pH-Responsive
Control of targeting ligand display by pH responsive polymers on gold nanoparticles mediates selective entry into cancer cells
... show pH-triggered receptor-mediated endocytosis of nanoparticles via surface ligand ...a pH-responsive and a hydrophilic block. At the normal serum pH of ...the pH-responsive ...
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PH-Responsive Schizophrenic Diblock Copolymers Prepared by Polymerization-Induced Self-Assembly
... a pH of ...solution pH to pH 10, nanoparticle inversion occurs and the MAA residues become ...dual pH- responsive sterically stabilized nanoparticles have been characterized using 1 H ...
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pH-responsive polymer microcapsules for targeted delivery of biomaterials to the midgut of Drosophila suzukii
... gut pH for ...in pH was exploited for a triggered release of cargo from the pH-responsive microcapsules at the main site of nutrient uptake by the insect ...the pH-responsive ...
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Polyaspartic acid-anchored mesoporous silica nanoparticles for pH-responsive doxorubicin release
... Herein, we have designed doxorubicin-loaded polyaspartic acid-anchored MCM-41-type mesoporous silica nanoparticles (symbolized as DOX@P-MSNs) that demonstrate pH- responsive in vitro and intracellular drug ...
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Stepwise pH-responsive nanoparticles for enhanced cellular uptake and on-demand intracellular release of doxorubicin
... stepwise pH-responsive nanodrug deliv- ery system was developed to efficiently deliver and significantly promote the therapeutic effect of doxorubicin ...first-step pH response, wherein surface ...
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Blood TfR+ exosomes separated by a pH-responsive method deliver chemotherapeutics for tumor therapy
... This work was a continuation of our previous research [37], wherein the focus was on the formation of SMNC-EXOs to simultaneously realize the separation, purification, and tumor targeting of exosomes. In contrast, here, ...
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pH-responsive perylenediimide nanoparticles for cancer trimodality imaging and photothermal therapy
... Herein, pH-responsive perylenediimide nanoparticles (PPDI-NPs) were developed for NIRF/PA/infrared thermal (IRT) trimodality imaging and PTT (Scheme ...
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Thermo and pH Responsive Hydrogels Based on N Isopropylacrylamide and Allylamine Copolymers
... and pH-responsive hy- drogels were synthesized via copolymerization of N- isopropylacrylamide and allylamine hydrochloride mono- ...and pH of the ...
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pH-responsive hybrid nanoparticle with enhanced dissociation characteristic for siRNA delivery
... formulations were done under acidic pH. As shown in Figure 2D, ζ -potential of LR was found to be + 23.8 mV, while those of both PHD/LR and PD/LR were nearly electri- cally neutral. When the pH was kept as ...
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Dextran-<em>b</em>-poly(<em>L</em>-histidine) copolymer nanoparticles for pH-responsive drug delivery to tumor cells
... poly(L-histidine). pH-responsive nanoparticles incorporating doxorubicin were fabricated and studied in HuCC-T1 cholangiocarcinoma ...with pH sensitivity, ie, the size of the nanoparticles increased ...
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pH-responsive theranostic nanocomposites as synergistically enhancing positive and negative magnetic resonance imaging contrast agents
... Results: Theranostic nanocomposites Mn-porphyrin&Fe 3 O 4 @SiO 2 @PAA-cRGD were fabricated and characterized, and the nanocomposites were effectively used in T 1 - and T 2 -weighted MRI and ...
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pH-responsive high-density lipoprotein-like nanoparticles to release paclitaxel at acidic pH in cancer chemotherapy
... a pH-responsive HDL-like nanoparticle that selectively releases paclitaxel, a model antitumor drug, at acidic ...of pH values ...low pH. The paclitaxel nanoparticle was stable at physiological ...
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Development and evaluation of pH-responsive single-walled carbon nanotube-doxorubicin complexes in cancer cells
... strong pH-responsive drug release, which may facilitate effective DOX release near the acidic tumor microenvironment and thus reduce its overall systemic ...
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Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications
... nm) tend to be rapidly taken up by the mononuclear phagocytic system (MPS) and subsequently accumulate in the liver, spleen, and to a lesser extent in the bone marrow [1, 83-88]. Compared to the tight endothelial ...
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Novel pickering emulsifiers based on pH-responsive poly(2-(diethylamino)ethyl methacrylate) latexes
... the pH-responsive nature of the charge-stabilized PTBAEMA latex in aqueous solution, with a latex-to-microgel swelling transition being observed (see ...to pH-responsive Pickering emulsifier ...
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Multifunctional folate receptor-targeting and pH-responsive nanocarriers loaded with methotrexate for treatment of rheumatoid arthritis
... and pH-responsive FA-PPLNPs/Mtx were developed for the treatment of ...excellent pH-responsiveness with accelerated drug release at acidic ...
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Effects of a novel pH-sensitive liposome with cleavable esterase-catalyzed and pH-responsive double smart mPEG lipid derivative on ABC phenomenon
... able pH-responsive hydrazone and esterase-catalyzed ester linkages so that the PEGylated coating can be efficiently removed by the lower pH and esterase in the ...and pH-responsive ...
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pH-responsive charge-reversal polymer-functionalized boron nitride nanospheres for intracellular doxorubicin delivery
... and pH-responsive controlled release of DOX into cancer ...its pH-responsive and controlled drug-release properties, PAH-cit-functionalized BNNS will be a promising candidate for cancer ...
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Design of a pH-responsive conductive nanocomposite based on MWCNTs stabilized in water by amphiphilic block copolymers
... evident pH-responsive behavior, being MWCNTs reaggregation promoted in basic ...conductivity responsive to pH variations, showing the potential of such materials for sensing ...
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Intracellular delivery of doxorubicin encapsulated in novel pH-responsive chitosan/heparin nanocapsules
... the pH-responsive property of the capsule wall, which is determined by the pKa of the ...the pH is varied, about 64% of the drug is released in acidic pH while 77% is released in neutral ...
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