polymer-free drug-eluting stent
Novel drug-eluting stents in the treatment of de novo coronary lesions
... (Biosensors) stent is a stainless steel polymer-free stent, currently under development and releas- ing Biolimus A9™, a rapamycin derivate with immuno- suppressive and antiproliferative ...
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Some design considerations for polymer-free drug-eluting stents : a mathematical approach
... small drug-containing mesh-like devices are now routinely insert- ed into arteries which have become dangerously narrowed due to a condition known as ...Subsequent stent designs included an ...
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Modelling arterial wall drug concentrations following the insertion of a drug-eluting stent
... the drug in the polymer is in a single phase which is per- mitted to freely ...of drug in the polymer is below solubility, in which case the dissolution of drug can be re- garded as ...
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Nanoparticle Drug- and Gene-eluting Stents for the Prevention and Treatment of Coronary Restenosis
... BioFreedom Drug-Eluting Coronary Stent Delivery System (Biosensors Inc, Newport Beach, Calif) is composed of 3 key components, including a 316 L stainless steel platform that has been modified with a ...
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A novel polymer-free ciglitazone-coated vascular stent: in vivo and ex vivo analysis of stent endothelialization in a rabbit iliac artery model
... Vascular drug-eluting stents (DES) with a metallic or bioresorbable backbone have proven superiority compared to bare metal stents (BMS) with respect to long-term patency and reduced restenosis rates ...or ...
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Original Article Histological validation of frequency domain optical coherence tomography for the evaluation of neointimal formation after a novel polymer-free sirolimus-eluting stent implantation
... Novel polymer-free drug-eluting stents have been developed to reduce polymer-related adverse ...after polymer-free DES implantation is unclear and validation between ...
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Five-year clinical outcomes in patients with diabetes mellitus treated with polymer-free sirolimus- and probucol-eluting stents versus second-generation zotarolimus-eluting stents: a subgroup analysis of a randomized controlled trial
... a polymer-free dual drug sirolimus- and probucol-eluting stent (backbone Yukon stent, Trans- lumina, Hechingen, Germany; stent currently commer- cially available as ...
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The benefits of drug-eluting stents in the treatment of coronary artery disease
... Subsequently, drug-eluting stents (DES) were introduced, which had the added advantage of releasing an anti-proliferative drug from the stent to reduce the neointimal proliferation, thus ...
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Modeling arterial wall drug concentrations following the insertion of a drug-eluting stent
... with drug elution from stents into arterial ...nonerodible polymer coated Cypher sirolimus-eluting ...particular stent system because it contains a drug-filled polymer coating and ...
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Original Article The overlap nano-porous polymer-free sirolimus-eluting stent in swine model evaluated by optical coherence tomography and histopathology
... ple stent placement as well as overlapping stents were identified as the risk factors of restenosis [5, 6, 10, ...that polymer-free sirolimus-eluting stents and polymer-free ...
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Next generation drug-eluting stents: focus on bioabsorbable platforms and polymers
... between stent groups in terms of death/MI or stent ...novel polymer-free drug dosing, while maintaining high antirestenotic ...Coronary Stent to the ...
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Biodegradable polymer Biolimus-eluting stent (Nobori<sup>®</sup>) for the treatment of coronary artery lesions: review of concept and clinical results
... continued at least 3 months after the procedure. From May to October, 2011, in 98 Japanese centers, 3,235 patients were randomized 1:1 without any exclusion criteria to undergo PCI with either the BES or the EES. ...
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Comparison of a drug eluting balloon first and then bare metal stent with a drug eluting stent for treatment of de novo lesions: study protocol of a randomized controlled trial
... silorimus-eluting stent implantation was demonstrated [3,4]. In this study, in-stent neoather- osclerosis was considered an important mechanism ...
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A three-dimensional mathematical model for drug delivery from drug-eluting stents
... a drug that is slowly eluted to prevent the growth of scar tissue in the artery ...flow. Drug-eluting stents are safe and effective in most circumstances, having a lower rate of restenosis than bare- ...
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First-generation versus second-generation drug-eluting stents in current clinical practice: updated evidence from a comprehensive meta-analysis of randomised clinical trials comprising 31 379 patients
... In the present meta-analysis, which compared most robust evidence of fi rst-generation versus second- generation DES data, second-generation EES was found to be superior in regard to safety end points as com- pared with fi ...
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Comparison of the safety and efficacy of biodegradable polymer drug-eluting stents versus durable polymer drug-eluting stents: a meta-analysis
... DESs produces significantly higher incidences of adverse events, such as stent thrombosis (ST) [10]. The inci- dence of ST is relatively low; nonetheless, this issue has attracted widespread concern because the ...
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Polyurethane membrane with porous surface for controlled drug release in drug eluting stent
... PTX (50 mg) was added into 10 mL of PU solution con- taining various amount of PEG. PTX loaded porous PU membrane was fabricated by above-mentioned method. To investigate drug release profile, approximately 0.46 ...
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Impact of Coronary Plaque Characteristics on Late Stent Malapposition after Drug Eluting Stent Implantation
... summarized in Table 1 and 2. Follow-up OCT characteristics are summarized in Table 3. Pre-procedural absolute total NC and DC plaque volumes were positively correlated with the percentage of malapposed struts (r=0.44, ...
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Comparisons of the Effects of Stent Eccentricity on the Neointimal Hyperplasia between Sirolimus Eluting Stent versus Paclitaxel Eluting Stent
... SE was defined as minimum stent diameter divided by maximum stent diameter. We investigated three different SE parameters defined as follows: 1) SE determined at the lesion site with maximal %NIH area on ...
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Everolimus-eluting stents in interventional cardiology
... sirolimus-eluting stent was superior to the paclitaxel-eluting stent for prevention of resteno- sis, the study was designed to assess noninferiority of the zotarolimus-eluting ...
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