multinucleated cell
Original Article Expression of PD-L1 in mononuclear cells, multinucleated cells, and foam cells in tenosynovial giant cell tumors
... giant cell tumor (TGCT) is a rare, proliferative and inflammatory disease with activation of colony stimulating factor 1 (CSF1) expression, and exhibits abnormal proliferation of mononuclear cells, multi- ...
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Induction of Cell-Cell Fusion from Without by Human Herpesvirus 6B
... cause cell-cell fusion from without (FFWO), a process that occurs early and is not dependent on de novo synthesis of viral glycoproteins ...induce multinucleated cells in MT-4 cultures, the ability ...
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Feline immunodeficiency virus decreases cell-cell communication and mitochondrial membrane potential.
... The astroglia were primary cell cultures that supported an acute infection, producing large multinucleated cells, and the CRFK were immortalized cultured cells supporting persistent FIV [r] ...
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Limited Functional Redundancy and Oscillation of Cyclins in Multinucleated Ashbya gossypii Fungal Cells
... in multinucleated cells with asynchronous ...oscillating cell cycle proteins, but it is unclear how fluctuating protein gradients can be established in multinucleated cells where nuclei in different ...
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Oral spindle cell lipomas
... Microscopically, both lesions presented a solid prolif- eration of mature fat cells intermixed with bundles of connective tissue (Figure 2(a)). Fat cells showed a large univacuolated cytoplasm with a small, flattened ...
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The role of cadherin in the generation of multinucleated osteoclasts from mononuclear precursors in murine marrow
... osteoclast)-positive multinucleated cell (TRAP-positive MNC) by inhibiting the fusion of mononuclear osteoclast precursors, but not proliferation of these cells or their attachment to plastic dish ...the ...
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Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype
... OCLs from individuals with Paget’s disease contain nuclear and cytoplasmic inclusions that have been reported to cross-react with antibodies to nucleocap- sids from paramyxoviruses, including MV, respiratory syncytial ...
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Characterization of Human Cytomegalovirus Glycoprotein-Induced Cell-Cell Fusion
... for cell physiology, including protein phosphorylation and calcium ion flux (28, ...and cell-cell ...the cell lines we tested, including immortalized fibroblasts, but not secondary fibroblast ...
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Multinucleation followed by an acytokinetic cell division in myxofibrosarcoma with giant cell proliferation
... bizarre multinucleated giant cells with abundant eosinophilic cytoplasm ...these multinucleated cells are considered to be neoplastic and possess atypical nuclei or mitotic changes ...mechanism ...
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Multinucleated stromal giant cells in the gastroesophageal junctional and gastric mucosa: a retrospective study
... of multinucleated cells and mimickers are sometimes found in the upper gastrointestinal ...tract. Multinucleated histiocytes are seen in granu- lomas of various etiologies and foreign-body giant cell ...
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Connexin mimetic peptide Gap 27 decreases osteoclastic activity
... the cell number seems to be specific to oste- oclasts, since only the number of TRAP-positive cells is affected by the ...and multinucleated osteoclasts is decreased when gap-junctional communi- cation is ...
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Analysis of mitosis and anti-mitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics
... became multinucleated (Fig. 3f–j). Multinucleated cells did not re-enter mitosis but did sometimes die ...of cell death, during mitosis or from a multinucleated state, resembled apoptosis with ...
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An observational study of giant cell interstitial pneumonia and lung fibrosis in hard metal lung disease
... Figure 3 Representative images of light microscopic findings of a lung specimen from case 10 with hard metal lung disease pathologically diagnosed as usual interstitial pneumonia pattern. (A,B) A low magnification view ...
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T Cell-Macrophage Fusion Triggers Multinucleated Giant Cell Formation for HIV-1 Spreading
... of cell-to-cell contacts, leading to virus transfer and the accumulation of mature virus particles in cytoplasmic membrane compartments in macrophages after only 6 h of coculture with infected T cells, ...
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Therapeutic potentials of naringin on polymethylmethacrylate induced osteoclastogenesis and osteolysis, in vitro and in vivo assessments
... Abstract: Wear debris associated periprosthetic osteolysis represents a major pathological process associated with the aseptic loosening of joint prostheses. Naringin is a major flavonoid identified in grapefruit. ...
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A diagnostic dilemma in breast pathology – benign fibroadenoma with multinucleated stromal giant cells
... spindle cell tumours, then suggests that the Vimentin/CD34 positive fibroblast of mammary stroma could be the result of differentiation from a pluripotential mesenchymal precursor cell with the potential to ...
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The pathogenicity of Staphylococcus epidermidis on the intestinal organs of rats and mice: an experimental investigation
... and multinucleated hepatocytes in the liver, infiltration of the kidney tubule interstitial by chronic inflammatory cells, coagulative necrosis of the kidney, spleen, intestine and stomach cells as well as marked ...
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Aberrant ADAM10 expression correlates with osteosarcoma progression
... that multinucleated giant cells are not osteo- clasts, but angiogenic tumor cells in which ADAM10/ Notch1 signaling is activated and might be implicated in tumor cell ...
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Human giant cell tumors of bone identification and characterization of cell types
... giant cell tumors of bone were characterized on the basis of morphological features, proliferative capacity, presence of granulocyte-monocyte antigens, receptors for skeletal hormones, and soluble cell ...
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Case Report Primary pleomorphic liposarcoma of liver: a case report and review of the literature
... Most patients with pleomorphic liposarcoma have no obvious symptoms at presentation especially deeply locate [19]. There are not dis- tinctive changes in clinical examination and routine laboratory screening, which makes ...
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