Pima Indians
Significance of Health Related Predictors of Diabetes in Pima Indians Women
... in PIMA women where those without diabetes develop high blood sugar levels during ...in Pima Indians may also be occurring in the same pattern in other ...in Pima Indians population, ...
10
Glomerular function in Pima Indians with noninsulin dependent diabetes mellitus of recent onset
... 20 Pima Indians with noninsulin-dependent diabetes mellitus (NIDDM) of less than 3 yr ...28 Pima Indians with normal glucose tolerance served as ...
8
Polymorphism in the 5' flanking region of the human insulin gene Relationships with noninsulin dependent diabetes mellitus, glucose and insulin concentrations, and diabetes treatment in the Pima Indians
... relationships between insulin and glucose concentrations. 61% (11/18) of the diabetics with a class 3 allele were receiving drug treatment for diabetes compared with only 26% (8/31) of diabetics without a class 3 allele ...
8
Postabsorptive respiratory quotient and insulin stimulated glucose storage rate in nondiabetic pima indians are related To glycogen synthase fractional activity in cultured myoblasts
... A high RQ, indicating a low ratio of lipid to glucose oxida- tion rates, predicts subsequent weight gain in Pima Indians (3) and in nonobese Caucasian men (4). Percent fat has been posi- tively correlated ...
7
Linkage between obesity and a marker near the tumor necrosis factor alpha locus in Pima Indians
... Because tumor necrosis factor-alpha (TNF-alpha) expression is increased in adipose tissue of both rodent models of obesity and obese humans, it has been considered as a candidate gene for obesity. Pima ...
6
Minimal Rule Based Classifiers using PCA on Pima Indians Diabetes Dataset
... Consequently, this research recommends using the PCA as a data reduction technique to achieve its goal of obtaining high accurate minimal classification rules. Among three classifiers namely Support vector machine, ...
7
An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians
... 363 nondiabetic Pima Indians were genotyped at 516 polymorphic microsatellite markers on all 22 autosomes. Linkage analyses were performed using three methods (sin- gle-marker, nonparametric multipoint ...
9
Insulin resistance associated with lower rates of weight gain in Pima Indians
... unknown. We measured glucose disposal rates at submaximally- and maximally-stimulating insulin concentrations in 192 nondiabetic Pima Indians and followed their weight change over 3.5 +/- 1.8 y (mean +/- ...
7
Evidence for reduced thermic effect of insulin and glucose infusions in Pima Indians
... glucose-tolerant Pima Indians, a population with a high prevalence of ...male Indians matched for glucose storage rates and ...the Indians compared with ...
7
Effect of a high carbohydrate, low saturated fat diet on apolipoprotein B and triglyceride metabolism in Pima Indians
... The mechanisms by which high-carbohydrate, low-saturated-fat diets lower LDL cholesterol (LDLC) concentrations are unknown. In this study, kinetics of VLDL, intermediate density lipoprotein (IDL), and LDL apoprotein B ...
10
Relationship between obesity and maximal insulin stimulated glucose uptake in vivo and in vitro in Pima Indians
... Previous studies have left unanswered whether human obesity, independent of glucose intolerance, is associated with a "postreceptor" defect in insulin action. We have studied the relationship between the degree ...
7
Characterization of lipase activities in obese Pima indians Decreases with weight reduction
... Adipose tissue and muscle lipoprotein lipase and postheparin hepatic and lipoprotein lipase activities have been measured in a group of 21 Pima Indian males over a wide range of body weight to determine the ...
8
Perinatal Mortality and Morbidity in Diabetes Mellitus Complicating Pregnancy
... Pettitt DJ, Knowler WC, Baird HR, Bennett PH, Gestational diabetes infant and maternal complications of pregnancy in relation to third trimester glucose tolerance in Pima indians, Diabet[r] ...
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Abnormal regulation of ribosomal protein S6 kinase by insulin in skeletal muscle of insulin resistant humans
... primary lesion responsible for insulin resistance, we investigated the influence of insulin on ribosomal protein S6 kinase activities in skeletal muscle of insulin-sensitive and insulin- resistant nondiabetic Pima ...
6
A Chaotic Levy Flights Bat Algorithm for Diagnosing Diabetes Mellitus
... Bat algorithm is a meta-heuristic algorithm that is based on the echolocation behavior of bats. The searching behavior of the algorithm depends on generating uniformly distributed random walks in the search space. Hence, ...
7
Activation of skeletal muscle casein kinase II by insulin is not diminished in subjects with insulin resistance
... nondiabetic, and five insulin-resistant diabetic Pima Indians during a 2 h hyperinsulinemic, euglycemic clamp. In sensitive subjects, CKII was transiently activated reaching a maximum over basal activity ...
7
Blood pressure measurement at two years in offspring of women randomized to a trial of metformin for GDM: follow up data from the MiG trial
... In a landmark study of pregnancy outcome in Pima Indians, children born to mothers with Type 2 diabetes or gestational diabetes mellitus (GDM) were larger for gestational age at birth an[r] ...
5
A Data Driven Method for Selecting Optimal Models Based on Graphical Visualisation of Differences in Sequentially Fitted ROC Model Parameters
... Based on the ROC convention, a classifier is optimal only if it yields results in the top left corner, given the set conditions. Thus, the performance ranking in both cases was DT-1, DT-2, and DT-3. The maximum ...
8
The Deletion Polymorphism in Exon 8 of Uncoupling Protein 2 is Associated with Severe Obesity in a Saudi Arabian Case-Control Study
... of Pima Indians; however, several association studies have since been conducted to evaluate whether this insertion/deletion polymorphism is associated with obesity, and/or related disorders such as type II ...
5
Indians in the colonial medical service
... academics generally considered not only the shorter ‘subordinate’ training but also the GMC approved courses offered by colleges to be inferior to that available in the West. So much so, that the poorer quality was ...
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