omics approaches
Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea
... by omics techniques ...and omics approaches have shown relatively limited success in improving pro- duction of important natural products at industrial ...
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OMICs approaches-assisted identification of macrophages-derived MIP-1γ as the therapeutic target of botanical products TNTL in diabetic retinopathy
... multiple OMICs approaches to identify the novel therapeutic target in the treatment of diabetic retinopathy by a herbal product Tang-Ning- Tong-Luo ...
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Early detection and personalized treatment in oral cancer: the impact of omics approaches
... These omics approaches will also play an important role in understanding relapses at the primary site after resection, distant metastasis and the development of second primary ...
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Evaluating the antidiabetic effects of Chinese herbal medicine: Xiao Ke An in 3T3 L1 cells and KKAy mice using both conventional and holistic omics approaches
... Methods: The antidiabetic effect of XKA was first investigated in 3T3-L1 cells to study the effect of XKA on adipogenesis in vitro. Oil Red O staining was performed to determine the lipid accumulation. The intracellular ...
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Advancing functional and translational microbiome research using meta-omics approaches
... omics approaches would be helpful in predicting the outcomes of drug treatment or guiding the usage of drugs. Many clinically prescribed drugs can be metabo- lized by the gut microbiome and/or modulate gut ...
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Integrated Meta-omics Approaches To Understand the Microbiome of Spontaneous Fermentation of Traditional Chinese Pu-erh Tea
... ABSTRACT The microbiome in fermentation has direct impacts on the quality of fermented foods and is of great scientific and commercial interest. Despite consider- able effort to explain the microbial metabolism associated ...
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Using omics approaches to understand pulmonary diseases
... DNA sequence variation is known to cause, or confer risk for, various rare and common diseases, and genetic testing is increasingly being integrated into medical practice [18, 19]. Starting in 2005, as initial cataloging ...
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Multi omics approaches to disease
... integrative omics approach often relies on a “holistic” view, which attempts to interrogate a suffi- ciently large number of individuals and incorporate the many sources of variability into statistical ...of ...
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Using single-cell multiple omics approaches to resolve tumor heterogeneity
... One example of the SCBC method for single-cell chip- based proteomic investigation first heavily dilutes a FACS enriched population before loading them into micro- chambers. Wei et al. used a phosphoproteomic antibody ...
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The ReFuGe 2020 Consortium: using "omics" approaches to explore the adaptability and resilience of coral holobionts to environmental change
... Human-induced environmental changes have been linked directly with loss of biodiversity. Coral reefs, which have been severely impacted by anthropogenic activities over the last few decades, exemplify this global problem ...
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Applications of omics approaches to the development of microbiological risk assessment using RNA virus dose–response models as a case study
... how omics data and the techniques used to generate and analyse such data can be used to improve and/or complement MRA, to identify where barriers may exist to the incorporation of omics data into MRA, and ...
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The potential of omics approaches to elucidate mechanisms of biodiesel-induced pulmonary toxicity
... that omics screens offer, policy makers could be provided with a more detailed understanding of how the different particles impact the lungs, and whether some cause more diverse toxicities than ...hypothesis-led ...
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Omics in Aid of Host-pathogen Interaction Studies: A Bacterial Perspective
... of omics-based strategies are key for the discovery of mechanisms steering bacterial virulence and ...advancements, omics approaches still have significant limitations when applied to study pathogens ...
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What can an ecophysiological approach tell us about the physiological responses of marine invertebrates to hypoxia?
... -omics approaches, have highlighted the major challenges of knowing what we can take from the data they generate and, in particular, making sense of the transcriptome (Feder and Walser, 2005; Rupert, 2008; ...
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Machine learning and systems genomics approaches for multi-omics data
... multi-omics approaches such as genomics, proteomics, metabolomics, and epigenomics, we are able to employ materials or devices that can interact with bio- logical systems at the molecular level and then ...
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Gut microbiome-host interactions in health and disease
... Metagenomic approaches are not just restricted to the analysis of microbial genomes. A more novel area of work relates to the analysis of the interaction of the gut microbiome with gut parasites, viruses, yeasts ...
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Computational dynamic approaches for temporal omics data with applications to systems medicine
... temporal omics data sets that involve various most updated biomedical challenge questions ...multitask approaches, which combines non- linear regression, multiview learning, multitask learning and Bayesian ...
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Translational Approaches In Cardiovascular Diseases by Omics
... "Omics" are technologies that make it possible to measure, compare or identify hundreds of molecules within a single sample, in a very short time, with a big field of view. These interdisciplinary fields ...
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Integrative Approaches to Reconstruct Regulatory Networks From Multi-Omics Data: A Review of State-of-the-Art Methods
... genomics approaches, various strategies can be adopted to perform a powerful integrative analysis without relying on a single best approach when applied to heterogeneous ...integration approaches provide a ...
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OMICS in Molecular Biology
... A major principle and guiding tool for the food safety assessment of genetically engineered (GE) crops is the concept of “substantial equivalence” according to principles outlined in OECD, 2006 and FAO. GE crop-derived ...
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