NF-kappaB (NF-κB)
Sneaking ligands inhibiting NF-kappaB activation selectively in endothelial cells improve experimental arthritides
... factor kappaB (NF-kappaB) pathway is related to the pathogenesis of several inflammatory autoimmune diseases including rheumatoid arthritis ...of NF-kappaB, a key regulator of ...
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TLR9 signaling activation at different stages in colorectal cancer and NF-kappaB expression
... Results: The result showed that the high expression of TLR9 was correlated with tumor poorly differentiation, invasion and liver metastasis, the abnomal increasing levels of CEA in blood. With the signal activation, the ...
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Bee venom ameliorates lipopolysaccharide-induced memory loss by preventing NF-kappaB pathway
... astroglial NF-kappaB following systemic in- flammation by LPS (10 mg/kg) was associated with brain cell and microvasculature injury in the sub-region of the hippocampus which ultimately likely results in ...
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Regulation of an essential innate immune response by the p50 subunit of NF kappaB
... of NF-kappaB complex, we provide data demonstrating that increased expression of the p50 subunit of NF-kappaB directly results in the downregulation of LPS-induced TNF ...
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Aberrant NF kappaB expression in autism spectrum condition : a mechanism for neuroinflammation
... when NF-κB becomes aberrantly active, has the potential to produce chronic or excessive inflammation associated with several inflammatory diseases (Pahl, ...that NF-κB plays a key role in Alzheimer’s ...
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The enhanced expression of death receptor 5 (DR5) mediated by HBV X protein through NF kappaB pathway is associated with cell apoptosis induced by (TNF α related apoptosis inducing ligand) TRAIL in hepatoma cells
... Pervious researches showed that the expressions of DR4 and DR5 were mediated by different pathways such as JNK pathway and NF-kappa B (NF-κB) pathway [16–19]. We measured the phosphorylation levels of JNK ...
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Low nuclear body formation and tax SUMOylation do not prevent NF kappaB promoter activation
... Tax-induced NF-κB activation appears to contradict our previous findings showing that fusion of SUMO-1 to lysine mutants restored their NF-κB ...the NF-κB activity of some but not all lysine Tax ...
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Inhibition of astroglial NF-kappaB enhances oligodendrogenesis following spinal cord injury
... Based on our previous findings of a reduced lesion vol- ume, increased white matter preservation and associated improvements in locomotor function 8 weeks following moderate contusion to the thoracic spinal cord in mice ...
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The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF kappaB activation
... ATM and NEMO physical associate with each other In the next step of nucleus to cytoplasm NF-κB activa- tion, NEMO associates with activated ATM and ATM phosphorylates NEMO to promote its ubiquitin- dependent ...
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Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB
... The mechanisms contributing to the potentiation of apoptosis by genistein pretreatment and combination treatment were evaluated in the A2780 and C200 cells. PARP cleavage was determined in A2780 and C200 cells that were ...
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Inhibition of NF-kappaB transcriptional activity enhances fucoxanthinol-induced apoptosis in colorectal cancer cells
... plus NF- κ B inhibitor combin- ation (which led to a strong induction of ...or NF- κ B inhibitor at the concentrations used in this study do not show strong ...Thus, NF-κB activation by FxOH is ...
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Combined effects of 17-DMAG and TNF on cells through a mechanism related to the NF-kappaB pathway
... TNF, NF-κB is activated through RIP-mediated activation of IκB kinase (IKK) and then released, allowing for its translocation into the nucleus and activation of its target genes ...of NF-κB, such as Bcl-xL, ...
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MANGIFERA INDICA L. EXTRACT MODULATES NF-KAPPAB SIGNALING PATHWAY IN THE COURSE OF ACTIVATION-INDUCED T CELL DEATH
... that NF- κB is activated by oxidative signals produced during TCR ...of NF-κB in the protective effect demonstrated by ...of NF-κB ...modulate NF-κB ...
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Mechanisms of Non-canonical NF-kappaB Regulation
... classical NF- κ B pathway in negatively regulating basal non-canonical NF- κ B ...non-canonical NF- κ B pathway by the classical IKK complex in human ...non-canonical NF- κ B signaling has ...
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NF kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy
... on NF- B expression in esophageal cancer ...caused NF- B activation in a dose-dependent ...increased NF- B DNA-binding activity at amounts of 300 M DCA at 2 hours ...of NF- B was ...
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Activation of transcription factor NF-kappaB by the Tat protein of human immunodeficiency virus type 1.
... Tat induces nuclear NF- k B binding activity in HL3T1 cells. The above-reported experiments have demonstrated that Tat delivery in HL3T1 cells determines a modification of protein- DNA interactions at the k B ...
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Efficient transcription and replication of simian immunodeficiency virus in the absence of NF-kappaB and Sp1 binding elements.
... the NF- k B element, which correspond to the novel enhancer element, are also uni- formly retained ...the NF- k B site containing this novel en- hancer ...
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Induction of AIDS by simian immunodeficiency virus lacking NF-kappaB and SP1 binding elements.
... Our results also allow some speculation on the possible role of NF-kB and Sp1 elements in replication in particular cell types and tissues and in tissue-specific disease manifestations (1, 7, 9, 20). The behavior ...
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Investigating the role of IKK epsilon in cancer-associated NF-kappaB activity
... by the inability of MyD88-deficient mice to respond properly to a variety of TLR ligands, namely LPS, peptidoglycan and bacterial CpG motifs [19, 34] Interestingly, analysis of MyD88-deficient cells in response to LPS ...
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Involvement of NF kappaB associated proteins in FGF mediated mesoderm induction
... Int J Dc lIiol 42 67 77 119981 67 O,iginal Arlirt" Involvement of NF KB associated proteins in FGF mediated mesoderm induction CAROLINE W BECK", DAVID J SUTHERLAND' and HUGH R WOODLAND Department of B[.] ...
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