Oral antidiabetic drugs
Association between use of oral-antidiabetic drugs and the risk of aortic aneurysm: a nested case–control analysis
... several oral antidiabetic drugs ...oldest drugs for diabetes treat- ment, was shown to inhibit aortic smooth muscle cell proliferation, and matrix metalloprotein (MMP)-2 expression in ...
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Effects of oral antidiabetic drugs on left ventricular mass in patients with type 2 diabetes mellitus: a network meta-analysis
... Our research is the first report to examine how administering OADs to patients with type 2 diabe- tes impacts LVM using the network meta-analysis method. By indirect comparisons using a network meta-analysis, we can ...
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Real-world outcomes of initiating insulin glargine-based treatment versus premixed analog insulins among US patients with type 2 diabetes failing oral antidiabetic drugs
... only oral antidiabetic drugs or glucagon-like peptide-1 in the baseline period were eligible for inclusion, while patients were excluded if they had used any type of insulin, including a PMX, in the ...
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COMPARISON OF DIFFERENT CLASSES OF ORAL ANTIDIABETIC DRUGS IN COMBINATION WITH METFORMIN ON COGNITIVE FUNCTIONS
... Metformin is the first line drug in the treatment of diabetes and is common in all the groups selected for the study. Since it is the first line drug in the clinical setting, other antidiabetic medicines are ...
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Cost effectiveness analysis of liraglutide versus sitagliptin or exenatide in patients with inadequately controlled Type 2 diabetes on oral antidiabetic drugs in Greece
... In general, the sensitivity analyses indicated that these results were robust under a range of assumptions. In the liraglutide against sitagliptin comparison, the key drivers of cost-effectiveness were HbA1c and weight ...
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Cardiovascular mortality and oral antidiabetic drugs: protocol for a systematic review and network meta-analysis
... In this study, authors included randomised clinical trials (RCTs) that were 24 weeks or longer. No statistically significant difference was reported between CV mortality and any drug class. While these findings are ...
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Half of Three Oral Antidiabetic Drugs as a Regimen for Treatment of Type 2 Diabetes Mellitus Patients in Low-income Populations
... The estimated number of diabetes mellitus (DM) patients in 2015, were over 412 million worldwide. With 1 in every 11 adults currently diagnosed, the ratio is expected to increase to 1 in 10 by 2040 [1]. More than 90% of ...
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Concomitant therapy with pioglitazone and insulin for the treatment of type 2 diabetes
... add oral anti- diabetic agents to insulin monotherapy in patients with type 2 ...had oral antidiabetic drugs added to their insulin therapy were less likely to attain glycemic control than ...
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PubMedCentral-PMC5063148.pdf
... IDegLira (Xultophy ® ) is the first fixed-ratio combination of a basal insulin, insulin degludec (IDeg), and a glucagon-like peptide-1 receptor analogue, liraglutide. IDegLira is adminis- tered as a once-daily injection ...
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Luteolin in the Management of Type 2 Diabetes Mellitus
... modifications, oral antidiabetic drugs and ...of oral antidiabetic drugs produces undesirable side ...antioxidant, antidiabetic, anti-inflammatory and anti-cancer ...as ...
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Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease – cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort
... received oral antidiabetic drugs, but no insulin ...and oral anti- diabetic agents ...of oral antidiabetic drugs, alone or in combination, are presented in Table ...with ...
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EFFECT OF COMPETITIVE BINDING OF HYPOGLYCEMIC AGENTS TO HUMAN SERUM ALBUMIN ON DRUG PHARMACOLOGY
... four oral antidiabetic drugs: gliclazide, glimepiride, glipizide and repaglinide in the presence of four categories of competing drugs; one non-steroidal anti-inflammatory drug (parecoxib ...
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TREATMENT PATTERN AND GLYCEMIC CONTROL OF ORAL HYPOGLYCAEMIC DRUGS AMONG TYPE II DM PATIENTS IN ERITREA
... The present retrospective study aimed to explore the treatment pattern and glycemic control of oral antidiabetic drugs among type 2 diabetes mellitus patients in Asmara, Eritrea. This study was ...
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Translating pharmacogenetics to primary care
... Sulfonylureas (SUs) are part of the mainstay of treatment of type 2 diabetes mellitus (T2DM) with oral antidiabetic drugs. They act by closing the pancreatic β -cell potassium channels, stimulating ...
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Prescription Pattern Study in Type 2 Diabetes Mellitus in Diabetic out Patients in Private Clinics in Kerman, Iran
... of antidiabetic drugs studied, 424 ...years. Oral antidiabetic drugs were prescribed for ...prescribed antidiabetic drug combination in diabetic ...prescribed drugs ...
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PRESCRIBING PATTERN OF ANTIDIABETIC DRUGS IN TYPE 2 DIABETIC PATIENTS
... of antidiabetic drugs such as sulfonylureas and ...different drugs, even within a single class, on the risk of long-term vascular complications has come under ...capacity, oral agents are ...
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Simultaneous quantification of ramipril, glimepiride and metformin in human plasma by ultra-performance liquid chromatography – tandem mass spectrometry
... Ramipril (RAM), glimepiride (GLM) and metformin (MET) are recently formulated together for the treatment of diabetes and cardiovascular disorders. This work introduces a liquid chromatography–tandem mass spectrometric ...
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Oral hypoglycemic drugs: An overview
... Metforminals Oral Antidiabetic Agents acts in an insulin-independent manner to suppress other class of oral antidiabetic agent or with ...
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EFFECT OF ORAL ADMINISTRATION OF VITAMIN A ON BLOOD GLUCOSE LEVEL IN RABBITS AND ITS POSSIBLE INTERACTIONS WITH COMMONLY USED ORAL ANTIDIABETIC AGENTS
... ABSTRACT: In diabetes mellitus antioxidant vitamins are commonly employed to prevent or mitigate the long term complications of the disorder. Diabetic retinopathy, nephropathy, coronary and cerebral vascular ...
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ASSESSMENT OF ANTIDIABETIC POTENTIAL OF CAESALPINIA DIGYNA ROTTLER ROOT EXTRACT IN STREPTOZOTOCIN INDUCED DIABETIC RATS
... CONCLUSION: From this study we can conclusively state that Caesalpinia digyna methanolic extract has shown remarkable effects on blood glucose level and marked improvement on hyperlipidemia due to diabetes. Its specific ...
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