Notch signalling
"Notch Off": a perspective on the termination of Notch signalling
... nizes Notch signalling in the Drosophila nervous system, by downregulating the activity of a positive regulator of Notch, ...with Notch at the membrane (Hutterer and Knoblich, ...regulating ...
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Notch signalling stabilises boundary formation at the midbrain hindbrain organiser
... that Notch might be activated at the border of Lfng and Ser1 expression, we misexpressed mouse Lfng and analysed embryos for changes in chick Lfng expression using a probe that does not recognise the mouse Lfng ...
13
Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling
... aortic Notch signalling in CSL:venus transgenics, we quantified fluorescence intensity in a two somite length of the wall of the aorta just above the ...
10
Specification of vertebral identity is coupled to Notch signalling and the segmentation clock
... of Notch signalling and cyclic Lfng activity in the second step, potentially after cells have passed the determination ...and Notch signals in the anterior psm might set definitive rostral Hox ...
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The cytolinker Pigs is a direct target and a negative regulator of Notch signalling
... in Notch activity was already apparent in region 2b in the germarium, when germline cyst encapsulation normally commences ...Elevated Notch signalling in these early pre-stalk FCs could be ...
10
A novel reporter of notch signalling indicates regulated and random notch activation during vertebrate neurogenesis
... of Notch signalling, have made it difficult to monitor Notch activity and study its relationship to the behaviour of individual cells, as they progress through the cell cycle and undergo ...for ...
16
Wnt/Notch signalling and information processing during development
... not Notch-dependent genes (Kubo et ...Wnt signalling can be explained if Wnt acts on a pool of ‘stem cells’, which in normal tissue is small and embedded in the progenitors, most of which would be acting as ...
14
Notch signalling mediates reproductive constraint in the worker honeybee
... that Notch signalling activity decreases as the bees respond to the absence of QMP and initiate oogenesis ...to Notch signalling 46–48 ...that Notch signalling is downregulated ...
10
An investigation into how the cell cycle and the Notch signalling pathway regulate pronephrogenesis in Xenopus laevis
... the Notch signalling pathway, presumably regulated by Radical fringe, has not been ...of Notch-deficient mice (Conlon et ...the Notch signalling pathway by a similar mechanism to the ...
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Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling
... aortic Notch signalling in CSL:venus transgenics, we quantified fluorescence intensity in a two somite length of the wall of the aorta just above the ...
10
Mib Jag1 Notch signalling regulates patterning and structural roles of the notochord by controlling cell fate decisions
... in Notch signalling by knocking down two Su(H) proteins, [Su(H)1 and Su(H)2), which act downstream of Notch signalling (Zhang, ...Jag1-Notch signalling is required to establish ...
11
Interplay between FGF10 and Notch signalling is required for the self renewal of pancreatic progenitors
... It is noteworthy that untreated isolated pancreatic epithelia showed in vitro an outcome similar to that of the pancreas of mice deficient for different genes of the Notch pathway, or the pPdx1- Ngn3 mice. That ...
10
Delta Notch signalling controls commitment to a secretory fate in the zebrafish intestine
... Delta-Notch signalling plays a part in singling out the goblet cells, and perhaps other minority cell types, for a fate different from that of their ...
12
Notch signalling is required for both dauer maintenance and recovery in C elegans
... that Notch signalling might be involved in some aspect(s) of this developmental ...whether Notch might play a more physiological role that may affect dauer formation, maintenance and/or ...the ...
10
Cell autonomous integrin control of Wnt and Notch signalling during somitogenesis
... to Notch signalling, at least in anterior somites (Jülich et ...other signalling pathways. Segmentation critically depends on both Notch and Wnt signalling, which are required in the ...
11
Notch signalling coordinates tissue growth and wing fate specification in Drosophila
... secreted signalling molecules, Wingless and the EGF receptor ligand Vein. Notch signalling is involved in the determination of a variety of cell fates, including growth and cell ...of Notch is ...
7
Novel genes upregulated when NOTCH signalling is disrupted during hypothalamic development
... Furthermore, Notch inhibition during this period was associated with an increase in the number of neurons and a loss of the scattered neurons in the rostral hypothalamus (Figure ...of Notch ...
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Cell movements controlled by the Notch signalling cascade during foregut development in Drosophila
... the Notch receptor occurs in cells that are adjacent to the ligand-expressing cells (Heitzler and Simpson, ...for Notch signalling and cell movement, which would be consistent with our observation ...
9
Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart
... the Notch pathway in Tg(UAS:NICD);ET33-mi60a hearts resulted in a reduced number of filopodia-like protrusions ...for Notch in endocardial ...after Notch signalling manipulation ...of ...
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Dynamic Notch signalling regulates neural stem cell state progression in the Drosophila optic lobe
... The Notch signalling pathway is a key regulator of cell-cell communication required for stem cell self-re- newal and differentiation ...to Notch on a neighbouring cell, the Notch intracellular ...
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