One-Pot Three-Component Reaction
A facile and efficient One pot Three Component Reaction (Kabachinik Fields Reaction) for the Synthesis of Novel α Aminophosphonates by 1, 4 Dimethylpiperazine as a new catalyst
... the one-pot three component reaction of equimolar quantities of 4-amino-N-2-thiazolyl-benzenesulfonamide (Sulfathiazole) (1), diethyl/dibutyl phosphites (2) and various aldehydes (3a-n) ...
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An Efficient Synthesis of Pyrido[2,3 d]pyrimidine Derivatives via One Pot Three Component Reaction in Aqueous Media
... Pyridopyrimidine and its derivatives have been studied due to a variety of chemical and biological significance. The importance of pyridopyrimidines as biologically ac- tive compounds includes their use as antibacterial ...
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Ionic liquid mediated a facile and convenient synthesis of new selanyl tetrazoles via one pot three component reaction
... One of the main challenges in medicinal chemistry is the design and synthesis of biologically active molecules. Multi-component reactions (MCRs) have emerged as a powerful tools in the synthesis of diverse ...
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One pot three component synthesis of chromeno[4,3 d ]pyrimidinone derivatives
... the One-pot three-component reaction of salicylaldehyde 1,3-dicarbonyl compounds and 2-Aminobenzimidazole in the presence of catalytic amounts of piperidine in acetic acid led to a ...
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Synthesis of benzo[f]chromeno[3,4-b]quinoline-6-ones and chromeno[3,4-b]quinoline-6,11-diones via one-pot three-component tandem Knoevenagel–Michael reaction catalyzed by n-Tetrabutylammonium tribromide
... report one-pot three-component reaction for synthesising benzo[f]chromeno[3,4- b]quinoline-6-one derivatives through tandem Knoevenagel-Michael reaction involving ...
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Application of tris (trihexyltetradecylphosphonium) gadolinium hexachloride as magnetically recoverable catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones in solvent-free conditions
... the one-pot multi-component synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives has been developed by one pot three component reaction of various ...
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Vol 2, No 11 (2013)
... efficient one-pot three-component reaction of benzaldehyde, barbituric acid and meldrum's acid for the synthesis of 5-phenyl-5,6-dihydro-1H-pyrano[2,3-d]pyrimidine-2,4,7(3H)-trione ...
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One-pot three-component synthesis of spirooxindoles catalyzed by nano Ag/kaolin
... convenient method for the synthesis of spiro[4H- pyran-3,3'-oxindoles]. Our investigation began with the evaluation of nano Ag/kaolin as a catalyst in the reaction of 5-bromoisatin (1 mmol), malononitrile (1 ...
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Multicomponent One-Pot Synthesis and Biological Evaluation of Pyrano[2,3-C] Pyrazoles
... report one-pot synthesis of pyrano[2,3-c]pyrazole derivatives (4a-t) by three- component reaction, a scaffold from which a diverse range of other biologically important New Chemical ...
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One pot rhodium catalysed three component dehydrogenation route to fused and spiro-heterocycles
... were then added to the reaction vessel and heated to 110˚C for a further 16 hours which failed to provide the spirocyclic cycloadduct 4. Only staring materials were recovered, probably due to strong chelation ...
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A Rapid and Highly Effectual Protocol for the Synthesis of Bis-coumarins using Triethylaminium-N-sulfonic Acid Tetrachloroaluminate under Solvent-Free Conditions
... In this work, a rapid and highly effectual protocol for the synthesis of bis-coumarins has been developed. The one-pot quasi three-component reaction of aromatic aldehydes (1 eq.) with ...
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Bronsted base catalysed efficient one pot three component synthesis of dihydropyrimidinone derivatives
... Biginelli reaction is found to be one of the most recognized multicomponent reactions ...and one pot synthesis of dihydropyrimidinones were first observed by ...P.Biginelliinvolving ...
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One pot three-component synthesis of imidazole derivatives using NH3/NH4Cl
... Generally, the synthetic procedure involves stirring the mixture of Acenaphthene quinone (1mmol), aldehyde (1mmol) , ammonium acetate (5 mmol) and ammonium chloride ( 3 mmol) for 180 min at under reflux conditions. The ...
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Copper (I) iodide nanoparticles on polyaniline as a green, recoverable and reusable catalyst for multicomponent click synthesis of 1,4-disubstituted-1H-1,2,3-triazoles
... A one-pot procedure for the synthesis of 1,4-disubstituted-1H-1,2,3-triazole derivatives via the three component coupling reaction between terminal alkynes, benzyl halides/-halo ...
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One Pot Four Component Reaction for the Synthesis of Formazans in an Environmentally Benign Procedure Mediated by KHSO4
... the reaction of aryldiazonium salts with phenylhydrazones of aldehydes in basic medium and the second type is based on coupling of aryldiazonium ions with active methylene groups followed by Japp Klingermann ...
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One-pot and Three-Component Synthesis of isoxazol-5(4H)-one Derivatives in the presence of Citric Acid
... in one-pot, three-component condensation reaction at room temperature in excellent ...convenient reaction times, easy work-up, mild reaction conditions, and using of water ...
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Tandem Aldol-Michael reactions in aqueous diethylamine medium: a greener and efficient approach to dimedone-barbituric acid derivatives
... a three component; one-pot cyclocon- densation reaction of aromatic aldehyde, barbituric acid, and dimedone using aqueous diethylamine ...
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Pharmaceutical Chemistry and Chemical Science | Peer Reviewed
... reported one-pot synthesis of tetrasubstituted pyrrole 64 which involves a three-component reaction between α-hydroxyketones 61, malononitrile 63 and ammonium acetate 62 using tungstate ...
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SYNTHESIS OF SUBSTITUTED AZITIDINE DERIVATIVES VIA ONE POT THREE-COMPONENT (2Π+2Π) CYCLOADDITION REACTION UNDER ULTRASONIC IRRADIATION METHOD Pravin Chavan*, Shivaji Jadhav, Megha RaiDOWNLOAD/VIEW
... are one of the most important classes of natural products and exhibit a wide spectrum of biological and pharmaceutical properties including Antimicrobial [11-13], Antitubercular[14], Anticonvulsant[15], Anti- ...
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Development of an organo- and enzyme-catalysed one-pot, sequential three-component reaction
... In summary, we have shown that the combination of organo- and enzymic catalysis may be exploited in one-pot reactions with two carboncarbon bond formation steps. Crucially, it was possible to identify ...
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