Olfactory receptor
Pre and postembryonic development, growth and turnover of olfactory receptor neurones in crayfish antennules
... The antennules, second antennae and small mandibles can be identified as single lobe-like appendages in the head region of embryos that have reached 40–50 % development. The antennules are unsegmented and are nearly ...
10
Voltage and Ca(2+) gated currents in zebrafish olfactory receptor neurons
... Recently, our understanding of the physiology, biochemistry and molecular biology of olfaction has progressed rapidly. Genes coding for putative olfactory receptor proteins have been cloned (Buck and Axel, ...
12
Olfactory receptor neurons express olfactory marker protein but not calpain 5 from the same genomic locus
... [4–12]. Olfactory marker protein (OMP) is highly expressed in mature olfactory receptor neurons (ORNs) and has been used as a powerful marker to investigate the physiology of olfaction ...
6
Intracellular messenger mediated cation channels in cultured olfactory receptor neurons
... pupal olfactory receptor neurons from the antennae of male Manduca sexta respond to their species-specific sex pheromone by opening cation ...cultured olfactory neurons that promote inward currents ...
23
Olfactory receptor genes cooperate with protocadherin genes in human extreme obesity
... in olfactory receptor genes on chromosome 1q and rare predicted damaging variants in the protocadherin (PCDH) beta-cluster genes on chromosome 5q31, reported in our previous work, co- localize in subjects ...
12
Extensive copy-number variation of the human olfactory receptor gene family.
... As much as a quarter of the human genome has been reported to vary in copy number between individuals, including regions containing about half of the members of the olfactory receptor (OR) gene family. We ...
53
Update on the olfactory receptor (OR) gene superfamily
... Vertebrate olfactory receptor (OR) genes represent a category of G-protein-coupled receptors (GPCRs) that contain seven transmembrane a -helical domains and function in the reception of innumerable odour ...
11
Natural odor ligands for olfactory receptor neurons of the female mosquito Aedes aegypti: use of gas chromatography linked single sensillum recordings
... Female Aedes aegypti are vectors of dengue and yellow fever. Odor volatiles are the predominant cues that drive the host-seeking behavior of Ae. aegypti. Odorant molecules are detected and discriminated by ...
8
Identification and Knockdown of the Olfactory Receptor (OrCo) in Gypsy Moth, Lymantria dispar
... The gypsy moth, Lymantria dispar, is an important economic pest that causes large-scale damage to forests worldwide. Because of its important role in initiating and controlling insect behavior, ol- faction—and ...
9
Receptor expression and sympatric speciation: unique olfactory receptor neuron responses in F1 hybrid Rhagoletis populations
... in receptor expression at the periphery could allow a shift in the agonistic/antagonist properties of a compound (Baker et ...2006). Olfactory receptor neurons expressing one type of olfactory ...
13
Predicting olfactory receptor neuron responses from odorant structure
... With these notes of caution, one might speculate that binding of odor molecules is achieved through different receptor-ligand interaction mechanisms at each OR. For example, our study suggests that ab2A is ...
10
Electrical responses to Chemical Stimulation of Squid Olfactory Receptor Cells
... Some indirect evidence for localization of Na + channels to discrete regions on the squid receptor cell comes from experiments with TTX, a chemical that blocks Na + currents and action p[r] ...
20
Novel natural ligands for Drosophila olfactory receptor neurones
... Linking electrophysiology with gas chromatography (GC) (Arn et al., 1975; Wadhams, 1982) can solve this shortcoming. GC–electrophysiology, in particular GC linked with recordings from single ORNs, so called GC–single ...
10
The human olfactory receptor repertoire
... Olfactory receptors have short (approximately 25-30 amino acids) extracellular amino termini that do not have homology to traditional cleavable leader peptides. A strongly conserved stretch of unknown functional ...
12
The Evolution of Mammalian Olfactory Receptor Genes
... To test whether this gene count was artificially low due to the use of a probe from a different species, four replicate Southern blots of dog and human genomic DNA were hy[r] ...
11
Revealing cellular and molecular complexity of the central nervous system using single cell sequencing
... mammalian olfactory system is capable of detecting and discriminating between a tremendous number of odorants by following the “ one neuron – one receptor ” ...rule. Olfactory sensory neurons (OSNs) ...
11
Long-Distance Interferon Signaling within the Brain Blocks Virus Spread
...  receptor (27), a gift of ...the olfactory receptor neurons, the selective toxin methimazole (50 mg/kg of body weight) was given intraperitoneally to 129Bl/SJ adult male mice (Jackson Laboratory), ...
10
Fine structure of the dorsal organ of the house fly larva (Musca domestica L.)
... As a hypothesis, we assume that the dome of the dorsal organ is an olfactory receptor while the unbranched receptors having a pore opening to the exterior are involved in contact chemo- [r] ...
18
Antennal expression pattern of two olfactory receptors and an odorant binding protein implicated in host odor detection by the malaria vector Anopheles gambiae
... and olfactory receptors ...these olfactory proteins, as well as the ubiquitous odorant receptor hetero- merization partner AgOR7, in the thirteen flagellomeres (segments) of female and male an- ...
13
Human infant olfaction : responses to food odours measured by brain electrical activity mapping (B E A M )
... As with all sensory systems, structure subserves function and one of the nasal cavity's functions is to bring inspired air and odorants into contact with olfactory receptor cells... airf[r] ...
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