Nanoparticles for oral delivery
Evaluating the potential of polymer nanoparticles for oral delivery of paclitaxel in drug-resistant cancer
... the oral route. Furthermore, the nanoparticles can partially circumvent multidrug resistance in ...preparing nanoparticles for drug ...enable oral delivery of otherwise poorly ...
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Simvastatin solid lipid nanoparticles for oral delivery: Formulation development and In vivo evaluation
... Lipid Nanoparticles of Simvastatin for Improved Oral Delivery Solid lipid nanoparticles have been increasingly utilised for improving oral bioavailability of ...poor oral ...
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Evaluating the potential of cubosomal nanoparticles for oral delivery of amphotericin B in treating fungal infection
... lipid nanoparticles, 5 phytantriol (PHY) cubosomes, 6,7 self-emulsifying drug delivery systems (SEDDS), 8,9 and ...two oral lipid-based formulations draw attention to their ability to enhance ...
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“Nanoparticles: Therapeutic Benefits for Diabetes Mellitus by Oral Delivery” by Raksha Acharya, Prabha Singh, India.
... The nanoparticles were developed using Ionotropic gelation method by incorporating polymers such as chitosan and xanthan gum, sodium tripolyphosphate as a cross-linking agent, in which the hydrophilic polypeptide ...
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Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake
... lipid nanoparticles (SLNs) are submicron (50–1,000 nm) colloidal particulate systems composed of physiologically tolerable lipid components, which remain in the solid state at room ...drug delivery system ...
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Poly(n-butylcyanoacrylate) nanoparticles for oral delivery of quercetin: preparation, characterization, and pharmacokinetics and biodistribution studies in Wistar rats
... Dovepress PBca nanoparticles for oral delivery of quercetin by 35.59% due to NPs’ coating with P-80. Likewise, free QT was evaluated after 6 hours of incubation in SIF. The percentages of the drug ...
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Novel PLGA-based nanoparticles for the oral delivery of insulin
... Dovepress Novel Plga-based nanoparticles permeation chromatography. The PLGA copolymers have been extensively employed as a carrier for oral delivery of insulin. 29 In this study, the NPs have been ...
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Application of polymeric nanoparticles in oral delivery of recombinant human erythropoietin: A review
... ERYTHROPOIETIN ORAL DELIVERY Nanoparticles: Nanotechnology is a rapidly expanding field, encompassing the development of man-made materials in the 5-200 nanometer size ...targeted delivery. ...
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Antitumor efficacy of Folic Acid conjugated Polymeric Nanoparticles of SN-38 after oral delivery
... based nanoparticles 41 ...These nanoparticles are better than other synthetic nanoparticles as they are more stable, have simple preparation methods, low toxicity and can be given by versatile routes ...
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Development of Solid Lipid-polymer Hybrid Nanoparticles as Potential Oral Delivery Systems for Lipophilic Bioactive Compounds
... Thus, in the second and third study, we tried to develop a synthetic surfactant-free and cross-linker-free method was developed to fabricate SLPN with natural biomaterials. In this study, BSA and dextran were first ...
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ASENAPINE MALEATE LOADED SOLID LIPID NANOPARTICLES FOR ORAL DELIVERY
... the nanoparticles, vital for providing sustained drug levels in the ...Smaller nanoparticles lead to a shorter average diffusion path of the ASM entrapped and lead to faster rate of release of the entrapped ...
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Evaluating the potential of cubosomal nanoparticles for oral delivery of amphotericin B in treating fungal infection
... The oral administration of amphotericin B (AmB) has a major drawback of poor ...the oral efficacy of ...after oral administration, to investigate its therapeutic ...enhance oral efficacy, ...
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DEVELOPMENT AND OPTIMIZATION OF ZALEPLON LOADED EUDRAGIT® NANOPARTICLES FOR ORAL DELIVERY: IN-VITRO AND IN-VIVO EVALUATION
... CONCLUSION The Za-NPS were prepared by single emulsification/ solvent evaporation technique using different formulation variables of (polymer amount, organic phase volume and PVA concentrations). The optimization of ...
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Application of nanoparticles for oral delivery of acid-labile lansoprazole in the treatment of gastric ulcer: in vitro and in vivo evaluations
... fluorescence nanoparticles Coumarin-6 is widely used as a fluorescence marker for con- focal microscopic investigation due to its high fluorescence ...fluorescence nanoparticles for ...rescence ...
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<p>Cholate-modified polymer-lipid hybrid nanoparticles for oral delivery of quercetin to potentiate the antileukemic effect</p>
... All other chemicals were of analytical grade and used as received. Preparation of QUE-cPLNs QUE-cPLNs were prepared by the nanoprecipitation techni- que followed by evaporation to remove the organic solvent according to ...
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Oral delivery of insulin loaded nanoparticles in diabetic rabbits and in sheep
... these nanoparticles as a drug carrier for oral administration in alloxan-induced diabetic rabbits and in ...After oral administration of ILNP to diabetic rabbits, a signifi - cant hypoglycemic eff ect ...
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Oral Delivery of ascorbic acid stabilized rifampicin nanoparticles for enhanced bioavailability of rifampicin.
... of nanoparticles in the ...drug delivery applications 21 ...drug delivery systems used for chronic ...producing nanoparticles containing antituberculous drugs using natural polymer such as ...
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FORMULATION, OPTIMIZATION AND EVALUATION OF ENROFLOXACIN SOLID LIPID NANOPARTICLES FOR SUSTAINED ORAL DELIVERY
... Conclusion: The results indicated that SLNs might be a promising delivery system to prolong and enhance the pharmacological activity of enrofloxacin. Keywords: Enrofloxacin, Solid lipid nanoparticle, Hot ...
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NOVEL NANOPARTICLES FOR THE ORAL DELIVERY OF LOW MOLECULAR WEIGHT HEPARIN: IN VITRO AND IN VIVO ASSESSMENT
... enhanced oral bioavailability was attributed to the interaction of AG and CH, which prevented the degradation of drug in gastric ...PEC nanoparticles then enter the small intestine where the AG gets slowly ...
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Oral Delivery of DMAB Modified Docetaxel Loaded PLGA TPGS Nanoparticles for Cancer Chemotherapy
... for oral administration of anticancer drugs, which include DMAB-modified PLGA nanoparticles, unmodified PLGA-TPGS nanoparticles and DMAB-modified PLGA-TPGS ...improving oral drug ...
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