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Platelet Aggregation

A revised model of platelet aggregation

A revised model of platelet aggregation

... that platelet aggregation in vivo is a dynamic process in which platelets in flowing blood continuously tether, translocate, and/or detach from the luminal surface of a developing thrombus, with only a ...

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Viscum album L. & Abies alba borisii regis effects on platelet aggregation and tumor metastasis

Viscum album L. & Abies alba borisii regis effects on platelet aggregation and tumor metastasis

... [adenosine diphosphate (ADP), platelet- activating factor (PAF), and arachidonic acid (ARA)]. The agonists’ concentration was adjusted to cause maximum, irreversible accumulation in control platelets. Apart from ...

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Role of thrombospondin in platelet aggregation

Role of thrombospondin in platelet aggregation

... Thrombospondin (TSP), the major alpha-granule protein of human platelets, binds to the activated platelet surface upon platelet stimulation. TSP has hemagglutinating (lectin-like) activity and forms a ...

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The Effects of vanilloid like agents on platelet aggregation

The Effects of vanilloid like agents on platelet aggregation

... Platelets play an important role in thrombogenesis, with antiplatelet medications such as the cyclooxygenase inhibitors, the most effective drugs for the treatment and prevention of atherothromobotic diseases (Patrono et ...

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Inhibition of platelet aggregation by apolipoprotein E

Inhibition of platelet aggregation by apolipoprotein E

... decreases platelet function by the same pathway ...f platelet N O w ithout agonist ...their platelet population [318, ...during platelet aggregation induced by this agonist [295, ...

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Immunoinhibition of ristocetin induced platelet aggregation

Immunoinhibition of ristocetin induced platelet aggregation

... This aggregation response is abolished after digestion of the fixed platelets with ...ristocetin-induced aggregation of fixed washed platelets in buffer and normal platelets in platelet-rich ...a ...

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Human platelet aggregation is initiated by peripheral blood mononuclear cells exposed to bacterial lipopolysaccharide in vitro

Human platelet aggregation is initiated by peripheral blood mononuclear cells exposed to bacterial lipopolysaccharide in vitro

... induce platelet aggregation. Induction of platelet aggregation required the generation of thrombin dependent on coagulation Factors VII, X, and II, and ...

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Defective Ristocetin Induced Platelet Aggregation in von Willebrand's Disease and its Correction by Factor VIII

Defective Ristocetin Induced Platelet Aggregation in von Willebrand's Disease and its Correction by Factor VIII

... ristocetin-induced platelet aggregation correlated well with the degree of abnormality of the bleeding time and the levels of antihemophilic factor (AHF, VIII AHF ) procoagulant ...ristocetin-induced ...

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Multiscale Modelling Of Platelet Aggregation

Multiscale Modelling Of Platelet Aggregation

... Bleeding could result from inactivation of platelets or acute injury. When bleeding occurs, blood is flowing through the clot into the surrounding tissue or air. The pressure drop between the blood and the interstitial ...

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Platelet aggregation, mean platelet volume and plasma fibrinogen as risk factors for acute myocardial infarction

Platelet aggregation, mean platelet volume and plasma fibrinogen as risk factors for acute myocardial infarction

... on platelet aggregation testing with ADP as agonist on optical ...mean platelet aggregation (%) in cases of AMI (n=30) was ...a platelet aggregability of ≥49% on optical aggregometry ...

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The Effects of Cell Surface Proteins and Redox State on Platelet Aggregation and Adhesion

The Effects of Cell Surface Proteins and Redox State on Platelet Aggregation and Adhesion

... the platelet reaction of aggregation and ...on platelet aggregation and ...on platelet aggregation were statistically significant, the trends do reliably ...

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Effects of antiphospholipid antibodies on in vitro platelet aggregation

Effects of antiphospholipid antibodies on in vitro platelet aggregation

... that platelet hyperfunction (as measured by platelet aggregation) is present in patients with antiphospholipid antibodies, 8 sug- gesting an important role for platelets in the development of ...

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Effect of Heparin and Heparin Fractions on Platelet Aggregation

Effect of Heparin and Heparin Fractions on Platelet Aggregation

... induced aggregation of platelets in citrated platelet-rich plasma and enhanced platelet aggregation and serotonin secretion induced by other ...elevate platelet cyclic AMP and by EDTA ...

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Plasmin Induced Platelet Aggregation and Platelet Release Reaction  EFFECTS ON HEMOSTASIS

Plasmin Induced Platelet Aggregation and Platelet Release Reaction EFFECTS ON HEMOSTASIS

... caused aggregation of a suspension of washed platelets from human, rabbit, or pig ...The platelet aggregation was reversible, but it was accompanied by a significant release of adenine nucleotides, ...

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Interrelations of Platelet Aggregation and Secretion

Interrelations of Platelet Aggregation and Secretion

... of platelet stimulus-response coupling that includes two mechanisms for activation; aggregation-mediated activation is inhibited by indomethacin, while direct activation does not depend upon ...

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A Circulating Inhibitor of Platelet Aggregation in Bartter's Syndrome

A Circulating Inhibitor of Platelet Aggregation in Bartter's Syndrome

... Conversely, to rule out the possibility of an intrinsic platelet defect, platelets from the two teen-aged patients were washed’#{176}, put in normal PPP, and studied for aggregation befo[r] ...

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Prostacyclin and Platelet Aggregation in Sickle Cell Disease

Prostacyclin and Platelet Aggregation in Sickle Cell Disease

... Patients with sickle cell disease have certain platelet function abnormalities that may relate to vaso-occlusive episodes.’4 Various abnormalities of platelet function include increased [r] ...

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Impact of platelet count on results obtained from multiple electrode platelet aggregometry (Multiplate™)

Impact of platelet count on results obtained from multiple electrode platelet aggregometry (Multiplate™)

... after platelet activation Multiplate™ analyzer records impedance between two electrodes during a period of six minutes reflecting platelet aggregation on the surface of the ...of aggregation ...

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Specifics of Platelet Hemostasis in Children with Chronic Diseases of Lungs

Specifics of Platelet Hemostasis in Children with Chronic Diseases of Lungs

... of platelet aggregation function can help early diagnostics of microvasculature’s ...platenet aggregation activity in children with chronic ...The platelet aggregation in children’s ...

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Effect of common agonists on cytoplasmic ionized calcium concentration in platelets  Measurement with 2 methyl 6 methoxy 8 nitroquinoline (quin2) and aequorin

Effect of common agonists on cytoplasmic ionized calcium concentration in platelets Measurement with 2 methyl 6 methoxy 8 nitroquinoline (quin2) and aequorin

... to platelet activation, we studied the correlation of platelet aggregation and ATP secretion with [Cai2+] as determined by 2-methyl-6-methoxy 8- nitroquinoline (quin2) and aequorin in response to ...

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