Na+:K+:2Cl− cotransporter
Na K 2Cl cotransporter gene expression and function during enterocyte differentiation Modulation of Cl secretory capacity by butyrate
... basolateral Na-K-2Cl cotransporter (NKCC1) is a key component of the intestinal crypt cell secretory ...bumetanide-sensitive K+ (86Rb) uptake in both HT29 cells and the Cl--secreting ...
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Expression of the mouse Na K 2Cl cotransporter, mBSC2, in the terminal inner medullary collecting duct, the glomerular and extraglomerular mesangium, and the glomerular afferent arteriole
... the Na-K-2Cl cotrans- porter are both highly expressed in the mammalian kidney (4, 5, 7, ...the Na-K-2Cl cotransporter in the mouse ...respective cotransporter ...
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α 1 Na,K-ATPase and Na,K,2Cl-Cotransporter/D3mit3 Loci Interact to Increase Susceptibility to Salt-Sensitive Hypertension in Dahl SHSD Rats
... 1 Na,K-ATPase ( 1NK) as a hyperten- sion susceptibility gene in Dahl salt-sensitive (Dahl S) rats, we determined whether 1NK interacts with an- other renal epithelial Na transporter to increase ...
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Expression of the Na K 2Cl cotransporter by macula densa and thick ascending limb cells of rat and rabbit nephron
... Molecular cloning and preparation of riboprobes. Riboprobe was prepared from a 383 bp partial cDNA fragment of the mouse bumet- anide-sensitive Na-K-2Cl cotransporter, NKCC2 (7). This cDNA ...
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The Na+/K+/2Cl cotransporter in the sea bass Dicentrarchus labrax during ontogeny: involvement in osmoregulation
... The Na + /K + /2Cl – cotransporter (NKCC) is one of these transmembrane proteins whose pattern of expression at different osmoregulatory sites is ultimately responsible for the adaptation of ...
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Beta adrenergic upregulation of the Na(+) K(+) 2Cl cotransporter in rat parotid acinar cells
... acinar Na(+)-K(+)-2Cl- cotransporter would lead to an increase in acinar chloride uptake across the basolateral membrane, and consequently, an increase in overall chloride and fluid ...
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Effect of osmotic shrinkage and hormones on the expression of Na+/H+ exchanger 1, Na+/K+/2Cl– cotransporter and Na+/K+ ATPase in gill pavement cells of freshwater adapted Japanese eel, Anguilla japonica
... Gill epithelial culture has been established in freshwater trout for the study of unidirectional ion fluxes and for the characterization of ion transporter properties (Kelly et al., 2000; Kelly and Wood, 2001c; Kelly and ...
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Functional classification of mitochondrion rich cells in euryhaline Mozambique tilapia (Oreochromis mossambicus) embryos, by means of triple immunofluorescence staining for Na+/K+ ATPase, Na+/K+/2Cl cotransporter and CFTR anion channel
... proteins: Na + /K + -ATPase, Na + /K + /2Cl – cotransporter and Cl – channel (Silva et ...A Na + /K + - ATPase, which is localized to the basolateral membrane of ...
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Variation in salinity tolerance, gill Na+/K+ ATPase, Na+/K+/2Cl– cotransporter and mitochondria rich cell distribution in three salmonids Salvelinus namaycush, Salvelinus fontinalis and Salmo salar
... that Na + /K + -ATPase was already upregulated in freshwater as a preparative adaptation for seawater entry, and accounts for the excellent euryhalinity of salmon smolts compared to lake trout and brook ...
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Identification of a sea urchin Na(+)/K(+)/2Cl(−) cotransporter (NKCC): microfilament dependent surface expression is mediated by hypotonic shock and cyclic AMP
... Given the unique physicochemical and morphological changes in coelomocytes in response to alterations in extracellular tonicity, we set out to identify some of the steps involved in the cascade of events leading to cell ...
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Differential expression of gill Na+,K+ ATPaseα and β subunits, Na+,K+,2Cl cotransporter and CFTR anion channel in juvenile anadromous and landlocked Atlantic salmon Salmo salar
... On the other hand, the lack of a preparatory increase of 1 mRNA levels in landlocked salmon, despite elevated enzyme activity in May and June, and further, decreasing levels of 1 mRNA [r] ...
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Failure of spermatogenesis in mouse lines deficient in the Na+ K+ 2Cl– cotransporter
... The salt and water reabsorptive function of the apical NKCC2 isoform of the cotransporter in the thick ascending limb of Henle cells is well established, based on the large natriuretic effect of loop diuretics ...
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Influence of salinity on the localization of Na+/K+ ATPase, Na+/K+/2Cl cotransporter (NKCC) and CFTR anion channel in chloride cells of the Hawaiian goby (Stenogobius hawaiiensis)
... lamellae was 4.4-fold, and combining the two yields an overall estimated 10-fold increase in CFTR for the entire gill. This is likely to be a minimal estimate for change, as the staining intensity is only ...
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Ischemic preconditioning stimulates sodium and proton transport in isolated rat hearts
... One or more brief periods of ischemia, termed preconditioning, dramatically limits infarct size and reduces intracellular acidosis during subsequent ischemia, potentially via enhanced sarcolemmal proton efflux ...
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Mild spherocytosis and altered red cell ion transport in protein 4 2–null mice
... Increased Na- K pump activity and passive cation permeabilities, decreased K-Cl cotransporter activity, and normal Na-K- 2Cl cotransporter and Na/H exchanger ...
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Basolateral ion transport mechanisms during fluid secretion by Drosophila Malpighian tubules: Na+ recycling, Na+:K+:2Cl– cotransport and Cl– conductance
... cotransporter can be ruled out on the basis of the electrochemical potentials reported above, and also on the basis of the effects of bumetanide in the presence of ouabain. It is worth noting that recent analysis ...
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Microfilament dependent activation of Na+/K+/2Cl cotransport by cAMP in intestinal epithelial monolayers
... a Na+ absorptive current in response to apical addition of a Na+ ionophore, was not different between control and phalloidin-loaded ...stimulate Na+/K+/2Cl- cotransport ...
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Intracellular ion activities in Malpighian tubule cells of Rhodnius prolixus: evaluation of Na+ K+ 2Cl cotransport across the basolateral membrane
... cotransporter may be into or out of the cell depending on the sum of the chemical potential gradients of the transported ions, and the transporter can be inhibited by loop diuretics such as furosemide or ...
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The renal electrogenic Na+:HCO 3 cotransporter
... directly measured. However, it has been deduced by Soleimani et al. (1987) on the basis of thermodynamic data obtained from membrane vesicles prepared from the basolateral membranes of rabbit proximal tubules. The ...
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Localization and rapid regulation of Na+/myo inositol cotransporter in rat kidney
... In situ hybridization revealed that SMIT is predominantly present in the medullary and cortical thick ascending limbs of Henle's loop TALH and macula densa cells.. Less intense signals w[r] ...
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