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Oxidative phosphorylation (OXPHOS)

Each-step activation of oxidative phosphorylation is necessary to explain muscle metabolic kinetic responses to exercise and recovery in humans

Each-step activation of oxidative phosphorylation is necessary to explain muscle metabolic kinetic responses to exercise and recovery in humans

... 22 23 Key points  during work transitions in human skeletal muscle are still a matter of debate 24 25 The basic control mechanisms of oxidative phosphorylation OXPHOS and glycolysis  W[r] ...

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Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation

Nutrient sensing by the mitochondrial transcription machinery dictates oxidative phosphorylation

... on oxidative phosphorylation (OXPHOS), but precisely how OXPHOS meets the challenge of increased substrate oxidation in fasted liver remains ...and OXPHOS in ...and OXPHOS by the ...

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Sulphide oxidation and oxidative phosphorylation in the mitochondria of the lugworm

Sulphide oxidation and oxidative phosphorylation in the mitochondria of the lugworm

... 1986) and the killifish F. parvipinnis (0.99–1.25; Bagarinao and Vetter, 1990). According to O’Brien and Vetter (1990) the potential for ATP production would be 2.0–4.3 ATP per sulphide, assuming that sulphide oxidation ...

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Mitochondria to motion: optimizing oxidative phosphorylation to improve exercise performance

Mitochondria to motion: optimizing oxidative phosphorylation to improve exercise performance

... in oxidative phosphorylation, which transduce substrates into fuel, are not fixed but remarkably ...of oxidative phosphorylation raises the efficiency of ATP production, while elevating flux ...

7

Limits to sustainable muscle performance: interaction between glycolysis and oxidative phosphorylation

Limits to sustainable muscle performance: interaction between glycolysis and oxidative phosphorylation

... This paper proposes a mechanism responsible for setting the sustainable level of muscle performance. Our contentions are that the sustainable work rate is determined (i) at the muscle level, (ii) by the ability to ...

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Studies in oxidative phosphorylation

Studies in oxidative phosphorylation

... Trialkyl tin compounds have been shown to be potent inhibitors of oxidative phosphorylation, oligomycin sensitive ATPase activity and other ATP-dependent reactions of beef heart mitochon[r] ...

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Discovery of causal mechanisms: Oxidative phosphorylation and the Calvin-Benson cycle

Discovery of causal mechanisms: Oxidative phosphorylation and the Calvin-Benson cycle

... detail: oxidative phosphorylation (the major mechanism of ATP synthesis in mitochondria) and the Calvin-Benson cycle (the light-independent reaction of photo- ...synthesis). Oxidative ...

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Foxp3 drives oxidative phosphorylation and protection from lipotoxicity

Foxp3 drives oxidative phosphorylation and protection from lipotoxicity

... 30%–50% of the cells in an iTreg in vitro induction culture. We compared Foxp3-mediated changes in these cells with those observed in cFoxp3-expressing EL4 cells treated or not with 4’HT. In this way, we aimed to ...

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Relationships between expression of BCS1L, mitochondrial bioenergetics, and fatigue among patients with prostate cancer

<p>Relationships between expression of BCS1L, mitochondrial bioenergetics, and fatigue among patients with prostate cancer</p>

... Mitochondrial oxidative phosphorylation, electron-transport chain enzymatic activity, and BCS1L gene expression were determined using patients ’ peripheral mononuclear ...decreased OXPHOS-complex III ...

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Cycling Exercise Training Enhances Mitochondrial Bioenergetics of Platelets in Patients with Peripheral Arterial Disease: A Randomized Controlled Trial

Cycling Exercise Training Enhances Mitochondrial Bioenergetics of Platelets in Patients with Peripheral Arterial Disease: A Randomized Controlled Trial

... mitochondrial oxidative phosphorylation (OXPHOS) and electron transport system (ETS) in platelets, respectively ...mitochondrial OXPHOS and ETS activities of platelets in PAD ...

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Targeting energy metabolism to eliminate cancer cells

Targeting energy metabolism to eliminate cancer cells

... on oxidative phosphorylation (OXPHOS) to produce energy for cellular processes, cancer cells in the hypoxic microenvironment rely on glycolysis as their primary energy ...

11

Methyl quinones in oxidative phosphorylation

Methyl quinones in oxidative phosphorylation

... Formation of the quinone methide, XXXIV, from the quinone is followed by a nucleophilic 1, 4-addition reaction of the secondary amine with the quinone methide, XXXIV, to form the monosub[r] ...

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: OXIDATIVE PHOSPHORYLATION ABILITY OF MITOCHONDRIA

: OXIDATIVE PHOSPHORYLATION ABILITY OF MITOCHONDRIA

... as Pi esterified, measured by colorimetric and isotopic methods showed no difference in values between control and treated plant mitochondria ATP ase and SDH activities wer[r] ...

7

Differential Requirements For Mitochondria During Neuronal Migration

Differential Requirements For Mitochondria During Neuronal Migration

... mitochondrial oxidative phosphorylation is essential for interneuron ...mitochondrial OXPHOS resulted in decreased migration rates, increasing direction changes and abnormal centrosome ...

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Akt and STAT5 mediate naïve human CD4+ T cell early metabolic response to TCR stimulation

Akt and STAT5 mediate naïve human CD4+ T cell early metabolic response to TCR stimulation

... Metabolic pathways that regulate T-cell function show promise as therapeutic targets in diverse diseases. Here, we show that at rest cultured human effector memory and central memory CD4+ T-cells have elevated levels of ...

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Mitochondrial disorders and the eye

Mitochondrial disorders and the eye

... Despite some clinical similarities, the pattern of retinal ganglion cell loss is considerably different in glaucoma to that seen in LHON and ADOA. In the latter diseases, the small fibers of the papillomacular bundle are ...

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Iron deficiency in the rat  Physiological and biochemical studies of muscle dysfunction

Iron deficiency in the rat Physiological and biochemical studies of muscle dysfunction

... of oxidative phosphorylation with pyruvate-malate, succinate, and alpha-glycerophosphate as substrates were all reduced in mitochondrial preparations from skeletal muscle of iron-deficient rats, but only ...

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An Experimental Assessment Of The Influence Of Ganoderma Lucidum On The State Of Oxidative Stress

An Experimental Assessment Of The Influence Of Ganoderma Lucidum On The State Of Oxidative Stress

... After treatment with Ganoderma Lucidum, it is seen that there is an increase in the activity of the entire respiratory chain (cytochrome c, a, oxidative phosphorylation and conjugacy of oxidative ...

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Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

... of oxidative phosphorylation by addition of ADP, there was a marked lag in initiation of Glc phosphorylation by the mitochondrially bound hexokinase ...by oxidative phosphorylation and ...

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U4-Lecture3IntroCellularRespiration.ppt

U4-Lecture3IntroCellularRespiration.ppt

... LE 9-6_3 Mitochondrion Glycolysis Pyruvate Glucose Cytosol ATP Substrate-level phosphorylation ATP Substrate-level phosphorylation Citric acid cycle ATP Oxidative phosphorylation Oxidati[r] ...

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