neural crest
Snail2 controls mesodermal BMP/Wnt induction of neural crest
... Injection of snail2 antisense RNA, or snail2 or twist1 MOs, into one cell of 2-cell embryos leads to the loss of the mesodermal markers xbra, antipodean/vegT and myoD, an increase in the expression domain of the ...
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PTK7 recruits dsh to regulate neural crest migration
... the neural crest marker twist (D,F,H) or the midbrain-hindbrain marker engrailed ...the neural crest markers twist (J,K) or AP-2 ...cranial neural crest migration is marked by ...
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Establishing neural crest identity: a gene regulatory recipe
... premigratory neural crest into individual ...cranial neural crest requires a switch between type 1 cadherins [such as cadherin 1 (Ecad) and cadherin 2 (Ncad)] and type 2 cadherins (Cad7 and ...
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Jawsfest: new perspectives on neural crest lineages and morphogenesis
... the neural ectoderm (as is believed) but also the non-neural ectoderm undergo epithelial to mesenchymal transitions (EMT) in the embryonic head to give rise to migratory ...the neural crest ...
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A novel role for cardiac neural crest in heart development
... cardiac neural crest ablation results in hemodynamic alterations of the aortic arch arteries that subsequently cause abnormal ventricular function, then ablation of the arch arteries themselves should cause ...
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Trunk neural crest cells: formation, migration and beyond
... ABSTRACT Neural crest cells (NCCs) are a multipotent, migratory cell population that generates an astonishingly diverse array of cell types during vertebrate ...trunk neural crest has long ...
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Progenitors of the protochordate ocellus as an evolutionary origin of the neural crest
... proto-neural crest, then it would be possible for some features of the lineages to merge, resulting in a novel functional chimer- ical cell, such as the ...
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LSox5 regulates RhoB expression in the neural tube and promotes generation of the neural crest
... of neural crest cells, which express several neural crest markers, including Pax7, Slug, FoxD3, RhoB, Sox10 and ...of neural crest generation was best visualised in the ...
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A chemotactic model of trunk neural crest cell migration
... trunk neural crest cells leads to significantly reduced numbers of sympathetic neurons (Boer et ...trunk neural crest cells that move over long distances towards the dorsal aorta readout ...
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The diverse neural crest: from embryology to human pathology
... The embryological results that uncovered the paramount role of the NC cells in building various head tissues, together with other considerations, led Carl Gans and R. Glenn Northcutt (Gans and Northcutt, 1983) to develop ...
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Cell fate decisions during neural crest ontogeny
... of neural crest derivatives in the dorsal neural ...dorsal neural tube 6hr after microin- jection of the pCAGGS plasmid encoding green fluorescent protein ...dorsal neural tube opposite ...
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Matrigel supports neural, melanocytic and chondrogenic differentiation of trunk neural crest cells
... Trunk neural crest cells (TNCCs) were isolated from explanted neural tubes dissected at thoracic level (last 10 somites) from quail embryos at 20-25 somite ...explanted neural tubes were ...
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Ezh2 is required for neural crest derived cartilage and bone formation
... Fig. 1. Migration of NCCs to their target structures is not impaired by loss of Ezh2. (A-F) Wnt1-Cre-mediated ablation of Ezh2 results in loss of H3K27me3 in mouse E9.5 neural crest stem cells (NCSCs). To ...
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Neural crest cell autonomous roles of fibronectin in cardiovascular development
... The chemical and mechanical properties of extracellular matrices (ECMs) modulate diverse aspects of cellular fates; however, how regional heterogeneity in ECM composition regulates developmental programs is not well ...
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The neural crest cell cycle is related to phases of migration in the head
... Embryonic cells that migrate long distances must critically balance cell division in order to maintain stream dynamics and population of peripheral targets. Yet details of individual cell division events and how cell ...
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Neural crest specification by noncanonical Wnt signaling and PAR 1
... for neural crest specification To identify a potential noncanonical Wnt ligand responsible for NC specification, we searched for Wnt proteins that are expressed in close proximity to the NC ...
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Hypoxia promotes production of neural crest cells in the embryonic head
... the neural tube examining continuous emigration of neural crest cells and the competence to respond to DMOG at various ...of neural crest ...labelled neural crest cells ...
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Hoxa2 downregulates Six2 in the neural crest derived mesenchyme
... cranial neural crest, corresponding to the population that migrates to the second branchial arch (Prince and Lumsden, 1994; Nonchev et ...in neural crest cells expressing ...the neural ...
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Galectin 1 enhances the generation of neural crest cells
... SOX10+ neural crest (NC) cells from explanted neural ...(A) Neural tubes were isolated from ...(B,C) Neural tubes isolated from ...the neural crest marker genes Sox10, ...
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Essential role of AWP1 in neural crest specification in Xenopus
... The neural crest (NC) comprises a transient and multipotent embryonic cell population, which gives rise to a wide variety of cell types, including craniofacial cartilage, melanocytes, and neurons and glia ...
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