesis defined by genomic information
... has been the stage most conserved throughout the evolu- tion of vertebrates. Additionally, the peak of the amniote ancestor index at grouped stage 14 (Figure 2J) indicates that these stages express the smallest ratio of ...
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DNA binding dependent and independent functions of the Hand2 transcription factor during mouse embryogenesis
... A previously described 8 kb Hand2 genomic clone (from BamHI site to BamHI site) was used to generate the targeting vector. A 4.6-kb fragment was used as the 5 ⬘ long arm for homologous recombination, and a 2-kb fragment ...
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Expression of the Von Hippel-Lindau Tumor Suppressor Gene, VHL, in Human Fetal Kidney and During Mouse Embryogenesis
... Photomicrographs of VHL expression in the human fetal kidney and in murine embryogenesis.. (A and B) Expression of VHL in the human fetal kidney at 14 weeks gestation shown in toluidene [r] ...
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Identification of Ssm1b, a novel modifier of DNA methylation, and its expression during mouse embryogenesis
... An extensive analysis has been carried out with a target of Ssm1, the HRD transgene (supplementary material Fig. S1), which is a complex construct designed to study V(D)J recombination (Engler et al., 1991). When HRD is ...
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Different autonomous myogenic cell populations revealed by ablation of Myf5 expressing cells during mouse embryogenesis
... Myf5-independent muscle cell lineages, it was surprising to see that most of the early Myod1 expressing cells were killed during early somitogenesis. These results might be explained by the activation of the Myod1 gene ...
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Calpain 2 expression pattern and sub cellular localization during mouse embryogenesis
... ABSTRACT Regulation of migration and proliferation by calpain has been shown in various cell types; however, no data are available concerning calpain 2 (CAPN2) localization in embryonic tissues. Here, we report the ...
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Computational models for the dynamics of early mouse embryogenesis
... The mixed pattern of Epi and PrE cells observed at the E3.75- E4.0 stage is traditionally referred to as a salt and pepper pattern. The exact meaning of this expression to characterize the spatial arrangement of cells is ...
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Oct1 regulates trophoblast development during early mouse embryogenesis
... To assess the role that Oct1 plays during embryogenesis we inactivated the mouse Oct1 locus by homologous recombination in ES cells. At least four (multiple) alternatively spliced isoforms of Oct1 have been ...
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Macrophage clearance of cell death during mouse embryogenesis
... In both the developing footplate, where cell death in the remodelling interdigit is “catastrophic”, and in the kidney, where cell death is “trickle-like” and extended [r] ...
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Selective and Continuous Elimination of Mitochondria Microinjected Into Mouse Eggs From Spermatids, but Not From Liver Cells, Occurs Throughout Embryogenesis
... Kaneda, H., J.-I. Hayashi, S. Takahama, C. Taya, K. Fischer Lin- We are grateful to Drs. Michinori Kohara and Asao Katsume of dahl et al., 1995 Elimination of paternal mitochondrial DNA the Tokyo Metropolitan Institute ...
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In toto live imaging of mouse morphogenesis and new insights into neural tube closure
... Fig. 1. A novel in toto imaging system for mouse embryogenesis. (A) Four drops of vacuum grease are added to a 24 ⫻ 24 mm coverslip (i). A black filter paper is attached by pressing the filter onto the ...
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Detection of Two Viroids in the Tunisian Sweet Orange (Citrus sinensis L) Cv Maltese and Sanitation via Somatic Embryogenesis
... Explants used for induction of somatic embryogenesis consisted in style/stigma. For this reason, unopened flowers were collected from two infested trees (one viroїd/tree) and were surface sterilized by immersion ...
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Expression pattern of PAX3 and PAX6 genes during human embryogenesis
... Although highly resembling descriptions in experimental ani- mals, human PAX6 and PAX3 genes displayed small differences in their expression pattern when compared to other species. It refers to the weak expression of ...
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