Plexin-B
Original Article ERα and ERβ oppositely regulated plexin B1 expression and migration of ovarian cancer SKOV-3 cells
... of plexin B1 was excluded due to the cell vitality (Supplementary Figure ...the plexin B1 was involved in ovarian cancer and mediated by the ER ...the plexin B1 expression. Furthermore, the ...
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Plexin-B2 promotes invasive growth of malignant glioma
... The Plexin-B2 knockdown nearly abolished the synergistic effect of SEMA4C-Fc/HGF on Met phosphorylation, confirming that this effect is mediated by Plexin-B2 ...
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A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis
... for plexin B1 and co- staining for a marker for metanephrogenic mesenchyme, WT1, we found a clear complementarity of plexin B1 expression and WT1- stained condensing mesenchyme ...reported plexin B1 ...
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ErbB 2 signals through Plexin B1 to promote breast cancer metastasis
... encoding Plexin-B1 strongly reduced the occurrence of ...of Plexin-B1 expression correlated with good ...that Plexin-B1 represents a new candidate therapeutic target for treating patients with ...
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Drosophila Plexin B is a Sema 2a receptor required for axon guidance
... for plexin-mediated axonal repulsion, PlexA may be able to substitute in a limited fashion for PlexB through its ability to recruit MICAL and mediate repulsion of ISNb ...
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Label-free quantitative mass spectrometry analysis of differential protein expression in the developing cochlear sensory epithelium
... reticulocalbin-1, plexin-B2, and low-density lipoprotein receptor-related protein 2, which are involved in the de- velopment of sensory organs [49] and nervous system [50, 51] and thus may contribute to the ...
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Neuroimmune Semaphorin 4A in Cancer Angiogenesis and Inflammation
... and Plexin D1 expression ...receptors, Plexin D1 and VEGF-R1, and mediate this loop’s signaling ...(16), Plexin B1 to induce such effect in human Treg cells (our unpublished observations), Tim-2 to ...
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The involvement of Rho GTPases in plexin mediated signal transduction
... molecule. Plexin-Bl is synthesised as a 300 kDa single chain ...of Plexin-Bl). Plexin-Bl is only cleaved upon arrival at the cell ...f Plexin-Bl that fail to interact with PDZ-RhoGEF or Rac 1 ...
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Conversion of cell movement responses to Semaphorin 1 and Plexin 1 from attraction to repulsion by lowered levels of specific RAC GTPases in C elegans
... The sequence of linkage group IV, determined by the Sanger Center C. elegans consortium, revealed the plx-1 gene Y55F3AL.1, which encodes a Plexin 1 homolog (see also Fujii et al., 2002). A full-length cDNA of 5.8 ...
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Roles of Semaphorin 6B and Plexin A2 in Lamina Restricted Projection of Hippocampal Mossy Fibers
... that plexin-A1 (Ohta et al., 1995) and plexin-B3 (Hartwig et ...of plexin-B3 enhances neurite outgrowth of cerebellar neurons (Hartwig et ...that plexin-A1 functions as not only a recep- tor ...
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Analysis of zebrafish sidetracked mutants reveals a novel role for Plexin A3 in intraspinal motor axon guidance
... chemorepulsion of motor axon growth cones from posterior somites by semaphorin ligands. (A,B) Chimera analysis. Donor cells are labeled with rhodamine dextran (red) and donor motoneurons express GFP (green); hosts ...
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Plexin D1/Semaphorin 3E pathway may contribute to dysregulation of vascular tone control and defective angiogenesis in systemic sclerosis
... Fig. 6 In vitro angiogenesis assay results. Upper panel: representative images of capillary morphogenesis on Matrigel after 24 hours. Lower panel: capillary morphogenesis of healthy and systemic sclerosis (SSc) dermal ...
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Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort
... Objective: Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epi‑ thelium derived factor, is expressed in many tissues including the ...
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Vulva morphogenesis involves attraction of plexin 1 expressing primordial vulva cells to semaphorin 1a sequentially expressed at the vulva midline
... migration during vulva morphogenesis. (A) Lateral perspective; D, dorsal; P, posterior; unlabelled arrow indicates left-right depth. A series of short-range migrations is repeated for the formation of vulva rings. ...
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On Locally b#-Closed Sets and Weakly b#-Closed Sets
... a b # -open set containing ...weakly b # ...a b # -open set containing ...weakly b # -closed. But the reverse is not true as shown below. Let B= (2, 3) in ...Then B G=[2, 3] and ...
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Therapeutic efficacy of a novel humanized antibody-drug conjugate recognizing plexin-semaphorin-integrin domain in the RON receptor for targeted cancer therapy
... Both H5B14-MMAE and H5B14-DCM at 20 mg/kg in a single injection regimen were evaluated in mouse xeno- graft tumor models initiated by H358, HT-29, L3.6pl, and T-47D cell lines. LoVo cells served as the control. Injection ...
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Obama inaugural address 2
... And so to all other peoples and governments who are watching today, from the grandest capitals to the small village where my father was born: know that America is a friend of each nat[r] ...
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The Daily Scoop 2017
... He thought that his wife’s primary condition of neurological disease had simply taken an awful turn and that there were no other factors of significance in this particular case.. This la[r] ...
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Irish, Scottish, Welsh assignment
... 'Welsh is an official British language, the oldest language in Europe and the most common in Britain after English.' Photograph: David Hunter/Robert Harding /REX.. Last weekend I took [r] ...
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ShootinganElephanttext
... The older men said I was right, the younger men said it was a damn shame to shoot an elephant for killing a coolie, because an elephant was worth more than any damn Coringhee coolie. An[r] ...
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