nucleotide insertion
A novel nucleotide insertion in S gene of hepatitis B virus in a chronic carrier
... acid insertion, and clone sequencing confirmed the mixture of variant HBsAg and wildtype ...12-nucleotide insertion, 15 clones had identical AGAACAACACAA insertion between nucleotide ...
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Diversification of the Ig Variable Region Gene Repertoire of Synovial B Lymphocytes by Nucleotide Insertion and Deletion
... mutations, nucleotide insertion and deletion also alter gene ...identified nucleotide insertions and deletions (3 to 12 bp) at a frequency of ...
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Cytopathogenicity of a pestivirus correlates with a 27-nucleotide insertion.
... the insertion identified in the genome of CP7 is located far up- stream from the corresponding genomic ...9-aa insertion is involved in the generation of NS3 in CP7-infected ...
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A three-nucleotide insertion in the H stem-loop of the 5' untranslated region of Theiler's virus attenuates neurovirulence.
... The kinetics of viral RNA and protein synthesis and virus production in BHK-21 cells were slower for the mutant chimera [Chi-VLIN668J than for Chi-VL; however, the final virus yields wer[r] ...
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Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion
... (a,b) Nucleotide dependence of FRET observables associated with the formation of ternary complexes of wt KF (a) and E710A (b) in the presence of ...the nucleotide-concentration-dependent FRET observables ...
11
RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts.
... If the nucleotide sequence of clones containing two nontemplated G residues is translated, it is found to yield a reading frame large enough to encode the mumps virus P protein.. Further[r] ...
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Enhanced competitiveness of tomato bushy stunt virus defective interfering RNAs by segment duplication or nucleotide insertion.
... These data establish that DI-RI containing a segment duplication is more competitive than either of the previously characterized smaller DI RNAs DI-73 and DI-72.. Transition of DI-73 to [r] ...
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Phellinus noxius: molecular diversity among isolates from Taiwan and its phylogenetic relationship with other species of Phellinus based on sequences of the ITS region
... ITS nucleotide variation also revealed the possible division into three distinct groups based on sequence length among the 91 isolates of ...single nucleotide polymorphisms, single nucleotide ...
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Structural features in the Rous sarcoma virus RNA stability element are necessary for sensing the correct termination codon
... Figure 4 A premature termination codon inserted within the RSE at position 2685 underwent decay when readthrough of the gag stop codon was forced. A. Schematic of stop codon locations within the RSE. Premature ...
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Molecular Epidemiology of Respiratory Syncytial Virus Infections among Children with Acute Respiratory Symptoms in a Community over Three Seasons
... Our phylogenetic analysis revealed that genotype GA5 of subgroup A was predominant in the 2001-2002 and 2003-2004 seasons, while a new genotype of subgroup B, which featured a 60-nucleotide insertion in the ...
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Development of a CRISPR/Cas9 genome editing toolbox for Corynebacterium glutamicum
... Additional file 1: Figure S1. PCR verification of ldhA deletion using CRISPR/Cas9 and the two-step electrotransformation strategy in Corynebacterium glutamicum SL4. M, DNA marker; –, wild-type control; 1–20, twenty ...
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Insertion/Deletion and Nucleotide Polymorphism Data Reveal Constraints in Drosophila melanogaster Introns and Intergenic Regions
... Hanke et al. 1999) and—in some cases—their pre- A broad range of PDB estimates is found in the litera- mRNA secondary structure can affect gene expression ture. In a survey of sequence length diversity in the Adh (Chen ...
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Employing transposon mutagenesis to investigate foot and mouth disease virus replication
... Figure S4. Location of the replication-competent 3D450 insertion. Cartoon of the 3D pol crystal structure showing the conventional right-hand front view (a) and rotated ~ 180 (b). Motif C containing the active ...
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Nucleotide sequence of a full-length human endogenous retroviral segment.
... The nucleotide sequence of a second human retroviral clone 4-14 was determined in the same region data not shown, and both the 12-amino-acid insertion and the same 11-of-14 deduced amino[r] ...
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The promoter for the late gene encoding Vp5 of herpes simplex virus type 1 is recognized by cell extracts derived from uninfected cells.
... Only two nucleotide changes, a T-to-C transition and an insertion of a G, in the probe sequence were discovered upon comparison of these sequence data from +71 from the SmaI site: DISCUS[r] ...
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Substitutions in the protease (3Cpro) gene of poliovirus can suppress a mutation in the 5' noncoding region.
... In an attempt to identify viral proteins that might interact with the 5'NC segment of the RNA, we isolated revertants from a mutant 5NC-11 that has a 4-base insertion at nucleotide 70 an[r] ...
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Molecular and biological properties of BK virus-IR, a BK virus variant isolated from a human tumor.
... To better characterize the genome of BKV-IR, we carried out a nucleotide sequence analysis of the regions of BKV-IR DNA containing the insertion and the deletion and compared them with t[r] ...
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A +2138InsCAGACC Polymorphism of the Melanocortin Receptor 3 Gene is Associated in Human with Fat Level and Partitioning in Interaction with Body Corpulence
... 2138 insertion allele showed higher mean values than the heterozygotes and the wild-type homozygotes ( 4% %FAT and 3 kg to 4 kg ...2138 insertion allele had lower mean values ( 4% %FAT, 4 to 5 kg FM) than ...
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GenomeGems: evaluation of genetic variability from deep sequencing data
... sequencing and re-sequencing [8,9]. This advancement possesses computational challenges for base calling, read alignment, genome assembly, mutation detection as well as data visualization [3,10-12]. Currently, a variety ...
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Indel sensitive and comprehensive variant/mutation detection from RNA sequencing data for precision medicine
... Somatic mutations are a hallmark of a tumor and inherited mutations cause certain genetic disorders. Characterization of these mutations and exploration of their clinical rele- vance constitute a critical part of ...
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