Mouse mammary epithelial cells
Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential
... BALB/c mammary glands (Figure ...normal mammary develop- ment [18,19]. However, studies using mouse models with complete germline deletion of ER (ER - / - ) have shown that ER was not required for ...
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REPLICATION OF CHROMATIN IN MOUSE MAMMARY EPITHELIAL CELLS GROWN IN VITRO
... The observation of two classes of labelled interphase nuclei, namely, cells with silver grains located in only euchromatic regions (Figures g,h) and cells with silver grains [r] ...
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Effect of substrate stiffness on early human embryonic stem cell differentiation
... involving mouse mammary epithelial cells that showed increased differentiation when grown on soft gel colla- gen substrates as opposed to Tissue Culture Plastic ...stem cells (MSCs) ...
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Isolation of a pathogenic clone of mouse mammary tumor virus.
... Finally, normal mouse mammary epithelial cells from endogenous and exogenous MMTV-free mice 8 could be efficiently infected in vitro by culture on irradiated XGRT39transfected LA7 cell f[r] ...
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Genes affected by mouse mammary tumor virus (MMTV) proviral insertions in mouse mammary tumors are deregulated or mutated in primary human mammary tumors.
... premalignant mammary lesions and their progression to malignancy and ...a mouse model in which the carcinogen is the mouse mammary tumor virus (MMTV) which induces clonal premalignant ...
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The receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis.
... the mammary gland, suggested that PTPRB may be a negative regulator of mammary ...primary mouse mammary epithelial cells were transduced in short-term culture (48 h) with either ...
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The receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2 dependent branching morphogenesis
... the mammary gland, suggested that PTPRB may be a negative regulator of mammary ...primary mouse mammary epithelial cells were transduced in short-term culture (48 h) with either ...
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Label retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands
... in mammary glands and how these may relate to putative stem cell ...specific epithelial cell subpopulation whose function is to divide asymmetrically to produce committed transiently amplifying daughters to ...
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PER2 regulation of mammary gland development
... MCF10A cells with and without a short hairpin construct to suppress PER1 and PER2 expression in 3D culture, as we previously described (Schmitt et ...breast epithelial cell line that is under circadian ...
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Mouse Mammary Tumor Virus Suppresses Apoptosis of Mammary Epithelial Cells through ITAM-Mediated Signaling
... MMTV-infected mammary glands is accompanied by altered gene ...RT-qPCR. Mammary glands from control, MMTV HP, and HP YY animals during involution days 2 and 5 are ...
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Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland
... double-labeled cells (EdU + BrdU + ) (Figure ...EdU-positive cells incorporated BrdU during tissue homeostasis, presumably as a re- sult of cyclical estrous cycle changes (Figure ...respectively. ...
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CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non epithelial cells
... the mouse mammary gland rely on two separate rat monoclonal antibodies, 33A10 and JB6, respectively ...these epithelial populations whilst simultaneously avoiding non-epithelial ...luminal ...
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Se methylselenocysteine inhibits phosphatidylinositol 3 kinase activity of mouse mammary epithelial tumor cells in vitro
... TM6 cells treated with MSC are delayed in S phase at about 24 hours ...control cells occur at about 24 ...treated cells beginning at 24 hours might require the cells to be delayed in S phase; ...
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Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF) β and Neu pathway signaling studies: identification of a novel model for TGF β induced epithelial to mesenchymal transition
... When epithelial cancer cells metastasize, they must leave the primary tumor, invade the surrounding tissue, enter the bloodstream, and disseminate to secondary ...of epithelial cell polar- ity, ...
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The WNT controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage
... basal epithelial characteristics by regulating transcription of genes involved in cell proliferation, adhesion and the basal cytoskeleton, including K5 (Carroll et ...luminal cells through repression of ...
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Neuregulin-3 regulates epithelial progenitor cell positioning and specifies mammary phenotype
... The mammary primordium (MP) consists of the primitive mammary epithelium and the adjacent mesenchyme ...the mammary gland during embryogenesis through a series of reciprocal interactions in which ...
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A co culture genome wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation
... 3T3 cells was left to adhere for 24 hours prior to addition of a low density of 184-hTERT-L9 ...epithelial cells. First, the transfection conditions used for the epithelial cells were ...
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Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells.
... To determine the biological consequences of activated int-3 expression on mammary epithelial cells, we transfected the HC11 mouse mammary epithelial cell line 4 with a genomic DNA fragme[r] ...
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A contrasting function for miR-137 in embryonic mammogenesis and adult breast carcinogenesis
... in mouse embryos is used as a model for breast cancer and can be divided into a series of stages ...E10.5 mouse embryos), bilateral mammary lines are formed and epidermal cells of the ...
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Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial mesenchymal transition
... Six1-overexpressing mammary glands exhibit stem/progenitor cell ...of mammary epithelial cells harvested from sucrose-treated, nul- liparous TOSix animals (4922 and 6239 lines) and MTB animals ...
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