Mushroom tyrosinase
Prevention of Experimental Autoimmune Vitiligo by Oral Administration of Mushroom Tyrosinase
... of mushroom tyrosinase suppresses clinical and histological symptoms of the disease and profoundly suppresses T cell proliferative response to mushroom tyrosinase, and it increases ...
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Inhibitory kinetics of enterolactone on mushroom tyrosinase
... In this study, we investigated the inhibitory effect of enterolactone on mushroom tyrosinase. The results showed that enterolactone significantly inhibited its monophenolase and diphenolase activities. The ...
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In-Silico ANALYSIS OF THE GENE AND PROTEIN SEQUENCES OF THE ENZYME MUSHROOM TYROSINASE (POLYPHENOL OXIDASE, PPO)
... of tyrosinase in cancer as some papers suggest a tumor-suppressing effect of mushroom tyrosinase, whereas others predict a possible role in ...by tyrosinase to a quinone and another oxidation ...
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<p>Evaluation of novel pyrimidine derivatives as a new class of mushroom tyrosinase inhibitor</p>
... the tyrosinase inhibition ability of aromatic amines and anilines, we were encouraged to synthesize some new derivatives based on pyrimidine and aniline ...room tyrosinase were then evaluated. ...
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Inhibitory effects of the extracts of Ziziphora clinopodioides Lam on mushroom tyrosinase activity
... Mushroom tyrosinase (Sigma, USA), L-DOPA, kojic acid (Aladdin Industrial Corporation), rosmarinic acid (China Pharmaceutical and Biological Products, China), dimethyl sulfoxide, sodium dihydrogen phosphate, ...
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Umbelliferone-Thiazolidinedione Hybrids as Potent Mushroom Tyrosinase Inhibitors
... of mushroom tyrosinase was reported by Li et ...by mushroom tyrosinase [13, ...excluded. Tyrosinase activity toward L-tyrosine as monophenol substrate requires lag-phase for its ...
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Inhibition of Mushroom Tyrosinase by Aliphatic Alcholols
... The inhibitory mechanisms of alcohols on mushroom tyrosinase, during the oxidation of dopamine hydrochloride, were determined from Linweaver-Burk double reciprocal plots. Fig. 3 shows the double-reciprocal ...
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Molecular docking studies of embelin (simple natural benzoquinone) and its derivatives as a potent tyrosinase inhibitor
... castaneoglobisporus tyrosinase), in our earlier study [17] we reported molecular docking of L-Cysteine with that of Streptomyces castaneoglobisporus ...castaneoglobisporus tyrosinase as targeted protein for ...
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Indole-3-carbaldehyde: a tyrosinase inhibitor from fungus YL185
... Abstract Indole-3-carbaldehyde (1) was isolated as a tyro- sinase inhibitor from the ethyl acetate-soluble fraction of extracellular fluids of unknown fungus YL185. The partial sequencing data of 18S ribosomal DNA (18S ...
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Design, synthesis, and anti-melanogenic effects of (<em>E</em>)-2-benzoyl-3-(substituted phenyl)acrylonitriles
... cellular tyrosinase activity and melanin biosynthesis in murine B16F10 melanoma cells and their ability to inhibit mushroom tyrosinase ...cellular tyrosinase activity in B16F10 cells in a ...
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EuropePMC-PMC4926015.pdf
... factor, tyrosinase, tyrosinase-related protein 1, and tyrosinase-related protein 2 showed that EA extract inhibited protein expression mentioned above whereas DM extract had the opposite ...
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Design, synthesis, and antimelanogenic effects of (2-substituted phenyl-1,3-dithiolan-4-yl)methanol derivatives
... B16F10 cells were used to evaluate the depigmenting activities of the PDTM analogues. PDTM3 was chosen for the cell-based experiments, due to its potent mushroom tyrosinase-inhibitory effect and its lack of ...
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Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies
... In case of compounds 4c and 6d, Lineweaver-Burk plot gave a family of straight lines, all of which intersected at the same point on the x-axis (Figures 1A and 4A). The analysis showed that 1/V max increased to a new ...
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Journal of Applied Pharmaceutical Science
... The present study was carried out to evaluate antioxidant and anti-tyrosinase activities from Piper officinarum stems, as well as investigation of its chemical constituents. In a series of in vitro assays, ...
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Search | Preprints
... Inhibitory effects on mushroom tyrosinase activity of target compounds.. Binding mode prediction of compound 3g with mushroom tyrosinase (PDB ID: 2Y9X).[r] ...
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Thiopurine Drugs Repositioned as Tyrosinase Inhibitors
... Figure 6. Predicted binding modes of thiopurine inhibitors in this study. (A) Overlaid poses against mushroom tyrosinase. Two copper atoms in tyrosinase are indicated as orange spheres. Predicted ...
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Primary processing neuropils associated with the malleoli of camel spiders (Arachnida, Solifugae): a re-evaluation of axonal pathways
... The ventral nerve cord (subesophageal part of the syn- ganglion) shows a conspicuous architecture. Ventrally to the neuromeres associated with the walking legs, paired medial projections from the malleoli extend anteriad ...
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Inhibition of melanogenesis by Gaillardia aristata flower extract
... inhibited tyrosinase, a key enzyme cata- lyzing the rate-limiting step in melanin biosynthesis, tyrosinase zymography and tyrosinase luciferase reporter activation assays of enzyme activity were ...
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The functional property of royal jelly 10 hydroxy 2 decenoic acid as a melanogenesis inhibitor
... The cells were washed 3 times in ice-cold PBS and lysed in RIPA buffer (pH 7.4, 50 mM tris, 0.1% SDS, 50 mM NaCl, 1% NP-40, 1 mM PMSF, 10 μg/mL aprotinin and 10 μg/mL leupeptin). An aliquot of the lysate was used to ...
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Investigation of Temperature and Humidity Control System for Mushroom House
... the mushroom house is the important part of the physical ...the mushroom health and production. The mushroom house will trap the solar radiation and increase the environment ...the mushroom ...
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