N-methyl-d-aspartate (NMDA)
Changes in Striatal N-methyl-D-aspartate (NMDA) Stimulation of Dopamine Release and Receptor Subunit Expression During Expression of and Recovery from MPTP-Induced Parkinsonism
... as N-methyl-D- aspartate (NMDA), into the striatum of rats and cats stimulates dopamine release (for review see 15 ...rats, NMDA-stimulated dopamine release has been shown to ...
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Anti-leucine rich glioma inactivated 1 protein and anti-N-methyl-D-aspartate receptor encephalitis show distinct patterns of brain glucose metabolism in 18F-fluoro-2-deoxy-d-glucose positron emission tomography
... the N- methyl-D-aspartate (NMDA) receptor ...and NMDA receptor mediated currents in hippocampal cultures [10,11] as well as to increased corti- comotor hyperexcitability in rats ...
11
N-methyl-D-aspartate (NMDA) receptor expression and function is required for early chondrogenesis
... The amino acid glutamate is the major excitatory neurotransmitter in the mammalian central nervous sys- tem (CNS). It can act on ionotropic (iGluR) and metabo- tropic (mGluR) receptors. iGluRs are ligand-gated non- ...
19
The importance of N methyl d aspartate (NMDA) receptors in subtraction of electrosensory reafference in the dorsal nucleus of skates
... blocking NMDA receptors did not change the AEN baseline firing ...that NMDA receptors coexist postsynaptically with other types of glutamate receptors (for a review, see Mayer and Westbrook, 1987), and both ...
10
N methyl D aspartate (NMDA) mediates vascular relaxation via nitric oxide (NO) in rats but not in mice
... Figure 2. Mean of the size of the amperometric transient peaks monitored in CD rat, CD1 and C57BL6 mice aortic rings to which Krebs (vehicle, 5µl), Substance P (25 µM) or NMDA (2.5 µM) were added (n = 6 ...
5
N methyl D aspartate (NMDA) and non NMDA type glutamate receptors are present on squid giant axon Schwann cells
... Here we present evidence, for the first time in any glial preparation, that NMDA type glutamate receptors are present in the adaxonal glial or Schwann cells of the giant axon of the trop[r] ...
8
Metabotropic glutamate receptor mediated modulation of N-methyl-D-aspartate (NMDA) receptor-channels in the rat hippocampus
... of NMDA mediated responses due to its abundance in the CNS (Brandt, et aL, 1987) and also its ability to readily phosphorylate other ion channels (Ross et ...potentiate NMDA mediated ...the NMDA ...
168
N Methyl d Aspartate (NMDA) Receptor Blockade Prevents Neuronal Death Induced by Zika Virus Infection
... have exploited the hypothesis that ZIKV-induced neurodegeneration can be rescued by blocking NMDA overstimulation with memantine. Our results show that ZIKV ac- tively replicates in primary neurons and that virus ...
16
Novel glutamatergic drugs for the treatment of mood disorders
... NMDAR, N-methyl-D-aspartate receptor; CS, chronic stress; TST, tail suspension test; FST, forced swim test; LH, learned helplessness; NSFT, novelty- suppressed feeding test; GLYX-13, ...
12
Inhibition of vesicular stomatitis virus infection by nitric oxide.
... compound N-acetylpenicillamine (NAP) had no ...with N-methyl- D -aspartate (NMDA) led to significant inhibition of viral production by cells infected at the three doses of virus ...
6
AMELIORATIVE EFFECT OF PAPAIN ON BEHAVIORAL AND BIOCHEMICAL ALTERATIONS IN IN SILICO AND IN VIVO MODELS OF NEUROPATHIC PAIN IN RATS
... on N-methyl D-aspartate (NMDA) receptor down-regulation pathway by using in-silico studies and on oxidative stress in-vivo model of neuropathic pain in rats via partial sciatic nerve ...
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Xenon triggers pro inflammatory effects and suppresses the anti inflammatory response compared to sevoflurane in patients undergoing cardiac surgery
... Xenon’s well-known neuro- and cardioprotective proper- ties render this noble gas an attractive alternative to con- ventional volatile anaesthetics, which has been intensively investigated in a variety of experimental ...
10
Low Dose Ketamin
... NMDA (N-methyl-D-aspartate) receptor antag- onist administered as an additional medication pain management. Receptor N-methyl-D Aspartate receptors are ...
7
Pharmacokinetics and Its Application to Dosage Design in Veterinary Medicine.
... The role of N-methyl-D-aspartate (NMDA) receptors in pain: a review. Porter & Meldrum, 2004 Antiseizure Drugs in: Basic and Clinical Pharmacology. Katzung BG ed. New York, NY; McGra[r] ...
162
Cardiovascular medication burden in dementia disorders: a nationwide study of 19,743 dementia patients in the Swedish Dementia Registry
... In SveDem, the following classes of drugs were registered at the beginning of the diagnostic workup with the possible answers ‘yes’/‘no’/‘do not know’: CV drugs, cholinesterase inhibitors (ChEI), ...
9
Efficacy of Low-dose Dextromethorphan in the Treatment of Nonketotic Hyperglycinemia
... NKH, nonketotic hyperglycinemia; CSF, cere- brospinal fluid; NMDA, N-methyl-D-aspartate; EEG, electroen- cephalography; DM, dextromethorphan.. Nonketotic hyperglycinemia (NKH) is a rare [r] ...
5
NMDA Receptor Antagonists for the Treatment of Neuropathic Pain Compared to Placebo: A Systematic Review and Meta analysis
... of N-Methyl-D-aspartate (NMDA) receptor antagonists on neuropathic pain disorders that can occur in the orofacial ...a NMDA receptor antagonist to treat spontaneously occurring ...
13
Soluble epoxide hydrolase inhibitor enhances synaptic neurotransmission and plasticity in mouse prefrontal cortex
... and N- methyl-D-aspartate receptor (NMDA) receptors [22, ...23]. NMDA receptor activation induces Ca 2+ influx and triggers Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) ...
13
Immunohistochemical evaluation of akabane virus infection in aborted and new born calves
... ABSTRACT: The present study was aimed at the detection and describing the lesions of akabane virus in foetal and new-born calves tissues using immunohistochemical and immunofluorescence techniques. Akabane virus lesions ...
9
Neuroprotective strategies against calpain-mediated neurodegeneration
... Abstract: Calpains are calcium-dependent proteolytic enzymes that have deleterious effects on neurons upon their pathological over-activation. According to the results of numerous studies to date, there is no doubt that ...
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