optical label-free biosensor
Label-free photonics biosensor transducing nano-biological events
... widespread label-free method in the detection of molecular interactions is either optical or photonic-based ...using optical methods over any other methods (electrical and mechanical) are that ...
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Label-free affinity biosensor arrays : novel technology for molecular diagnostics
... glucose biosensor based on an EC-SPR has been demonstrated in which the simultaneous electrochemical and optical measurements were combined to differentiate between the enzymatic activity of glucose oxidase ...
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Highly sensitive label free in vitro detection of aflatoxin B1 in an aptamer assay using optical planar waveguide operating as a polarization interferometer
... of optical biosensors. Several optical PW biosensor devices developed recently are based on the Mach – Zehnder (MZ) interferometer [11 – 15] and ring resonator [16, 17] principles; both approaches ...
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Label-Free Biosensors Based Onto Monolithically Integrated Onto Silicon Optical Transducers
... integrated optical transducers have demonstrated the analytical performance required for application in different fields ranging from biodiagnostics to environmental monitoring and food ...integrated ...
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Label-free detection of γ-aminobutyric acid based on silicon nanowire biosensor
... There are many causes for triggering neurological dis- order, but one of the major cause of the neurological disorder is due to the imbalance of excitatory neuro- transmitters such as GABA (γ-aminobutyric acid) [8, 9]. ...
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Numerical characterisation of label free optical biosensors
... a biosensor comes from its ability to immobilize receptors while maintaining their natural activity, the bioavailability of the receptors to targets in solution and a low nonspecific adsorption to the solid ...
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Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonance
... The LSPR spectra of the nanobiosensor in each processing step are shown in Figure 3. Before modification, the LSPR λ max of the bare silver nanochip was measured at 592.58 nm (Figure 3A). A representative LSPR λ max of ...
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Laser Optical Sensor, a Label Free On Plate Salmonella enterica Colony Detection Tool
... alternative biosensor-based methods (21–24) have been proposed, including fiber-optic sensors (25), surface plasmon res- onance sensors, impedance sensors (22), magnetoelastic biosen- sors (26), and ...
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Optimal design of label free silicon “lab on a chip” biosensors
... advanced biosensor devices, which would be impossible a few years ...incorporate optical wave guide structures with micro fl uidics at chip level, and therefore exhibit superior functionalities Chinese ...
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Electrochemical Determination of Amsacrine at a ds-DNA Modified Graphene Carbon Paste Electrode and its Application as a Label-free Electrochemical Biosensor
... Among carbon material, a new promising group is graphene, which has been interested greatly. It shows excellent electrical conductivity and optical features and it is lightweight with a great specific surface area ...
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Mycotoxin biosensor based on optical planar waveguide
... sensitive optical biosensors capable of label-free detection of toxins ...of optical PW-based sensor devices lies in the use of Mach–Zahender (MZ) interferometers [10–14] and ring resonators ...
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Label free optical detection of mycotoxins using specific aptamers immobilized on gold nanostructures
... the optical method of total internal reflection ellipsometry (TIRE) allowed for label-free detection of small molecules of aflatoxin in direct assay with specific aptamers immobilized on the surface ...
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A label-free biosensor based on silver nanoparticles array for clinical detection of serum p53 in head and neck squamous cell carcinoma
... The measuring procedure was divided into three steps: 1) collecting the reference light without sensor chip, 2) collecting the background noise to increase the accu- racy, and 3) measuring the transmission from the ...
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Functional imaging for regenerative medicine
... saturable optical linear fluorescence transitions (RESOLFT) nanoscopy has been found especially useful for neurons or fixed cells and can be used in fast processes ...
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A Label-free Electrochemical Biosensor for Acrylamide Based on DNA Immobilized on Graphene Oxide-Modified Glassy Carbon Electrode
... a label-free DNA-based electrochemical biosensor for AA based on the interaction between AA with ...the biosensor was linear to the concentration of AA in the range of ...
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Development of Optical Biosensors Based on Metal Nanostructures for Pollution (Mycotoxins) Detection
... complementary to that of target molecules (Ellington and Szostak,1990); they are assembled from a vast pool of amino acids using the SELEX (systematic evolution of ligands by exponential enrichment) procedure. Aptamers ...
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Label-free imaging of thick tissue at 1550nm using a femtosecond optical parametric generator
... for label-free visualization of, for example, blood vessels and red blood cells [3,4], lipid structures [1,5], cell boundaries and membranes [5,6] and brain tissue ...inherent optical sectioning as ...
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A Label-free Multicolor Optical Surface Tomography (ALMOST) imaging method for nontransparent 3D samples
... of opaque samples including information on color and reflective properties. We call our imaging approach A Label-free Multicolor (multi-wavelength) Optical Surface Tomography (ALMOST) method. It is ...
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Preliminary investigations on an enzyme immobilized optical biosensor for arsenite detection
... the optical biosensor into ...enzyme biosensor were found to be consistent at 592 nm in the presence of different arsenite concentrations (Figure ...of biosensor was observed at wavelength of ...
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Fast, Label-Free Tracking of Single Viruses and Weakly Scattering Nanoparticles in a Nanofluidic Optical Fiber
... First, we show that our method can be used to characterize the size distribution of nanoparticles in small fluid volumes. This is a common challenge in nanotechnology, nanomedicine [27] and clinical diagnostics [28]. Our ...
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