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Non-small cell lung carcinomas

MicroRNA-148a suppresses proliferation and invasion potential of non-small cell lung carcinomas via regulation of STAT3

MicroRNA-148a suppresses proliferation and invasion potential of non-small cell lung carcinomas via regulation of STAT3

... Abstract: Lung cancer has the highest morbidity and mortality in the world, and non-small cell lung carcinomas (NSCLC) account for 80% of cases of lung ...NSCLC ...

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Original Article Relationship of Fas, FasL, p53 and bcl-2 expression in human non-small cell lung carcinomas

Original Article Relationship of Fas, FasL, p53 and bcl-2 expression in human non-small cell lung carcinomas

... 110 non-small cell lung carcinomas (NSCLCs) were investigated to evaluate their roles in pulmonary carcinogenesis and to examine the clinicopathologic significance of Fas expression ...

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Positive nuclear BAP1 immunostaining helps differentiate non- small cell lung carcinomas from malignant mesothelioma

Positive nuclear BAP1 immunostaining helps differentiate non- small cell lung carcinomas from malignant mesothelioma

... All 45 non-small cell lung cancer samples analyzed –32 adenocarcinomas and 13 SCC– stained positive for nuclear BAP1 (Table 1, Figure 1). Strong nuclear staining was detected in ~100% of the ...

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Relationship of the K-ras/c-mos Expression Patterns With Angiogenesis in Non-Small Cell Lung Carcinomas

Relationship of the K-ras/c-mos Expression Patterns With Angiogenesis in Non-Small Cell Lung Carcinomas

... c-mos Cytoplasmic and membranous immunoreac- tivity was considered to be evidence of c-mos ex- pression. As we have previously described, nuclear staining in the presence of cytoplasmic and/or mem- branous reactivity was ...

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Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung Carcinomas

Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung Carcinomas

... well-differentiated lung AdCs, immunostaining patterns of p27 and Ki-67 are similar, with expression mostly occurring in the periphery of tumor nodules, in cells possessing an increased proliferative ...

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Evaluation of Epidermal Growth Factor Receptor by Mutation Specific Immunohistochemistry in Non Small Cell Lung Carcinomas

Evaluation of Epidermal Growth Factor Receptor by Mutation Specific Immunohistochemistry in Non Small Cell Lung Carcinomas

... Lung Cancer has emerged as a common cancer in India and is a leading cause of cancer related mortality. Tuberculosis, tarring of roads, the 1918 influenza epidemic, anthracosis, and anthracosilicosis – are now ...

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Original Article Downregulation of ALDH1A1 expression in non-small cell lung carcinomas – its clinicopathologic and biological significance

Original Article Downregulation of ALDH1A1 expression in non-small cell lung carcinomas – its clinicopathologic and biological significance

... The largest tumor sections were cut from for- malin-fixed, paraffin-embedded tissue blocks. The sections were deparaffinized, rehydrated, and incubated with 3% hydrogen peroxide, fol- lowed by 5% goat serum to block ...

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CD10/NEP in non small cell lung carcinomas  Relationship to cellular proliferation

CD10/NEP in non small cell lung carcinomas Relationship to cellular proliferation

... The cell surface metalloproteinase CD10/neutral endopeptidase ...of small cell carcinomas of the lung (SCLC) and normal fetal bronchial epithelium, we evaluated the ...

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Genome-wide DNA methylation profiling of non-small cell lung carcinomas

Genome-wide DNA methylation profiling of non-small cell lung carcinomas

... in non-small cell ...paired lung tissue sample (y axis). (C) Raw reads from a lung sample (above panel) and its matching tumor sample (middle panel) in the position chr2:176,716,200 to ...

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Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

... carcinoma, 4 undifferentiated carcinomas and 1 large cell carcinoma) were evaluated. All the patients were diagnosed and treated at the Regina Elena Cancer Insti- tute, Rome, Italy. Patients underwent ...

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Case Report Parotid gland and cerebellum metastasis of lung cancer: a case report

Case Report Parotid gland and cerebellum metastasis of lung cancer: a case report

... Squamous cell carcinomas accounts for ap- proximately 30% of all non-small cell carcinoma of the lungs ...primary small-cell carcinoma [3-7] and adenocarcinoma [8]. ...

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Lung cancer cytology: potential pitfalls- a review

Lung cancer cytology: potential pitfalls- a review

... the lung and will eventually metastasize to the lymph nodes and other parts of the ...of lung cancer: squamous cell carcinomas, adenocarcinomas, small cell carcinomas, and ...

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Prognosis of ampullary cancer based on immunohistochemical type and expression of osteopontin

Prognosis of ampullary cancer based on immunohistochemical type and expression of osteopontin

... advanced non-small cell lung cancer [15], laryngeal and hypopharyngeal carcinomas [16], hepatocellular carcinoma [17], colorectal cancer [18], idiopathic pulmonary hypertension [19], ...

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Prognostic Role of miR 205 in Early Stage (T1N0) Non Small Cell Lung Cancer

Prognostic Role of miR 205 in Early Stage (T1N0) Non Small Cell Lung Cancer

... regulate cell differentiation, apoptosis, and ...several carcinomas, in- cluding non-small cell lung cancer (NSCLC); moreover, aberrant expression of miRNAs is significantly ...

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Original Article Downregulation of TMEM176A suppresses cell growth and proliferationin non-small cell lung cancer

Original Article Downregulation of TMEM176A suppresses cell growth and proliferationin non-small cell lung cancer

... 5% non-fat dry milk for 1h at room temperature, and probed with the corresponding primary anti- bodies, including anti-TMEM176A, CDK4, Cyclin D1, Bad, caspase-3 and PARP ...

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Prognostic value of angiopoietin 2 in non small cell lung cancer patients: a meta analysis

Prognostic value of angiopoietin 2 in non small cell lung cancer patients: a meta analysis

... 100 lung cancer patients (87 NSCLC) and then found that VEGF and Ang-2 showed a weak positive correlation; in addition, a higher Ang-2 level in patients may be useful for differential diagnosis, whereas there was ...

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Vaccines in Non Small Cell Lung Cancer

Vaccines in Non Small Cell Lung Cancer

... 80%. Non-small cell lung cancer stage IIIB and IV patients were enrolled between 2000 and 2002 by centers of Canada and the United Kingdom, including a total of 171 ...a non-significant ...

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Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer

Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer

... of lung and other cancers. Recent progress in the treatment of lung cancer with im- mune therapies reinforces the need to better understand host immune responses in the context of lung ...relatively ...

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Superior vena cava syndrome in a patient with locally advanced lung cancer with good response to definitive chemoradiation: a case report

Superior vena cava syndrome in a patient with locally advanced lung cancer with good response to definitive chemoradiation: a case report

... The patient was presented at the multidisciplinary thoracic oncology tumor board, and observation was recommended on the basis of absence of tumor progres- sion and presence of an adequate collateral venous sys- tem. Her ...

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FDG PET in the evaluation of response to nivolumab in recurrent non small cell lung cancer

FDG PET in the evaluation of response to nivolumab in recurrent non small cell lung cancer

... 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) is an effective tool for assessing treatment response and surveillance of disease recurrence; however, it sometimes shows increased FDG uptake at sites of ...

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