Phospholipid metabolism
Plasma disturbance of phospholipid metabolism in major depressive disorder by integration of proteomics and metabolomics
... tion analysis instead of investigating the relationship between differential proteins and metabolites at the mathematical level. Second, iTRAQ and label free, as two very popular quantitative proteomic analysis meth- ...
11
Envelope Formation Is Blocked by Mutation of a Sequence Related to the HKD Phospholipid Metabolism Motif in the Vaccinia Virus F13L Protein
... The outer envelope of the extracellular form of vaccinia virus is derived from Golgi membranes that have been modified by the insertion of specific viral proteins, of which the major component is the 37-kDa, ...
10
The medical food Souvenaid affects brain phospholipid metabolism in mild Alzheimer’s disease: results from a randomized controlled trial
... brain phospholipid metabolism in patients with Alzheimer ’ s ...of phospholipid synthesis and breakdown (phosphomonoesters [PME] and phosphodiesters [PDEs]), neural integrity (N-acetyl aspartate), ...
11
Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition
... mediating phospholipid turnover, such as phospholipases A, C and D (catabolic pathway) and choline kinase and choline transport into cells (anabolic pathway) which have all been reported to be altered in ...
13
Myotonic muscular dystrophy: defective phospholipid metabolism in the erythrocyte plasma membrane
... Myotonic muscular dystrophy (MyD) is a systemic genetic disorder that is thought to result from a generalized cellular membrane defect although the exact nature of this defect is unknown. This study examines two ...
6
Effect of fatty acids on growth of Japanese encephalitis virus cultivated in BHK-21 cells and phospholipid metabolism of the infected cells.
... The present investigation is a report on i the effect of exogenous fatty acids on multiplication of JEV in hamster kidney cells BHK-21 cells cultivated in Waymouth medium as a first step[r] ...
11
Phospholipid Metabolism in the Initiation of Renal Compensatory Growth after Acute Reduction of Renal Mass
... The increase in rate of choline incorporation into renal phospholipid was independent of choline uptake. [ 14 C]Choline was found to be a specific precursor of the three renal phospholipids, phosphatidylcholine, ...
8
Phospholipid metabolism in Pseudomonas BAL-31 infected with lipid-containing bacteriophage PM2.
... These data are in contrast to the findings of Tsukagoshi and Franklin 11 and suggest that PM2 infection does not lead to a change in the rate of PE and PG biosynthesis until the onset of[r] ...
11
Phospholipid Metabolism in T4 Bacteriophage-infected Escherichia coli K-12 (λ)
... The uptake of 32Pi into phospholipids of cells infected with T4Bs and endolysin-negative mutants was similar to that observed with the wild-type phage, suggesting that the development of[r] ...
6
Adenovirus E1A proteins stimulate inositol phospholipid metabolism in PC12 cells.
... Phospholipase C activity was increased severalfold in both membrane and cytosol fractions of 12E1APC12 or 5E1APC12 cells, compared with that in parental PC12 cells Table 2.. However, the[r] ...
6
<p>Serum untargeted lipidomic profiling reveals dysfunction of phospholipid metabolism in subclinical coronary artery disease</p>
... Coronary artery calci fi cation (CAC) is a marker for sub- clinical coronary artery disease in patients with intermediate risk and has been shown to improve risk prediction of CAD events. 7 CAC is accurately quanti fi ed ...
13
Phospholipid Metabolism in Stimulated Human Platelets: CHANGES IN PHOSPHATIDYLINOSITOL, PHOSPHATIDIC ACID, AND LYSOPHOSPHOLIPIDS
... phosphorus assay of major and minor components following separation by two-dimensional thin-layer chromatography. This procedure obviated the use of radioactive labels. Extensive changes were found in quantities of ...
10
Concomitant Alterations of Sodium Flux and Membrane Phospholipid Metabolism in Red Blood Cells: Studies in Hereditary Spherocytosis
... Radioactivity of the "acidic phosphatides" phosphatidylserine and phosphatidic acid fractions decreased, in general, when the sodium flux was low, i.e., when the cells were suspended in [r] ...
14
Increased calcium absorption in prehypertensive spontaneously hypertensive rat Role of serum 1,25 dihydroxyvitamin D3 levels and intestinal brush border membrane fluidity
... In view of the recently reported differences in membrane fluidity, structure, phospholipid metabolism 10-13, and membrane Ca handling 14-18 between the SHR and WKy control, and in view o[r] ...
9
A calorimetric study of the formation and stability of phospholipid vesicles
... remove phospholipid molecules from the vesicle bilayer, leading to varying degrees of vesicle disintegration and release of encapsulated solutes at rates dependent on the extent o f bilayer ...
193
Mitochondrial role in the neonatal predisposition to developing nonalcoholic fatty liver disease
... tathione metabolism (114), thereby implicating the major role of altered antioxidant activity in the progression of NAFLD to ...one-carbon metabolism plays in the assembly and retention of hepatic ...
13
The metabonomics study of P-selectin glycoprotein ligand-1 (PSGL-1) deficiency inhibiting the progression of atherosclerosis in LDLR-/- mice
... Atherosclerosis (AS) is a multi-factorial chronic disease commonly associated with the mechanisms of metabolism disorder, endothelial dysfunction and chronic inflammation. AS an inflammatory molecule, p-selectin ...
11
4 Membrane Structure-S
... the phospholipid molecules will spontaneously assemble into a phospholipid bilayer where the layers are held together by weak attractive forces between ...
6
Key Steps in the Early Evolution of Life from the Origin of Protein Synthesis to Modern Cellular Life
... the phospholipid membrane into the plasma membrane; (2) the origin of primitive cytoplasm; (3) primitive gene regulation; (4) the beginnings of the virus world; and (5) the advent of ...
52
Molecular Probes in Tandem Electrospray Ionization Mass Spectrometry: Application to Tracing Chemical Changes of Specific Phospholipid Molecular Species
... oxidized phospholipid species, PC-OOH such as 2 occur in mammalian blood at very low concentrations, and they are believed to be deeply involved in aging, physiological disorders and diseases [16-19] including ...
11