Nerve regeneration
The role of neural precursor cells and self assembling peptides in nerve regeneration
... facial nerve as well as CN9-12 can result in an array of debilitating conditions ranging from facial deformity to swallowing difficulties, dysphonia, to airway ...
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Synthetic conduits and growth factors for improved peripheral nerve regeneration
... peripheral nerve surgery using microsurgical techniques, the functional outcome) is not always ...the nerve stumps. In clinical practice today, an autologous nerve graft is considered the surgical ...
174
Peripheral nerve regeneration on fibronectin fibre substrates
... Peripheral nerve injuries commonly result in a surgically irreducible gap and represent a serious problem in ...autologous nerve grafts are the most effective means of promoting axonal regeneration ...
311
Schwann like cells seeded in acellular nerve grafts improve nerve regeneration
... for nerve injury. Some groups have supplemented acellular nerve grafts with cultured SCs ...treat nerve injures is rare, even obsolete, due to the dis- advantages, such as limited resources, ...
11
Nerve tissue engineering using blends of poly(3-hydroxyalkanoates) for peripheral nerve regeneration
... Peripheral nerve injuries (PNI) affect about ...in nerve damage with gaps of more than 5mm, treatment is most commonly attempted using autologous nerve graft repair [4, ...When nerve damage is ...
31
Use new PLGL-RGD-NGF nerve conduits for promoting peripheral nerve regeneration
... synthetic nerve conduits to bridge the gaps between the proximal and the distal nerve stumps for promoting nerve ...available nerve conduits, such as Neurotube (polyglycolic acid, PGA, ...
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Molecular Analysis of Target Specific Peripheral Nerve Regeneration
... peripheral nerve injury and are required for nerve regeneration in vivo (Werner et ...peripheral nerve regeneration have only been characterized in vivo in a few instances (Chen 2003; ...
153
Erythropoietin Promotes Functional Recovery and Enhances Nerve Regeneration after Peripheral Nerve Injury in Rats
... sciatic nerve transection in adult ...hances nerve regeneration after sciatic nerve transection in the ...axon regeneration is in agreement with the ...
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Role of Macrophage Migration Inhibitory Factor (MIF) in Peripheral Nerve Regeneration: Anti-MIF Antibody Induces Delay of Nerve Regeneration and the Apoptosis of Schwann Cells
... nerve regeneration. Extensive Schwann cell mitosis occurs in the distal nerve stump following nerve injury, but, as is the case with other proliferative tissues, actual cell numbers depend on ...
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Promotion of peripheral nerve regeneration of a peptide compound hydrogel scaffold
... The present study suggests that the SF16 peptide consists of a well-defined amino acid sequence that self-assembles under physiological conditions forming a fibrous scaffold within the nanoscale. Its honeycomb like 3D ...
9
Nerve growth factor activates autophagy in Schwann cells to enhance myelin debris clearance and to expedite nerve regeneration
... Autophagy is a conserved lysosomal degradation pathway that eliminates damaged organelles and pathological proteins to maintain intracellular homeostasis [17]. Accumulating evidence suggests that myelin debris clearance ...
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The Role Of Molecular Motors In Peripheral Nerve Regeneration
... sciatic nerve models lesions are introduced millimeters away from neuronal cell bodies (115), while in larval zebrafish – due to the smaller animal size – lesions are generated about 10-50 μm away from neuronal ...
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Effects of different doses of X-ray radiation on nerve regeneration after sciatic nerve injury in a rat model
... on nerve regeneration after peripheral nerve ...on nerve regeneration after sciatic nerve injury in ...of nerve regeneration were performed by using various ...
10
Knockout of TLR4 and TLR2 impair the nerve regeneration by delayed demyelination but not remyelination
... the nerve regen- eration following the sciatic nerve crush injury in both Tlr4 −/− and Tlr2 −/− mice was worse than the C57BL/6 mice and there was significant increase of the fiber debris remained in the ...
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Electro acupuncture on functional peripheral nerve regeneration in mice: a behavioural study
... sciatic nerve, “distal” ...peripheral nerve regeneration [10], no differences were reported between controls without needles and those having implanted needles without ...with nerve ...
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Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling
... improved nerve regeneration under fingolimod treatment, B- and T- lymphocyte deficient Rag1 −/− mice did not show an improvement of nerve regeneration, neither with fingoli- mod nor vehicle ...
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LRP receptors in a novel mechanism of axon pathfinding and peripheral nerve regeneration
... While there are many LRP1 and 2 ligands, I focused on a selection from those implicated in neuronal function: namely, Apolipoprotein E (ApoE), α-2 macroglobulin (α2M), transthyretin (TTR), vitamin D/vitamin D binding ...
278
Nerve regeneration in vascularized composite allotransplantation: current strategies and future directions
... peripheral nerve regeneration to facilitate motor and sensory reinnervation of donor ...enhance nerve regeneration and graft reinnervation, and functional outcomes are dependent on the ...
10
Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling
... in nerve growth factor depleted cultures ...after nerve injury [8], its mechanisms in terms of nerve regeneration and re-innervation are still ...
22
Immunophilin ligands in peripheral nerve regeneration
... lesioned nerve is seldom possible since clinicians tend to wait prior to making their diagnosis and plans for treatment ...for nerve regeneration studies, mostly there is a certain denervation time ...
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