Paraxial mesoderm
Zygotic VegT is required for Xenopus paraxial mesoderm formation and is regulated by Nodal signaling and Eomesodermin
... of paraxial protocadherin (PAPC), encoding a cell adhesion molecule, during gastrulation (Yamamoto et ...trunk paraxial meso- derm of Spadetail mutant embryos is highly deficient and tail development is ...
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Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro
... large amounts of muscle cells in vitro and in vivo. Here, we describe a robust, serum-containing protocol based on Wnt signaling activation and BMP inhibition to efficiently produce PSM-like cells from mouse ESCs and ...
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FGF and canonical Wnt signaling cooperate to induce paraxial mesoderm from tailbud neuromesodermal progenitors through regulation of a two step epithelial to mesenchymal transition
... first mesoderm-inducing signal discovered was the fibroblast growth factor (FGF) pathway (Dorey and Amaya, 2010; Kiecker et ...induce mesoderm in naïve epiblast cells (Kimelman et ...stage paraxial ...
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Fgf8a induces neural crest indirectly through the activation of Wnt8 in the paraxial mesoderm
... dorsolateral mesoderm, ...involuting mesoderm, the future paraxial mesoderm, while Fgf8 remains confined to the posterior ...the mesoderm expression of Wnt8 underlying the first ...
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In Vitro Generation of Neuromesodermal Progenitors Reveals Distinct Roles for Wnt Signalling in the Specification of Spinal Cord and Paraxial Mesoderm Identity
... in mesoderm and neural induction ...and paraxial mesoderm proceeds by Wnt and Fgf signalling inducing a neuromesodermal bipotential ...and paraxial mesoderm from mouse and human ...
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Xtbx6r, a novel T box gene expressed in the paraxial mesoderm, has anterior neural inducing activity
... the paraxial mesoderm in the caudal region in a very similar manner to Xtbx6, with a slight difference in that the former is emphasized more dorsally and has a more restricted distribution along the ...
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Inhibition of the cell cycle is required for convergent extension of the paraxial mesoderm during Xenopus neurulation
... the paraxial and axial mesoderm, respectively (Dosch et ...the paraxial mesoderm by stage 18 of development (compare panels 1 and ...of paraxial mesoderm cells, particularly in ...
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BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites
... plate mesoderm To further explore how mutant somites were patterned, the expression for several markers for PXM development was ...presomitic mesoderm) was expressed as a column on each side of the embryo ...
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Regulation of cranial morphogenesis and cell fate at the neural crest mesoderm boundary by engrailed 1
... cephalic paraxial mesoderm (Mes) cells, which migrate rapidly to a supraorbital domain and establish a unidirectional lineage boundary with neural crest (NeuC) ...
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Normal and aberrant craniofacial myogenesis by grafted trunk somitic and segmental plate mesoderm
... trunk mesoderm cells that occupy these exact sites will aggregate and express muscle-specific transcription factors and MyHC on the normal head ...nearby paraxial mesoderm cells taken from any part ...
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The road to the vertebral formula
... anterior paraxial mesoderm, expression of the Cdx gene family is mostly localized to posterior embryonic areas (Meyer and Gruss, 1993; Gamer and Wright, 1993; Beck et ...the mesoderm and neurectoderm ...
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Making muscle: skeletal myogenesis in vivo and in vitro
... of mesoderm, both along the anterior-posterior axis at the early primitive streak stage and later along the mediolateral axis during late primitive streak and tail bud stages (Winnier et ...extraembryonic ...
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Genomic integration of Wnt/β catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs
... Since some digestive organs, including the esophagus, stomach, intestine and pancreas originate from both ventral and dorsal endoderm cells (Chalmers and Slack, 2000), we hypothesized that ventral and dorsal transcripts ...
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Coupling segmentation to axis formation
... Three main events take place in the rostral primitive streak and tailbud, which lead to the generation of the PSM: proliferation, specification and emigration. The multiple factors that play a role in each of these steps ...
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Tbx6, Mesp b and Ripply1 regulate the onset of skeletal myogenesis in zebrafish
... lateral paraxial mesoderm, indicating that Tbx6 and/or Tbx6-dependent genes inhibit maturation of myogenic ...lateral paraxial mesoderm ...anterior paraxial mesoderm where ...
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Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice
... mouse paraxial mesoderm (Forlani et ...and mesoderm tissues, and the more anterior Hox boundaries in neural tissue may then be explained by the more anterior boundaries of Cdx proteins in neural ...
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Determination, diversification and multipotency of mammalian myogenic cells
... of paraxial mesoderm, axial structures (neural tube/notochord complex) are required to promote ...the paraxial mesoderm, do not need the neural tube/notochord complex but rather require a ...
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Cdx2 regulation of posterior development through non Hox targets
... nascent mesoderm with an anterior limit in the posterior hindbrain (Meyer and Gruss, ...the paraxial mesoderm, with a rostral limit posterior to the most recently formed ...the paraxial ...
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Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm
... cranial paraxial mesoderm and the ALPM is consistent with a previous report showing that cyp26c1 is expressed medial to the ALPM (marked by ...head mesoderm for a limited time window at early ...
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Co expression of Tbx6 and Sox2 identifies a novel transient neuromesoderm progenitor cell state
... 2009). The feedback loop involving Wnt/ β -catenin signaling and its target T is speculated to be key for maintenance of the NMP pool (Martin and Kimelman, 2012). By contrast, another T-box factor, Tbx6, a downstream ...
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