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Mouse Heart

Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart

Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart

... adult mouse heart resulted in similar phenotypes, as did ablation of the FOG2 interaction with the transcription factor ...adult heart function and coronary ...

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Heat shock factor 2 is activated during mouse heart development

Heat shock factor 2 is activated during mouse heart development

... of mouse embryonic ...during mouse heart ...developing mouse heart at E11.5-12.5, a stage after which tubular heart has looped and chambers formed, and the myocardial walls are ...

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Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP

Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP

... the heart has been shown to be protective against the development of life-threatening ventricular arrhythmias, especially in the setting of MI (1, ...the mouse heart have demonstrated that the ...

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Cardiomyocyte-specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart

Cardiomyocyte-specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart

... reprogramming of cardiac fibroblasts into immature CM (Ieda et al., 2010; Qian et al., 2013). However, these approaches are not yet sufficiently advanced to enable correct integration of appropriately differentiated ...

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Characterization of a Carrier Mediated Transport System for Taurine in the Fetal Mouse Heart In Vitro

Characterization of a Carrier Mediated Transport System for Taurine in the Fetal Mouse Heart In Vitro

... aminopropane sulfonic acid, N-acetyltaurine, and isethionic acid. We conclude that a carrier-mediated transport system for taurine exists in the fetal mouse heart based on the demonstration of (a) ...

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Expression patterns and immunohistochemical localization of PITX2B transcription factor in the developing mouse heart

Expression patterns and immunohistochemical localization of PITX2B transcription factor in the developing mouse heart

... the heart (Franco et ...(LPM), heart and gut (Kitamura et ...in heart development gathered strength when, concurrently, Pitx2 specific null mice mutants (Pitx2abc -/- (Gage et ...the heart has ...

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Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart

... Animal procedures. To induce activity of the MerCreMer or the CreERT2 protein, mice were fed a diet containing 400 mg/kg tamox- ifen citrate (Envigo, TD.55125) or were treated with tamoxifen (Mil- liporeSigma, T5648) ...

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Maternal Diabetes as It Affects Extracellular Matrix Deposition in the Embryonic Mouse Heart

Maternal Diabetes as It Affects Extracellular Matrix Deposition in the Embryonic Mouse Heart

... and heart show an increase in the ECM, a condition known as fibrosis (Riva et ...of heart and kidney failure (Susic et ...the heart, fibrosis can cause stiffing of the ventricles ultimately causing ...

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RhoA protects the mouse heart against ischemia/reperfusion injury

RhoA protects the mouse heart against ischemia/reperfusion injury

... CA-RhoA mouse hearts from lines 7 and 25 at various times after Dox removal (off ...mm. Heart weight (HW) to body weight (BW) ratio and heart weight to tibial length (TL) ratio from WT, tTA, and ...

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Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart

Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart

... single intravenous injection of 50 μg/g [33, 34], and all mice received ketamine (120 mg/g; Ketanest-S, Pfizer, New York City, NY), midazolam (1.25 mg/g; Midazolam-ratiopharm, Ratiopharm, Ulm, BW, Germany), and fentanyl ...

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Cdc42 is an antihypertrophic molecular switch in the mouse heart

Cdc42 is an antihypertrophic molecular switch in the mouse heart

... the heart after pressure overload and in cultured cardiomyocytes by multiple ...a heart- specific deletion of Cdc42 developed greater cardiac hypertrophy at 2 and 8 weeks of stimulation and transitioned ...

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Journal of Applied Pharmaceutical Science

Journal of Applied Pharmaceutical Science

... Although the molluscicidal activity of crude dichloromethane extract of Millettia thonningii, known to be rich in alpinumisoflavones was attributed to its inhibition of isolated rat liver mitochondrial complex I ...

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cocaine analogs clarke pdf

cocaine analogs clarke pdf

... dosage as described by Luduena and Hoppe.16 In the mouse heart norepinephrine uptake inhibition experiments, aqueous solutions of DMI and cocaine hydrochlorides were used, as was an aque[r] ...

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The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy

The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy

... DOX-treated mouse heart fails to compensate for cardiac mtDNA depletion and mitochondrial protein oxidation, and intrinsic apop- tosis is initiated prior to LV dilation and ...

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GATA4 regulates Fgf16 to promote heart repair after injury

GATA4 regulates Fgf16 to promote heart repair after injury

... mammalian heart can regenerate during the neonatal stage, this endogenous regenerative capacity is lost with ...neonatal mouse heart regeneration. Using the neonatal mouse heart ...

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Postnatal ontogenesis of clock genes in mouse suprachiasmatic nucleus and heart

Postnatal ontogenesis of clock genes in mouse suprachiasmatic nucleus and heart

... the mouse SCN and ...the heart, for Bmal1, the timepoint of ZT12 which was the peak at P1 while developed to the trough at P3 and ...in mouse heart were roughly in same phase as found in ...

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GSK 3α directly regulates β adrenergic signaling and the response of the heart to hemodynamic stress in mice

GSK 3α directly regulates β adrenergic signaling and the response of the heart to hemodynamic stress in mice

... development, much remains unknown about the function of either GSK-3 isoform in the postnatal heart. Herein, we present what we believe to be the first studies defining the role of GSK-3a in the mouse ...

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Using the robust principal component analysis algorithm to remove RF spike artifacts from MR images

Using the robust principal component analysis algorithm to remove RF spike artifacts from MR images

... Furthermore, the mouse heart cine data was used to demonstrate the application of this algorithm to a single frame or static image (Fig. 4). The broad central k-space peak in the cine images makes this a ...

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Intracellular Function of Interleukin-1 Receptor Antagonist in Ischemic Cardiomyocytes

Intracellular Function of Interleukin-1 Receptor Antagonist in Ischemic Cardiomyocytes

... by mouse monoclonal anti-CD31/ PECAM-1 (Ab M89D3, gift of Dr ...on mouse heart tissue, followed by biotinylated anti-rabbit Ab and streptavidin- peroxidase VIP (purple) staining (Vector Labs, ...

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Regulation of cardiac microRNAs by serum response factor

Regulation of cardiac microRNAs by serum response factor

... level through accelerating the process of pri-miR-21 into precursor miR-21 (pre-miR-21) by the DROSHA com- plex [41]. Mir-21 is one of the miRNAs that was signifi- cantly increased in the SRF-Tg heart, but was ...

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