NDM-5
<p>Characterization of a novel <em>bla</em><sub>NDM-5</sub>-harboring IncFII plasmid and an <em>mcr-1</em>-bearing IncI2 plasmid in a single <em>Escherichia coli</em> ST167 clinical isolate</p>
... co-produce NDM-5 and MCR-1. S1-PFGE and Southern blotting showed that bla NDM-5 and mcr-1 genes were located on ~95 kb and ~65 kb plasmids, ...bla NDM-5 - and mcr-1-bearing ...
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<p>First Reported Nosocomial Outbreak Of NDM-5-Producing <em>Klebsiella pneumoniae</em> In A Neonatal Unit In China</p>
... between the caregivers and the newborns hospitalized in the same ward is the most likely route of the transmission of the isolates. Hospital infection department took strict measures to control the outbreak in the ...
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<p>Plasmid-Encoded <em>bla<sub>NDM-5</sub></em> Gene That Confers High-Level Carbapenem Resistance in <em>Salmonella</em> Typhimurium of Pork Origin</p>
... According to the MLST results, the SH160 strain belongs to ST34, which is one of the most prevalent types of S. Typhimurium. Moreover, ST34 clones have raised international concern regarding their rapid preva- lence and ...
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<p>Emergence of Almost Identical F36:A-:B32 Plasmids Carrying <em>bla</em><sub>NDM-5</sub> and <em>qepA</em> in <em>Escherichia coli </em>from Both Pakistan and Canada</p>
... aad2-hp-dfrA12- Δ intI1, which was identical with the E. coli plasmid pM309-NDM5 (F36:A4:B- or F36:A20:B-, AP01 8833.1), pNDM-d2e9 (F2:A-:B-, CP026201.1), and pAMA1 167-NDM-5 (F1:A1:B49, CP024805.1) from ...
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Emergence of tigecycline resistance in <em>Escherichia coli</em> co-producing MCR-1 and NDM-5 during tigecycline salvage treatment
... bla NDM-5 in an ~ 33–55 kb plasmid (Figure S1), belonging to IncHI2 and IncX3 by analysis of whole genome ...bla NDM-5 was relatively similar to the sequences of the bla NDM-5 ...
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<p>Characterization of the IncFII-IncFIB(pB171) Plasmid Carrying <em>bla</em><sub>NDM-5</sub> in <em>Escherichia coli</em> ST405 Clinical Isolate in Japan</p>
... by NDM-5-producing isolates were not ...producing NDM enzymes are rarely reported among hospitalized patients in Japan, attention should be paid to the community prevalence of such strains to moni- ...
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Co-production of MCR-1 and NDM-5 in <em>Escherichia coli</em> isolated from a colonization case of inpatient
... bla NDM-5 and mcr-1 has been reported in infection cases from specimens such as blood- stream, urinary tract, kidney, bile, and liver infections, this study is the first to report such an occurrence from a ...
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Emergence of New Delhi Metallo-β-Lactamase (NDM-5) in Klebsiella quasipneumoniae from Neonates in a Nigerian Hospital
... In conclusion, we describe the occurrence of clonal (ST476) NDM-5-producing K. quasipneumoniae subsp. similipneumoniae isolates in Africa with an IncX3-type plasmid highly similar to the plasmids found in ...
10
PubMedCentral-PMC5487671.pdf
... Plasmid characterization on CR Kp-1 and CR Kp-2 isolates, as well as on transformants, was performed by PCR-based replicon typing using the PCR-based replicon typing kit (Diatheva, Fano, PU, Italy) following the ...
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Detection and characterization of a clinical <em>Escherichia coli</em> ST3204 strain coproducing NDM-16 and MCR-1
... bla NDM-16 and mcr-1 genes were located on an ~65 kb plasmid and an ~80 kb plasmid, ...bla NDM-5 -harboring and mcr-1-harboring plasmids in ...coproduces NDM-16 and MCR-1. In addition, we ...
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Dissemination of the blaNDM-5 Gene via IncX3-Type Plasmid among Enterobacteriaceae in Children
... study characterized ST167 and ST617 as sister clades with respect to ST10, with ST617 emerging as a nested clade from a single outlying ST167 genome (27). The study also indicated that lineage-specific alterations in ...
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Dissemination of blaNDM-5 gene via an IncX3-type plasmid among non-clonal Escherichia coli in China
... Pulsed-field gel electrophoresis (PFGE) was performed to analyse the clonal relatedness of the NDM-5 producing E. coli isolates according to the previous study [15]. Briefly, the isolates were digested by ...
9
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANIOUS ESTIMATION OF SOFOSBUVIR AND DACLATASVIR IN BULK AND PHARMACEUTICAL FORMULATION BY RP- HPLC
... solutions: 5 tablets were weighed and the average weight of each tablet was calculated, then the weight equivalent to tablet was transferred into a 100 ml volumetric flask, 50ml of diluents was added and sonicated ...
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CALORIMETRIC DETERMINATION OF CEFTRIAXONE AND SULBACTAM IN INJECTION DOSAGE FORM
... Effect of BCG concentration (Method B) The optimum Bromo cresol green concentration on its reaction with sulbactam was studied by adding various volumes (0.5-2ml) of 0.4%Bromocresol green to a fixed concentration of ...
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COMPARATIVE STUDY THE MINERAL CONTENT OF SIDAT FISH (ANGUILLA MARMORATA (Q.) GAIMARDAND ANGUILLA BICOLOR) FROM LAKE POSO CENTRAL SULAWESI
... The mineral content in weight 0.5 kg and 3 kg has no difference. Both of type of Eel fish has the same constituent. A. marmorata has no Zinc (Zn) and Iodine (I). While A. bicolorhas no Calsium (Ca) and Sodium (Na). The ...
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PHARMACOVIGILANCE SYSTEM IN USA AND WHO
... DISCUSSION: Many serious drug adverse events (AEs) only manifest well after regulatory approval. Therefore, the development of signaling methods to use with post-approval AE databases appears vital to comprehensively ...
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CURRENT TRENDS IN STANDARDIZATION OF HERBAL FORMULATIONS IN AFRICA
... It is obvious that the content is the most difficult one to assess, since in most herbal drugs the active constituents are unknown. Sometimes markers can be used which are, by definition, chemically defined constituents ...
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REGULATORY REQUIREMENTS FOR REGISTRATION OF MEDICAL DEVICES IN SOUTH AFRICA
... submitted through the office of the Registrar of Medicines for consideration by the MCC. For a medical device or IVD to be included in the register, the Council must [r] ...
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EVALUATION OF ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF THE NOVEL DERIVATIVES OF 1, 3, 4-OXADIAZOLE IN EXPERIMENTAL ANIMAL MODELS
... Synthesis, antioxidant, and anti- inflammatory activity of morpholine mannich base of AMACs ((2e, 6e)-2- ({4-hydroxy-3- [morpholin-4-yl-) methyl] phenyl} methylidene)-6- (phenylmethylidene) cyclohexan-1- one) and its ...
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FOOD VIGILANCE SYSTEM IN UNITED STATES
... Implementation of HACCP is the responsibility of food producers, processors, distributors, and consumers. The role of government is to ensure that HACCP programs are properly implemented throughout the food supply ...
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