Opsonized zymosan
Proton secretion by the sodium/hydrogen ion antiporter in the human neutrophil
... Both superoxide O° production and lysozyme release in cells stimulated with opsonized zymosan or concanavalin A was significantly inhibited in the absence of Na+, restored to normal with[r] ...
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The Chemiluminescence Response and Bactericidal Activity of Polymorphonuclear Neutrophils From Newborns and Their Mothers
... Cheiniluminescence (CL) was measured in the polmorphonuclear neutrophils (PMN) of 18 norlnal term infants, their mothers, and controls during phagocytosis of opsonized zymosan particles.[r] ...
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Regulation of human monocyte/macrophage function by extracellular matrix Adherence of monocytes to collagen matrices enhances phagocytosis of opsonized bacteria by activation of complement receptors and enhancement of Fc receptor function
... opsonized zymosan. Thus, the enhanced phagocytosis and killing of opsonized bacteria by collagen-adherent monocytes appear to be by regulation of the function of membrane CR and FcR, without apparent ...
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The origin of the chemiluminescence of phagocytosing granulocytes
... of opsonized zymosan emit light by a process that is inhibited by superoxide dismutase and ...both zymosan and oxidizing agent, suggesting that the oxidation of particle components is necessary for ...
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Enhancement of Neutrophil Function as a Result of Prior Exposure to Chemotactic Factor
... Exposure of human polymorphonuclear leukocytes (PMN) to chemotactic factor, as well as the migration of PMN through a 5-µm pore-size membrane, results in a PMN population with enhanced chemiluminescence, enhanced ...
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Priming of polymorphonuclear neutrophils by atrial natriuretic peptide in vitro
... In ischemia-reflow states of coronary artery disease, the activation of PMN precedes the initiation of tissue damage. Release of atrial natriuretic peptide (ANP) from myocytes occurs within minutes after the onset of ...
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Syk phosphorylation – a gravisensitive step in macrophage signalling
... (non-opsonized zymosan, LPS and curdlan) showed the same effect: the production of oxygen radicals during the oxidative burst is significantly diminished under microgravity ...
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Deficiency of a surface membrane glycoprotein (Mo1) in man
... erythrocytes coated with C3bi. This rosetting was totally inhibited by a mixture of anti-Mo1 and anti-C3b (the major fragment of C3) receptor antibodies but not by either antibody alone. Since monoclonal antibodies to ...
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Comparative study of neutrophil activation by chemiluminescence and flow cytometry.
... (unopsonized) zymosan yielding the half-maximal response was about 30- to 40-fold higher for CL than for FC (Table ...that zymosan activation of neutrophils as determined by FC was insensitive to ...
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Further characterization of NADPH oxidase activity of human polymorphonuclear leukocytes
... phagocytizing cells than in granules from resting cells. The drug phorbol myristate acetate, which affects the oxidative metabolism of the neutrophil like phagocytosis, was found to activate granule NADPH oxidase ...
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Human monocyte derived mucus secretagogue
... with opsonized zymosan or protein A- containing Staphylococcus aureus to examine whether factors might be released that were capable of stimulating mucous glycoprotein release from cultured human airways, ...
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Inflammation and enhanced nociceptive responses to bladder distension produced by intravesical zymosan in the rat
... Only a few validated animal models of visceral nocicep- tion exist (for review, see [8]). Those that have been vali- dated typically have used observations of animal posturing as well as reflex increases in arterial ...
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LOX-1-deficient mice are resistant to zymosan-induced arthritis: A mini review
... (a-f). Articular cartilage of the wild-type (WT) mice at days 1, 3, and 7 after zymosan injection (a-c). Articular cartilage of the ox-LDL receptor-1 (LOX-1) knockout (KO) mice at days 1, 3, and 7 after ...
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A living cell quartz crystal microbalance biosensor for continuous monitoring of cytotoxic responses of macrophages to single-walled carbon nanotubes
... with Zymosan A (Figure 3A), in some QCM devices only fresh media was then added as shown (red trace) and the frequency remained stable for the duration of the experiment, until trypsin cell removal was performed ...
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Termination of the Respiratory Burst in Human Neutrophils
... to zymosan under conditions in which the myeloperoxidase system was inactive ...the zymosan-treated cells, but did not prevent the sharp fall in activity seen when zymosan exposure exceeded 10 ...
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Original Article Role of biphasic changes in splenic dendritic cell activity in a mouse model of multiple organ dysfunction syndrome
... In the past, many treatments focusing on the inflammatory mediator “cascade” in sepsis and early MODS failed [3-5, 7-9], which suggests that selecting key targets according to the char- acteristics of immune disorder at ...
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Impaired neonatal macrophage phagocytosis is not explained by overproduction of prostaglandin E2
... the opsonized phagocytic defect in young AMs may also relate to diminished Fcg receptor expres- ...for opsonized phagocytosis by macrophages including: FcRII (CD32), FcRIII (CD16) and ...
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In vitro suppression of serum elastase inhibitory capacity by reactive oxygen species generated by phagocytosing polymorphonuclear leukocytes
... phagocytosing opsonized antigen-antibody complexes, produce dialyzable species of activated oxygen which are capable of partially suppressing the elastase-inhibiting capacity (EIC) of whole human serum or purified ...
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Delayed resolution of acute inflammation during zymosan induced arthritis in leptin deficient mice
... in zymosan A injected joints at early (3 days) and late (14 and 21 days) time points after injection ...in zymosan A injected knees of ob/ob and +/? ...
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Multifunctional serine protease inhibitor coated water soluble gold nanoparticles as a novel targeted approach for the treatment of inflammatory skin diseases
... of zymosan in cell viability after incubation with nanoparticles was evaluated by incubating HaCaT cells with ...of zymosan, showing also that zymosan has no influence on viability results (data not ...
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