PECAM-1
The biology of PECAM 1
... that PECAM-1 is a key par- ticipant in the adhesion cascade leading to extravasation of leukocytes during the inflammatory ...for PECAM-1 inhibited their em- igration across an endothelial ...
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Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM 1–deficient mice
... in PECAM-KO ...in PECAM-KO monolayers. Endothe- lioma cells derived from the lungs of PECAM-KO mice or the same cells reconstituted with PECAM-1 (PECAM-RC) were cultured to ...
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Decrease of PECAM-1-gene-expression induced by proinflammatory cytokines IFN-γ and IFN-α is reversed by TGF-β in sinusoidal endothelial cells and hepatic mononuclear phagocytes
... of PECAM-1 in rat livers after the administration of CCl 4 , in this study we aimed to identify cytokines that were responsible for the down-regulation of PECAM-1 on SECs and on transmigrating ...
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A novel role for PECAM-1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow
... that PECAM-1 is involved in the migration of bone marrow progenitors from the blood to the bone ...when PECAM-1 is deleted from either the endothelium or adoptively transferred ...the ...
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Platelet Endothelial Cell Adhesion Molecule (PECAM 1) Expression in Malignant Human Tumours and their Metastases
... Although PECAM-1 expression has been studied in cel- lular lines of solid tumours, leukemias and lymphomas to the best of our knowledge the expression of this adhesion protein has not been evaluated in ...
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Huff, Ines (2008): Effekte des vaskulären Immunotargeting mit anti-PECAM-1/NA/Katalase Konjugaten auf die Lungenfunktion nach experimenteller Transplantation von Lungen nicht herzschlagender Spender im Großtiermodell. Dissertation, LMU München: Medizinische Fakultät
... anti-PECAM- 1/NA/Katalase Konjugate in vitro spezifisch an Endothelzellen binden und die durch reaktive Sauerstoffspezies induzierte endotheliale Dysfunktion verhindern ...
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Evaluation of PECAM-1 and p38 MAPK expressions in cerebellum tissue of rats treated with caffeic acid phenethyl ester: a biochemical and immunohistochemical study
... Caffeic acid phenethyl ester has been reported to block many inflammatory agents (primarily tu- mour necrosis factor alpha) by blocking nuclear factor kappa B (NF-kB) and oxygen radicals. It has also been shown that CAPE ...
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Lamparter, Mathias (2008): Foxc1 regulates Pecam-1 Expression in embryonic Endothelial Progenitor Cells. Dissertation, LMU München: Fakultät für Biologie
... where Pecam-1 expression is regulated during the maturation and differentiation to macrophages ...During PECAM-1 activation in human myeloid cells, specific transcription factors, ...initiate ...
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Original Article Hydrogen sulfide exerts antithrombotic effects and inhibits deep vein thrombosis through NOS-PECAM-1 signaling pathway
... and PECAM-1 ...inhibit PECAM-1 expression in HUVECs cells to explore the role of PECAM-1 in the anti-thrombotic ...of PECAM-1, eNOS and iNOS in DVT mice. Inhibition ...
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A preliminary study of pamidronic acid downregulation of angiogenic factors IGF-1/PECAM-1 expression in circulating level in bone metastatic breast cancer patients
... and PECAM-1 concentrations, and the prognosis of patients in IGF-1 unmodified group was relatively poor; moreover, previous hormonotherapy may improve patients’ responses to BP therapy in ...
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Genetic variation in the PECAM-1 gene and its role in atherosclerosis and coronary heart disease
... immunoprecipitated PECAM-1, however this was not possible due to technical difficulties in immunoprecipitating ...stimulation, PECAM-1 tyrosine phosphorylation in quiescent HUVECs of the RR ...
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Engagement of human PECAM 1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release
... particular PECAM-1, activate or interact with tyrosine ki- nases remains an area of ongoing ...that PECAM-1 itself is ...of PECAM-1 has no intrinsic kinase activity and is not ...
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Switched at birth: a new family for PECAM 1
... (PECAM- 1, or CD31) is a 130-kDa member of the immunoglob- ulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell ...pattern, ...
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Asn563Ser polymorphism of <em>CD31/PECAM-1</em> is associated with atherosclerotic cerebral infarction in a southern Han population
... Results: In this study, statistically significant differences in Asn563Ser genotype and allele dis- tribution were found between the cases and controls (P0.05). Furthermore, logistic regression analysis showed that the ...
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5498.pdf
... In PECAM-1-expressing ECs, eNOS distributed primarily into two distinct pools: light membranes highly enriched in caveolin-1 and heavy membranes enriched in ...
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Circulating concentration of markers of angiogenic activity in patients with sarcoidosis and idiopathic pulmonary fibrosis
... PDGF-BB, PECAM-1 and VEGF were measured in duplicate (the mean value from 2 measurements was de- rived) using commercially available multiplex bead- based sandwich immunoassay kits (Human Angiogenesis ...
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Sex differences in the expression of cell adhesion molecules on microvesicles derived from cultured human brain microvascular endothelial cells treated with inflammatory and thrombotic stimuli
... MV derived from untreated female cells were isolated as described above and quantified by FACS for total PECAM-1/annexin V-positive vesicles, then labeled with PKH67, a green fluorescent cell membrane ...
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Interplay between Platelet Endothelial Cell Adhesion Molecule 1 and Pigment Epithelium Derived Factor in Non Small Cell Lung Cancer
... by PECAM-1 (Plate- let Endothelial Cell Adhesion Molecule-1) ...staining. PECAM-1 is a 130-kDa integral membrane protein, also known as CD31, a cell adhesion molecule with proangiogenic ...
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Kaposi Sarcoma: Clinical Indices and Diagnosis
... plaques and nodules. Immunohistochemistry of Kaposi sarcoma has been evaluated with more than one hundred (100) million antibodies. Cells from KS lesions stain positively with endothelial markers like CD31 ...
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The role of microparticles in chronic obstructive pulmonary disease
... junctions. PeCAM-1 and MCAM are located outside of adherence ...cells; PeCAM, platelet endothelial cell adhesion molecule; MCAM, melanoma cell adhesion molecule; ve, vascular endothelial; MPs, ...
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