mRNA secondary structure
Using mRNA secondary structure predictions improves recognition of known yeast functional uORFs
... predicted mRNA secondary structure can increase the performance of the resulting ...without mRNA secondary structure predictions as part of the background knowledge, were ...when ...
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The Relationship Between Third-Codon Position Nucleotide Content, Codon Bias, mRNA Secondary Structure and Gene Expression in the Drosophilid Alcohol Dehydrogenase Genes Adh and Adhr
... bias, mRNA secondary structure, third-codon position nucleotide distribution, and gene expression, we predicted secondary structures in two related drosophilid genes, Adh and Adhr, which ...
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Effects of mRNA secondary structure on the expression of HEV ORF2 proteins in Escherichia coli
... stable mRNA secondary structure near the start codon, as reported here, seems to play a non-negligible effect in the expression of ...the mRNA second- ary structure of two HBV proteins ...
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Human immunodeficiency virus type 1 gag-pol frameshifting is dependent on downstream mRNA secondary structure: demonstration by expression in vivo.
... In previous studies from this laboratory, chimeric mRNAs containing the HIV-1 shift site were used for in vitro translation in rabbit reticulocyte lysates RRL; mutations of potentially b[r] ...
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Mechanism of ribosome translation through mRNA secondary structures
... the mRNA secondary structure or translation through the single-stranded mRNA, the ribosomal complex samples the hybrid state (State H) only once before undergoing mRNA translocation at ...
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<p>In silico Analysis, Molecular Docking, Molecular Dynamic, Cloning, Expression and Purification of Chimeric Protein in Colorectal Cancer Treatment</p>
... The mRNA structure was adjusted based on low Δ G and energy of the start ...ary structure, a genetic algorithm-based RNA second- ary structure prediction was merged with comparative sequence ...
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High-efficiency expression and secretion of human FGF21 in Bacillus subtilis by intercalation of a mini-cistron cassette and combinatorial optimization of cell regulatory components
... Results: A codon optimized rhFGF21 gene was expressed under the control of a strong inducible promoter P malA in B. subtilis. A mini-cistron cassette (from gsiB) was located upstream of rhFGF21 in expression vector ...
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... of secondary CRYAA mRNA structure was performed using CLC RNA ...CRYAA mRNA secondary structure, while the wild type CRYAA mRNA has a weak or loose secondary ...
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KvLQT1 and KCNE1 K+ Channel Gene Polymorphisms in Long QT Syndrome
... polymorphism, mRNA secondary structure prediction indicated that the variation lead to a change in the secondary structure of mRNA with an increase in free energy of the variant ...
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Bovine-specific nucleotide polymorphisms and mRNA expression of the growth hormone secretagogue receptor 1a (GHSR1a) gene and its genetic association with growth and carcass traits
... GHSR1a mRNA is the only spliced mRNA as there are no other alternative splicing ...RNA secondary structure around the 5’UTR region of the 1b mRNAs between the [ 19-TG ] and [ non-19 - TG ], ...
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Effect of minor SNPs on enzymatic activity regulated by common human haplotypes of the catechol-O-methyltransferase gene
... Common haplotypes of the human COMT gene that are associated with pain sensitivity differ with respect to mRNA secondary structure at a local stem-loop structure in close [r] ...
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B Cell Activating Factor Characterization and Use as a Biomarker in Dogs with Primary Immune-Mediated Thrombocytopenia.
... azathioprine or cyclosporine, to attenuate the adverse immune response driving the platelet destruction (O'Marra et al., 2011). However, several retrospective studies of ITP in dogs and individual case reports list ...
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Importance of the Positive-Strand RNA Secondary Structure of a Murine Coronavirus Defective Interfering RNA Internal Replication Signal in Positive-Strand RNA Synthesis
... RNA secondary structure of the 58-nt region in positive-strand DI RNA synthesis is that the 58-nt region may interact with an- other region of DI RNA to facilitate the stabilization of an RNA ...
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Short and long range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin like 1b
... A distinctive feature of the organizer is its ability to influence distant cell fates as well as to generate axial tissues. Surprisingly, investigation of the interrelationship between these short- and long- range ...
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Ginzinger, Simon Wolfgang (2008): Bioinformatics Methods for NMR Chemical Shift Data. Dissertation, LMU München: Fakultät für Mathematik, Informatik und Statistik
... calculates secondary structure from the three dimensional structure of a ...certain secondary structure type, the hydrogen bond energies and probabilities are combined and compared to a ...
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Engineering of RNA sensors and actuators in living cells
... crystal structure, the targeting region is single stranded, with the "seed" region maintained in A-form conformation by the Cas9 protein, ready for pairing with its target DNA (Jinek et ...crystal ...
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Quantifying secondary structure changes in Calmodulin using 2D-IR spectroscopy
... published structure (PBD 1CFD) giving an RMS-distance value of 4Å. This structure was dominant during the simulations but others included a structure in which the central α-helix was completely ...
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MASSP3: A System for Predicting Protein Secondary Structure
... and structure, the prediction of protein 3D structure has dur- ing recent years become one of the most important tasks in ...ondary structure. In fact, the knowledge of secondary struc- ture ...
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Analysis of Protein Structure based Drug Design Using Comparative Molecular Field Analysis
... the structure- activities relationship of known active ...Quantitative Structure- Activities Relationship (QSAR) approaches like HQSAR, CoMFA and related 3D QSAR approaches became popular amongst medicinal ...
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THE SECONDARY STRUCTURE OF THE FRICTION SURFACE OF THE CONTACT WIRE
... of secondary structures formation on the friction surface of contact wire in the process of operation has been ...modifying secondary material structures within the system «contact wire – current collection ...
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