p-JNK
<p>Inhibition Of JNK Phosphorylation By Curcumin Analog C66 Protects LPS-Induced Acute Lung Injury</p>
... Figure 6 C66 and SP600125 inhibited LPS-induced inflammation via JNK pathway in macrophages. MPMs were pretreated with C66 at various doses (5, 10 μM) or SP600125 at 10 μ M or vehicle (DMSO) for 30 mins before 0.5 ...
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Proper closure of the optic fissure requires ephrin A5 EphB2 JNK signaling
... of JNK and is pro-apoptotic and ...the p-JNK and p-cJun bands was normalized to total JNK protein, whereas the cleaved caspase 3 band was normalized to an internal actin control: ...the ...
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Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE−/− mice
... phospho-(p)-p38, p-JNK, nuclear NF κ B p65, and phospho-p65 were measured by Western ...of p-p38, p-JNK, nuclear NF κ B p65 and phospho-p65 induced by oxLDL in ...
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Original Article miR-133b in predicting prognosis for patients with osteosarcoma, and its effect on apoptosis of osteosarcoma cells
... of p-p38, p-ERK and p-JNK were detected by Western ...and p-p38, p-ERK, p-JNK was analyzed by Pearson ...of p-p38, p-ERK and p-JNK in ...
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Euphorbia Helioscopia Inhibits The LPS-Induced Pro-Inflammatory Response in RAW 264.7 Cells Via The NF-Κb and MAPK Pathway
... LPS-induced p-JNK and p-ERK kinase expression in ...of p-JNK and p-ERK while the expression of non-phosphorylated JNK and ERK was unaffected by both LPS or LPS plus ...
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Honors Thesis paper CDR upload.pdf
... with JNK-N-8 by intraperitoneal injection twice weekly for one ...of JNK-IN-8 had increased expression of p-JNK, and decreased expression of p-c-Jun and total c-Jun relative to their ...
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<p>Methyloleanolate Induces Apoptotic And Autophagic Cell Death Via Reactive Oxygen Species Generation And c-Jun N-terminal Kinase Phosphorylation</p>
... Figure 6 Reactive oxygen species (ROS) mediate cytotoxicity and cell death induced by methyloleanolate (MO) in H1299 cells. (A) Effect of MO on ROS production in H1299 cells. ROS level was measured as DCFDA by flow ...
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Original Article Suppression of the CXCL4-JNK pathways contributes to the attenuation of DSS-induced acute colitis in mice
... Abstract: Inflammatory bowel diseases (IBD) are chronic disorders of the gastrointestinal tract with a complex ae- tiology. Recently, the incidence of the disease has been on the rise and has received additional ...
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The impact of neuronal Notch-1/JNK pathway on intracerebral hemorrhage-induced neuronal injury of rat model
... Notch-1, p-JNK and active caspase-3 began to increase in the hematoma-surrounding tissues after post-treatment 6 hour following ICH and was peaked at 48 ...
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Norartocarpetin from a folk medicine Artocarpus communis plays a melanogenesis inhibitor without cytotoxicity in B16F10 cell and skin irritation in mice
... h: p-CREB, MITF, TYR, TRP1, TRP-2, p-ERK, p-p38, p-JNK, or GAPDH, and then incu- bated with anti-mouse or anti-rabbit horseradish peroxidase antibody for 1 ...
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Original Article BoNT-A attenuated pain of endometriosis by inhibiting microglia activation
... and JNK in microglia and spinal cord were mea- ...and JNK while down-regulated the protein level of P2X7, CX3R1, p-P38MAPK and p-JNK and up-regulat- ed p-AKT expression compared ...
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Original Article The effect of electrostimulation on apoptosis of spermatogenic cells of testes of the rats after spinal cord injury
... Fas, p-ERK, p-JNK and p-p38 MAPK were detected by immunohistochemistry meth- ...Fas, p-ERK, p- JNK and p-p38 MAPK on 2 weeks group, 4 weeks group and 6 weeks group ...
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Original Article Impact of fluoride on ameloblasts and MAPKs and caspase-12 activity in the tooth germ of rat offspring
... p38 expression increased with the fluoride concentration, which was in agreement with previous reports [6-8]. NaF treatment was found to down-regulate p-JNK expression, whi- ch was involved in the ...
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Reduced beta2-glycoprotein I protects macrophages from ox-LDL-induced foam cell formation and cell apoptosis
... The reaction was terminated by adding 1 mL of cold PBS, which contained 100 μM sodium vanadate. The samples were then placed on ice, washed with ice-cold PBS, and lysed in RIPA lysis buffer for 30 mins. Lysates were ...
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<p>MEX3C regulates lipid metabolism to promote bladder tumorigenesis through JNK pathway</p>
... Western blotting analyses were performed using standard protocols. The protein samples were resolved by SDS- PAGE and transferred onto Polyvinylidene Fluoride (PVDF) membranes (Basel, Switzerland, Roche). The mem- branes ...
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The expression of p ATF2 involved in the chondeocytes apoptosis of an endemic osteoarthritis, Kashin Beck disease
... adjust an equivalent loading dose of 50 μg. Before electro- phoresis, all the samples were boiled in sodium dodecy- lsulfate (SDS) sample buffer for 5 mins. The lysates were separated by polyacrylamide gel ...
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Original Article Activation of c-Jun/JNK signaling predicts poor prognosis in nasopharyngeal carcinoma
... Phospho-Thr183/185 JNK (p-JNK) (1:50, product’s ID: ab131499) with monoclonal antibody (Abcam, Cambridge, UK) were added for incubation at 37°C for 1 ...
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<p>URM1 Promoted Tumor Growth and Suppressed Apoptosis via the JNK Signaling Pathway in Hepatocellular Carcinoma</p>
... anti p-P53 (1:1000;CST; #2528), anti-Bax (1:5000; Proteintech; 500599-2-lg), anti-JNK1/2 (1:1000; CST; 9592), anti p-JNK (1:1000; CST; 9251S), anti-TP53 (1:500; CST; #2527), and anti-GAPDH (Santa ...
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MAPK/FoxA2-mediated cigarette smoke-induced squamous metaplasia of bronchial epithelial cells
... the JNK inhibitor SP600125, or the p38 inhibitor ...harvested. p-ERK, p-p38 and p-JNK protein levels in cells and lung tissue were measured using enzyme- linked immunosorbent assays, ...
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Role of JNK and ERK1/2 MAPK signaling pathway in testicular injury of rats induced by di-N-butyl-phthalate (DBP)
... quality assessment can reflect the ultimate toxic effects of environmental factors on male reproductive damage. We found that DBP can reduce the sperm count and viability of male animals, increased sperm deformity rate, ...
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