mycolic acids
Arylamine N acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target
... normal mycolic acid synthesis, for example through ...Although mycolic acids and their methyl esters are greatly affected, fatty acids are only diminished ...fatty acids before ...
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Trans cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis –induced inflammation and virulence
... of mycolic acids of TDM in ...of mycolic acids on TDM is a critical area of investigation for understanding the immunopathogenesis of ...
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High performance liquid chromatography analysis of mycolic acids as an aid in laboratory identification of Rhodococcus and Nocardia species
... High-performance liquid chromatography analysis of the p-bromophenacyl esters of mycolic acids from whole organisms gave chromatographic patterns that were useful in differentiation of R[r] ...
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High performance liquid chromatography patterns of mycolic acids as criteria for identification of Mycobacterium chelonae, Mycobacterium fortuitum, and Mycobacterium smegmatis
... High-Performance Liquid Chromatography Patterns of Mycolic Acids as Criteria for Identification of Mycobacterium chelonae, Mycobacterium fortuitum, and Mycobacterium smegmatis W.. RAY BU[r] ...
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Sensitive Voltammetric Sensor for Fast Detection of Mycolic Acids Present in Mycobacteria
... The method proposed was applied to the analysis of M. smegmatis in drinking water collected from a Drinking Water Treatment Plant, but the sample does not show any traces of mycobacteria. The results were confirmed by ...
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High performance liquid chromatography patterns of Mycobacterium gordonae mycolic acids
... High-performance liquid chromatography HPLC characterization of mycobacterial mycolic acids has been in use for several years and is gradually finding its way into clinical laboratories [r] ...
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Adaptive response of Rhodococcus opacus PWD4 to salt and phenolic stress on the level of mycolic acids
... the mycolic acids of Rhodococcus erythro- polis E1 was investigated by Sokolovská et ...even-numbered mycolic acids, whereas during growth on odd-numbered carbon chained substrates both even- ...
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Determination of molecular species composition of C80 or longer chain alpha mycolic acids in Mycobacterium spp by gas chromatography mass spectrometry and mass chromatography
... The rapidly growing mycobacteria showed several types of profiles in a-mycolic acid composition, based on the average carbon numbers, the structure of a unit or a-alkyl branch, and the a[r] ...
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Comparison of Methods for Identification ofMycobacterium abscessus and M chelonae Isolates
... Mycobacterium abscessus and Mycobacterium chelonae are two closely related species that are often not distinguished by clinical laboratories despite the fact they cause diseases requiring different treatment regi- mens. ...
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Improved rapid identification of mycobacteria by combining solid phase extraction with high performance liquid chromatography analysis of BACTEC cultures
... low-molecular-weight mycolic acids that were not characteristic of ...detectable mycolic acids and one contained a mycolic acid pattern resembling the pattern char- acteristic of the ...
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Identification of mycolic acid forms using surface-enhanced Raman scattering as a fast detection method for tuberculosis
... of mycolic acids (MAs) that are both synthetic origin and actual extracts from the mycobacteria species were obtained by label-free direct detection ...
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Financial Intermediation and Economic Growth: Bank Credit Maturity and Its Determinants
... envelope, mycolic acids content and the composition of the cell envelope were ...for mycolic acid production (Candida albicans C30) ...the mycolic acid analysis, therefore it was not ...
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Mycobacterium conspicuum sp nov , a new species isolated from patients with disseminated infections
... the mycolic acids extracted from whole cells as reported previously ...fatty acids were saponified with a 25% KOH solution in 50% ethanol for 1 h in an autoclave at 121 8 ...HCl, mycolic ...
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Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria
... M ycobacteria have a complex cell wall, which is crucial for maintaining cell integ- rity, protects against environmental stress, provides a barrier against access of potentially harmful molecules into the cell, and ...
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Mycobacterium heckeshornense sp nov , a New Pathogenic Slowly Growing Mycobacterium sp Causing Cavitary Lung Disease in an Immunocompetent Patient
... separating mycolic acids by TLC in two ...fatty acids and alcohols classified the three isolates to the ...the mycolic acid methyl esters released a saturated fatty acid methyl ester with a ...
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Keto Mycolic Acid Dependent Pellicle Formation Confers Tolerance to Drug Sensitive Mycobacterium tuberculosis
... ABSTRACT The chronic nature of tuberculosis (TB), its requirement of long duration of treatment, its ability to evade immune intervention, and its propensity to relapse after drug treatment is discontinued are ...
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TWEEN 80 ALTERS THE PRODUCTION RATIO OF PHARMACEUTICALLY IMPORTANT STEROID INTERMEDIATES, 4 AD AND ADD DURING BIOTRANSFORMATION OF SOY STEROL BY MYCOBACTERIUM SP NRRL B 3805
... Mycobacterium cell wall is a complex meshwork of peptidoglycan and arabinogalactan on which huge molecules of mycolic acids are attached. This structural complexity and hydrophobicity is thought to be a ...
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Gas chromatographic analysis of mycolic acid cleavage products in mycobacteria
... When the samples were analyzed at high injector temperatures of 300 to 350°C, characteristic thermal cleavage products from mycolic acids, C220, C240, or C260 fatty acid methyl esters, w[r] ...
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Rapid, Standardized Method for Determination of Mycobacterium tuberculosis Drug Susceptibility by Use of Mycolic Acid Analysis
... measuring mycolic acid levels by high-performance liquid chromatogra- phy (HPLC) (10, ...21). Mycolic acids are high-molecular-weight ␣ -alkyl,  -hydroxy fatty acids containing an ␣ branch of ...
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Identification of mycobacteria by high performance liquid chromatography
... Previously, we reported high-performance liquid chromatography HPLC patterns of the mycolic acids of seven species of mycobacteria that make up 90% of mycobacterial isolates in clinical [r] ...
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