osteosarcoma cell lines
Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy
... coma cell lines 143B and U-2 OS, two of the most widely used osteosarcoma cell lines, of which 143B is the only human osteosarcoma cell line with metastatic be- haviour in ...
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Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation
... on cell lines derived from ...reference cell line, but all five patient-derived OSA cell lines were much less sensitive to MTX ...OSA cell lines were not sensitive to the ...
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COMPARISON OF MORPHOLOGICAL AND CELL ADHESION MOLECULES MODULATION BETWEEN PRIMARY OSTEOSARCOMA CELLS AND OSTEOSARCOMA CELL LINES
... Osteosarcoma (OS) is an aggressive primary malignant bone tumour in children and adolescents [1]. The peak incidence of osteosarcoma is associated with pubertal maturation when the growth emission is at its ...
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Identification of genes associated with methotrexate resistance in methotrexate-resistant osteosarcoma cell lines
... However, the DEGs identified in the present study were not the same with those identified to be associated with MTX resistance by Selga et al. using seven cell lines of different types of cancer [9]. This ...
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Antiproliferative effect of Tualang honey on oral squamous cell carcinoma and osteosarcoma cell lines
... For morphological analysis, OSCC and HOS cell lines were seeded in 60-mm dishes at 5 × 10 5 cells/ml. The cells were treated with 2% and 10% concentration of Tualang honey for 24, 48 and 72 hours. At the ...
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Experimental tumor growth of canine osteosarcoma cell line on chick embryo chorioallantoic membrane (in vivo studies)
... human osteosarcoma cell lines to form vascularized solid tumors on the ...fibrosarcoma cell line (FFS1WAW) ...FFS3 cell lines) [5], feline mammary carcinomas [16] and canine ...
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Antitumor effects of pristimerin on human osteosarcoma cells in vitro and in vivo
... human osteosarcoma cells. Treatment of the human osteosarcoma cell lines, MNNG and 143B, with PM led to a dose-dependent decrease in cell ...human osteosarcoma xenografts ...
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Cancer Stem Cells in Osteosarcoma
... osteoblastic osteosarcoma cell ...HOS cell line treated or not treated with cisplatin were isolated and while cisplatin-induced side population cells formed tumours in vivo the side population ...
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Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma
... the cell cycle and promotes microtubule depolymerization ...some osteosarcoma cell lines and its down-regulation increases sensitivity to taxanes ...in cell lines and xenografts ...
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Original Article MiR-218 suppresses osteosarcoma proliferation by down-regulating BMI1
... Abstract: Osteosarcoma is the most frequent cancer of primary bone tissue and is associated with a high meta- static potential and poor ...underlying osteosarcoma progression are not well ...in ...
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Overexpression of carboxypeptidase X M14 family member 2 predicts an unfavorable prognosis and promotes proliferation and migration of osteosarcoma
... human osteosarcoma were ...in osteosarcoma cell lines and tissues were explored by immunohistochemistry and western blotting ...in osteosarcoma cells was silenced through an RNA ...
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mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts
... drugs. Osteosarcoma cell lines, especially SAOS-2 and U-2-OS are frequently used as model systems, remarkably not only to study osteosarcoma, but all types of in vitro cell biological ...
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MEK inhibition induces apoptosis in osteosarcoma cells with constitutive ERK1/2 phosphorylation
... high-grade osteosarcoma is the most common primary bone cancer with relatively high incidence in young ...two osteosarcoma cell lines, which identified MEK1/2 ...six osteosarcoma ...
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A novel circulating hsa_circ_0081001 act as a potential biomarker for diagnosis and prognosis of osteosarcoma
... chemo-sensitive osteosarcoma cell lines (MG63/DXR vs MG63, KHOS/DXR vs KHOS, U2OS/DXR vs U2OS), and found that hsa_circ_0081001 was significantly up-regulated in the OS cell lines, ...
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Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle
... the osteosarcoma cell lines tested, JQ1 treatment decreased MYC expression in a dose- and time-dependent manner ...murine cell lines (Supplementary ...all cell lines ...
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Original Article Loss of SOX5 protein expression by RNAi in osteosarcoma cells suppresses cell proliferation and invasion
... in osteosarcoma remains to be ...in osteosarcoma tissues compared with bone cyst ...two osteosarcoma cell lines, MG63 and U2OS cells, inhibited cell proliferation, G1/S ...
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FOXC2 augments tumor propagation and metastasis in osteosarcoma
... maintaining osteosarcoma cells in a stem-like state. In osteosarcoma cell lines, we show that anoikis conditions stimulate FOXC2 ...In osteosarcoma cell lines, we ...
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Original Article FoxC1 promotes osteosarcoma cell proliferation and metastasis through the activation of EZH2
... of osteosarcoma proliferation, migration and invasion remains to be eluci- ...of osteosarcoma cell proliferation and metastasis and to assess its role as potential therapeutic ...both ...
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Original Article MiRNA-15a inhibits proliferation, migration and invasion by targeting TNFAIP1 in human osteosarcoma cells
... processes. Osteosarcoma is the most common type of primary malignant bone tumor and is characterized by complex genetic changes and resistance to conventional ...of osteosarcoma was ...in ...
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Expression of the immune regulation antigen CD70 in osteosarcoma
... Established osteosarcoma cell lines HOS, HOS-143b, OHS, OSA (SJSA-1), SAOS-2, U2-OS, ZK-58; and Ewing sarcoma cell lines A673, CADO-ES, ET10, EW3, IOR/BER, RD-ES, SK-ES-1, SK-N-MC, ...
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