osteosarcoma tissue
mRNA and protein expression of autophagy marker molecule Beclin1 in osteosarcoma tissue and their correlation with pathological features
... in osteosarcoma, and some studies show that it can both promote and inhibit tumor ...of osteosarcoma, Beclin1 mRNA and protein expression in osteosarcoma tissue and adjacent tissue were ...
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Original Article Expression and function of TAK1 in osteosarcoma tissue
... Our results demonstrate that TAK1 expression is significantly higher in OS tissue and is associ- ated with prognosis in OS patients. Thus, using in vitro cell culture experiments, we treated an OS cell line with a ...
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ING4 expression and clinical parameters of osteosarcoma patients. Besides, the overall survival of osteosarcoma
... 89 osteosarcoma tissues and adjoining normal tissue samples were obtained from patients who were diagnosed as osteosarcoma in The First Affiliated Hospital of Chongqing Medical University from 2005 ...
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Establishment of a patient derived orthotopic osteosarcoma mouse model
... human osteosarcoma tissue directly into the tibia of immunodefi- cient mice resulting in a reproducible and genetically repre- sentative patient xenograft ...using osteosarcoma tissue of three ...
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Original Article HES1 is a positive prognostic factor and inhibits osteosarcoma tumorigenesis
... in osteosarcoma patients and correlated its expression with the OS and RFS of osteosarcoma ...human osteosarcoma tissue with non-tumor adjacent tissue by realtime ...in ...
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<p>LncRNA TDRG1 Promotes Proliferation, Invasion and Epithelial-Mesenchymal Transformation of Osteosarcoma Through PI3K/AKT Signal Pathway</p>
... of osteosarcoma cells through PI3K/AKT signaling ...of osteosarcoma tissues and adjacent tissues were collected, and osteosarcoma cells and osteoblasts were ...in osteosarcoma tissues and ...
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RETRACTED ARTICLE: Down-regulation of microRNA-26a and up-regulation of microRNA-27a contributes to aggressive progression of human osteosarcoma
... We obtained 53 patients with osteosarcomas from Mashhad Hospitals between April 2008 and September 2014. None of the patients enrolled in this study had re- ceived and chemotherapy or radiotherapy before surgery. ...
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Potential role of <em>S</em>-adenosylmethionine in osteosarcoma development
... the osteosarcoma-regulating proteins in different ...bone tissue, pri- mary and metastatic osteosarcoma tissues, and SAM-treated tissues were subjected to Western blotting analysis using anti-Sox2 ...
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Aberrant ADAM10 expression correlates with osteosarcoma progression
... (particularly osteosarcoma) remains un- ...in osteosarcoma tumor cells in a condensed and polarized ...as osteosarcoma progresses, as well as in osteoblastic osteosarcoma tissue, ...
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Tissue microRNA-126 expression level predicts outcome in human osteosarcoma
... For tissue sample collection, 100 pairs of osteosarcoma tissues and corresponding noncancerous bone tissues were col- lected from the same ...100 tissue pairs were collected for each ...All ...
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ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p
... the osteosarcoma cell functions and underlying molecular mechanisms is important for formulating new thera- peutic ...the osteosarcoma cells and found that ADAM10 promoted osteosarcoma cell ...
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Diagnostic Utility of Various Techniques in Bone Tumours.
... Hajdu and Melamed (1984) have emphasized the basic limitation of the technique. The histological architecture is lost in aspiration samples. The drawback was overcome by processing the blood clot separately. This was ...
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Original Article SKA1 promotes the proliferation of osteosarcoma cell through AKT activation and regulates the expression of cyclins
... chamber inserts assays. As shown in Figures 2D and 3C, TRIM59-short hairpin RNA (shRNA) transfection hindered U2OS and Saos-2 cells invasion, which could be recovered by AKT acti- vator; whereas forced expression of Ska1 ...
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Original Article Rosette-forming epithelioid osteosarcoma in childhood: a case report
... by osteosarcoma with rosettes or by conventional osteoblastic osteo- sarcoma ...a tissue- specific transcription factor that plays a critical role in the normal development of embryonic epithelial cells of ...
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Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3A
... human osteosarcoma cells MG-63 and Saos-2 and the highly metastatic MNNG/HOS and KHOS cells to exogenous Sema3A (300 ng/ml) had no efect on their viability ater 48 hours (Supplementary Figure ...human ...
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<p><em>Ilex hainanensis Merr</em> targets ITGAV to suppress the proliferation and metastasis of osteosarcoma cells</p>
... Figure 4 IME enhances the inhibitory effect of DDP on osteosarcoma cells. (A) MG63 and U2OS cells were treated with control, 5 μmol/L DDP, 25 μmol/L IME, or 5 μmol/L DDP combined with 25 μmol/L IME. MTT assay was ...
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<p>Up-Regulation of Hsa_circ_0008792 Inhibits Osteosarcoma Cell Invasion and Migration and Promotes Apoptosis by Regulating Hsa-miR-711/ZFP1</p>
... sponge effect, post-transcriptional regulation, rolling circle translation, circular RNA-derived pseudogenes, and spli- cing interference — and also varies by location, binding site, and acting mode. 8 In recent years, ...
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FBJ osteosarcoma virus in tissue culture. III. Isolation and characterization of non-virus-producing FBJ-transformed cells.
... The parental cell line, when cocultivated with NIH-Swiss-ME cells chronically infected with the cloned FBJ-MuLV, yielded a virus preparation that titrated 1028 FFU/ml in NRK cells and 10[r] ...
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<p>Water Extract of Sporoderm-Broken Spores of <em>Ganoderma lucidum</em> Induces Osteosarcoma Apoptosis and Restricts Autophagic Flux</p>
... In recent years, more studies of traditional Chinese medi- cines about their application in the prevention and treatment of cancer have emerged. 26 One of the most widely used tradi- tional Chinese medicines is G. ...
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Patients with osteosarcoma and soft tissue sarcoma might become "cancer refugees" in some Japanese regional cities
... Purpose: “Rare cancer” is defined as malignancy with a disease prevalence (age-adjusted inci- dence rate) of less than six per 100,000 population. Proper treatments which these patients need cannot always be performed ...
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