pituitary tumors
Loss of Central Nervous System Component of Dopaminergic Inhibition of Prolactin Secretion in Patients with Prolactin Secreting Pituitary Tumors
... with pituitary tumors were given l-dopa, ...with pituitary tumors and elevated plasma PRL (73±14 ng/ml), l-dopa alone led to PRL suppression comparable with that in normal subjects ...
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Gonadotropin releasing hormone receptor mRNA expression by human pituitary tumors in vitro
... these tumors may be due to GnRH receptor (GnRH-Rc) biosynthetic ...responsive tumors and normal human ...human pituitary tumors. We conclude (a) one third of gonadotroph tumors respond ...
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Refractory pituitary adenoma: a novel classification for pituitary tumors
... Only pituitary tumors with cerebrospinal and/or systemic metastasis are considered malignant ...some pituitary adenomas with high Ki-67 indexes exhibit aggressive behaviors, such as rapid growth, ...
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Headache associated with pituitary tumors
... in pituitary tumors and their char- acteristics, the relationship between pituitary tumor size, biological type, local extension and intrasellar pressure ...primary pituitary masses at ...
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Clinically nonfunctioning pituitary tumors are monoclonal in origin
... of pituitary tumors using X- linked restriction fragment length polymorphisms at the phosphoglycerate kinase and hypoxanthine phosphoribosyl-transferase ...six pituitary adenomas. All six ...
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Potential bias in testing for hyperprolactinemia and pituitary tumors in risperidone-treated patients: a claims-based study
... of pituitary tumor. The frequency of diag- nosed pituitary tumors can also be determined from claims ...itary tumors, the first by expanding the patient base and the second, ...of ...
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Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors
... in pituitary tumors. Initial studies showed patients whose tumors exhibited PD-L1 expression demonstrated improved clinical responses compared to patients with PD- L1 negative tumors when ...
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Somatostatin receptor (SSTR) subtype selective analogues differentially suppress in vitro growth hormone and prolactin in human pituitary adenomas Novel potential therapy for functional pituitary tumors
... GH-cell tumor cultures. Specimens cultured from six patients with GH-secreting adenomas were studied. Somatotroph ade- noma cells obtained from patient 1 (Table II) did not respond to either octreotide or lanreotide (10 ...
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Predictors of Cerebrospinal Fluid Leaks in Endoscopic Surgery for Pituitary Tumors
... This is a retrospective cohort study conducted at our skull base unit, Neurosurgery Department, Mansoura University Hospitals. Institutional Review Board approval was obtained to perform a retrospective review of ...
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Mechanisms for pituitary tumorigenesis: the plastic pituitary
... Generalized pituitary hyperpla- sia would be expected if the adenomatous growth were induced in response to hypothalamic hormone over- ...anterior pituitary cells to regulate anterior pituitary hor- ...
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Functional role of estrogen in pituitary tumor pathogenesis
... modulating pituitary angiogenesis and tumor ...that pituitary pttg is induced by estrogen and bFGF, the latter being expressed in a concordant fashion with pttg in experimental and human pituitary ...
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Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP -positive cells
... these tumors originates from neural precursors, including the most aggressive forms of the childhood tumors, neuroblastoma and ...crest tumors nor tumors of the central nervous system, but ...
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BROMOCRIPTINE IN OBSTETRICS AND GYNAECOLOGY
... secreting pituitary tumors, and has been used with varying degrees of success in the treatment of menstrual disorders, premenstrual syndrome and polycystic ovarian ...
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Assessment of Hemorrhage in Pituitary Macroadenoma by T2* Weighted Gradient Echo MR Imaging
... and pituitary tumors per- formed the histologic assessment of the hem- orrhage in the whole surgical specimens, independent of the other participants and completely unaware of the clinical and neuro- ...
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Hartlmüller, Daniela (2018): The effects of temozolomide on normal and tumoral pituitary cells. Dissertation, LMU München: Medizinische Fakultät
... Right now, temozolomide is only used in cases, where other treatment options already failed. Due to the low rate of side effects, it seems warranted to discuss the initiation of temozolomide at an earlier point of time. ...
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E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression
... in pituitary adenomas? The affirmative answer comes once again from the study of the HMGA2 transgenic ...fact, pituitary adenomas excised from these mice were used in EMSA assays to analyze the E2F1-DNA ...
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Ten-Year Follow-Up of Collision Tumors Composed of Craniopharyngioma and Pituitary Adenoma: A Case Report and Literature Review
... depressed, and right hemiplegia appeared acutely. There- fore, the patient first underwent an emergency operation on the suprasellar tumor and cyst to decrease the in- tracranial pressure. We chose a left pterional ...
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Pituitary directed leukemia inhibitory factor transgene forms Rathke's cleft cysts and impairs adult pituitary function A model for human pituitary Rathke's cysts
... The degree of growth retardation observed in these trans- genic animals is greater than that seen in other models in which somatotroph lineage was ablated using either thymidine kinase (25) or diphtheria toxin (26), or ...
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Heparin binding secretory transforming gene (hst) facilitates rat lactotrope cell tumorigenesis and induces prolactin gene transcription
... Hormone secretion. Primary cultures of rat pituitary cells treated with FGF-4 for 14 and 20 h exhibited increased PRL secretion by 60% (P , 0.05) and 37% (P , 0.025), respectively (Fig. 3). This stimulatory effect ...
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Differential expression of microRNAs in GH-secreting pituitary adenomas
... in pituitary tumori- genesis ...of pituitary adenomas remains largely ...GH-secreting pituitary adenomas samples and normal pituitary samples by miRCURY™ Locked Nucleic Acid Array in order to ...
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