Platelet aggregation and secretion
Rac1 mediated signaling plays a central role in secretion dependent platelet aggregation in human blood stimulated by atherosclerotic plaque
... in secretion and subsequent platelet aggregation in blood upon activation by a wide array of platelet sti- muli including atherosclerotic ...prevented platelet secretion from ...
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Interrelations of Platelet Aggregation and Secretion
... monitors aggregation and secretion in the same sample of plateletrich ...ADP, secretion began only after aggregation was almost ...biphasic aggregation was observed, and ...
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Role of thrombospondin in platelet aggregation
... in platelet macroaggregates and an increase in microaggregates and nonaggregated single ...ADP-induced platelet aggregation but caused rapid platelet disaggregation with the abolition of the ...
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Platelet adhesion and aggregation at sites of vascular
... and aggregation at sites of vascular injury is crucial to arrest bleeding but can also lead to occlusion of diseased vessels by thrombus formation and potentially fatal ...granule secretion, and exposure of ...
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The Effects of vanilloid like agents on platelet aggregation
... different platelet species and various volunteer ...on platelet aggregation, depending on the agonist ...change, secretion, TxA 2 formation and aggregation, and also increases ...
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Effect of Heparin and Heparin Fractions on Platelet Aggregation
... induced aggregation of platelets in citrated platelet-rich plasma and enhanced platelet aggregation and serotonin secretion induced by other ...elevate platelet cyclic AMP and by ...
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Platelet Aggregation Testing in Platelet-Rich Plasma Description of Procedures With the Aim to Develop Standards in the Field
... 37 platelet aggregation tests with abnormal results, 12 patients had an aspirin-like defect characterized by an abnormal arachidonic acid response and variable defects in response to ADP and/or ...weak ...
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PKCα regulates platelet granule secretion and thrombus formation in mice
... lating platelet secretion of α-granules, biogenesis and secretion of dense granules, regulation of integrin α IIb β 3 , and thrombus formation in vitro and in ...regulates platelet ...
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Functional Features of Platelet Secretion in Piglets During Early Ontogenesis
... the platelet (Table ...of platelet aggregation under the influence of a strong inducer during the first year of life in the observed piglets also gradually grew by a total of ...
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Activation of Rabbit Platelets by Platelet Activating Factor Derived from IgE Sensitized Basophils: CHARACTERISTICS OF THE AGGREGATION AND ITS DISSOCIATION FROM SECRETION
... https://doi.org/10.1172/JCI108799. Platelet-activating factor (PAF) is liberated from antigen-stimulated, IgE-sensitized rabbit basophils and induces aggregation of platelets and secretion of their ...
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A revised model of platelet aggregation
... that platelet aggregation in vivo is a dynamic process in which platelets in flowing blood continuously tether, translocate, and/or detach from the luminal surface of a developing thrombus, with only a ...
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Multiscale Modelling Of Platelet Aggregation
... predicted platelet signaling and deposition based on spatiotemporal exposure to agonists in the event of a hypothetical rupture of vessel wall at the post-stenotic ...the platelet flux, biological signaling ...
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Gastric secretion of platelet activating factor and
... 14 Several hormones may stimulate platelet activating factor biosynthesis in vitro.9 1 In the cat, histamine stimulates both gastric acid and platelet activating factor in vivo.'4 Gastri[r] ...
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Influence of flavonoids’ lipophilicity on platelet aggregation
... on platelet aggregation Flavonoids are natural polyphenolic compounds present in a wide spectrum of plants that have a beneficial effect on human ...on platelet aggrega- tion when measured by ...
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Immunoinhibition of ristocetin induced platelet aggregation
... Human platelets washed and fixed in paraformaldehyde aggregate in the presence of the antibiotic ristocetin and normal plasma. This aggregation response is abolished after digestion of the fixed platelets with ...
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Inhibition of platelet aggregation by apolipoprotein E
... convenient model system for identifying and characterising signalling pathways [3-5], I sought to delineate the molecular influences that apoE might exert. I initially verified that apoE purified from plasma was a highly ...
208
Plasmin Induced Platelet Aggregation and Platelet Release Reaction EFFECTS ON HEMOSTASIS
... caused aggregation of a suspension of washed platelets from human, rabbit, or pig ...The platelet aggregation was reversible, but it was accompanied by a significant release of adenine nucleotides, ...
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Prostacyclin and Platelet Aggregation in Sickle Cell Disease
... Patients with sickle cell disease have certain platelet function abnormalities that may relate to vaso-occlusive episodes.’4 Various abnormalities of platelet function include increased [r] ...
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A Circulating Inhibitor of Platelet Aggregation in Bartter's Syndrome
... Conversely, to rule out the possibility of an intrinsic platelet defect, platelets from the two teen-aged patients were washed’#{176}, put in normal PPP, and studied for aggregation befo[r] ...
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Effects of antiphospholipid antibodies on in vitro platelet aggregation
... affect platelet aggregation, consistent with the previous work of our ...13 Platelet-rich plasma (PRP) was obtained follow- ing centrifugation for 10 minutes at 150g at 20 ...C. Platelet-poor ...
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