Neural lineage
Characterization of a Nerve Growth Factor-Inducible Cellular Activity That Enhances Herpes Simplex Virus Type 1 Gene Expression and Replication of an ICP0 Null Mutant in Cells of Neural Lineage
... Herpes simplex virus type 1 (HSV-1) ICP0 is required for efficient viral gene expression during lytic infection, especially at low multiplicities. A series of cellular activities that can substitute for ICP0 has been ...
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Single cell mechanical phenotype is an intrinsic marker of reprogramming and differentiation along the mouse neural lineage
... The stiffness of tissues and individual cells reflect their function. Load-bearing tissues, such as bone, cartilage or skeletal muscle, exhibit a high elastic modulus, other tissues that are not load bearing, such as ...
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Scaffolds for 3D in vitro culture of neural lineage cells
... of neural stem cells and neural cells in culture, the most widely used cell attachment molecule is laminin [38, 191], the primary component of the basement membrane in the ...
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Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders
... Human neural stem cell culture and differentiation GIBCO® hNSC (H9 hESC-Derived) was purchased com- mercially (N7800100, ThermoFisher ...StemPro® Neural Supplement (A1050901, Thermo- Fisher Scientific), 20 ...
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miR 125 potentiates early neural specification of human embryonic stem cells
... two neural crest markers SOX10 and SLUG (SNAI2 – Human Gene Nomenclature Committee) and of the two early epidermal markers CK18 and P63 (KRT18 and TP63, respectively – Human Gene Nomenclature Committee) ...
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N Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer
... marker neural cell adhesion molecule 1 (NCAM1) ...of neural differentiation character- ized by ganglion-like ...or neural markers (S100) but also contained cells that were positive for multiple ...
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Diverse roles for VEGF A in the nervous system
... the neural lineage contain reduced numbers of GnRH neurons, which are essential for gonad development and fertility ...the neural lineage or NRP1 in blood vessels contained normal numbers of ...
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In silico lineage tracing through single cell transcriptomics identifies a neural stem cell population in planarians
... epithelial lineage groups (ζNeoblasts, early epithelial and late epithelial) from ...the lineage- specific groups extended outward as distinct, non- overlapping ...our neural lineage ...
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Distinct functions of BMP4 during different stages of mouse ES cell neural commitment
... see also Fig. S1 in the supplementary material). Notably, we also performed a functional assay showing that the addition of BMP4 reduced the number of ESD-EpiSC colonies derived from ESCs (Fig. 5), and that the decreased ...
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Advances in stem cell therapy for spinal cord injury
... of neural lineage–spe- cific transcription factors ...in lineage fate rather than an induction of hybrid phenotypes, although the induced neuronal cells retain a small but detectable epigenetic ...
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Cell intrinsic and cell extrinsic cues regulating lineage decisions in multipotent neural crest derived progenitor cells
... multipotent neural crest cells turned out to be difficult to maintain due to considerable cell death, with the exception of cell cultures treated with serum-containing ...non- neural cells and cells ...
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Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus.
... the neural crest lineage, GSK3 is thought to have multiple sequential roles beginning with a requirement in patterning of the dorsal axis 19–21 ...frog, neural crest-specific GSK3 targets include the ...
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Drosophila intermediate neural progenitors produce lineage dependent related series of diverse neurons
... Fig. 1. Targeting Drosophila type II NBs for twin-spot clonal labeling. (A) Schematic illustration of the serial recombinase-dependent transgene activations via excision of the corresponding stop cassettes, enabling a ...
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Continuous live imaging of adult neural stem cell division and lineage progression in vitro
... example lineage tree exhibiting an asymmetric cell division (cell #2) generating neurogenic TAPs and a progenitor (cell #3) giving rise to cells with astroglial morphology (cells #4 and 5) (see also Movie 6 in the ...
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Progenitors of the protochordate ocellus as an evolutionary origin of the neural crest
... to neural crest evolution. Amphioxus does not have neural crest cells or any other cells delaminating from the dorsal neural tube or adjacent non-neural ...of neural crest gene regula- ...
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Sox10- Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytes
... Sox10 is a well-known marker of neural crest stem cells (NCSCs), along with slug, snail, and p75 [35,36]. There have been numerous reports recently of NCSCs surviving in a wide range of tissues through the entire ...
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Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells
... during neural induction and neuro- ...and neural cells takes place and how immune system reg- ulates nervous system in both physiological and pathological conditions [14, 59, ...glial lineage ...
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Phenotypic Differences between Asian and African Lineage Zika Viruses in Human Neural Progenitor Cells
... to neural cells due to their passage history in mouse brain tissues (18) and that the 4-aa deletion in the E protein of these viruses contributes to the observed ...African lineage ZIKV ...Asian ...
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Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development
... reduces neural stem cell self-renewal during CNS devel- opment [31], whereas loss of Ezh2 function in the develop- ing cortex results in reduced self-renewal and alterations in developmental timing ...
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Transient accumulation of 5 carboxylcytosine indicates involvement of active demethylation in lineage specification of neural stem cells
... 5-Methylcytosine (5mC) is an epigenetic modi- fication involved in regulation of gene activity during differentiation. Tet dioxygenases oxidize 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and ...
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