Polymeric Micelles
<p>Novel pH-Sensitive Urushiol-Loaded Polymeric Micelles for Enhanced Anticancer Activity</p>
... developing micelles that are sensitive to tumor microenvironmental stimuli or signals, such that drug release is controlled in a targeted ...meric micelles have been found to be promising owing to the ...
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Enhancing oral bioavailability of quercetin using novel soluplus polymeric micelles
... nanosized polymeric micelles based on amphiphilic polymers soluplus using a modified film dispersion ...novel polymeric micelles as delivery systems for bio- active ...
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Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia
... in polymeric micelles prepared by microfluidics on fetal hemoglobin production by erythroid precursor cells from a β-thalassemia ...in polymeric micelles prepared by ...in polymeric ...
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Stimuli-responsive polymeric micelles for drug delivery and cancer therapy
... Abstract: Polymeric micelles (PMs) have been widely investigated as nanocarriers for drug delivery and cancer treatments due to their excellent physicochemical properties, drug loading and release ...
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Pulmonary delivered polymeric micelles pharmacokinetic evaluation and biodistribution studies
... intact micelles across 441 the air–blood barrier, confocal microscopy was utilized to evaluate 442 the distribution of IV and IT micelles in brain ...co-loaded micelles were given to rats by either ...
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Multispectral optoacoustic tomography (MSOT) for imaging the particle size-dependent intratumoral distribution of polymeric micelles
... of micelles in tumor tissues in a spatiotemporal manner with a reasonable spatial ...of micelles in tumor tissues, MSOT imag- ing in the central and border parts of tumor tissues was used to indicate ...
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Lx2-32c–loaded polymeric micelles with small size for intravenous drug delivery and their inhibitory effect on tumor growth and metastasis in clinically associated 4T1 murine breast cancer
... Lx2-32c–loaded polymeric micelles (Lx2-32c-PMs) with small size and investi- gated their antitumor efficacy against tumor growth and metastasis on 4T1 murine breast cancer cell line with Cremophor EL–based ...
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ENTRAPMENT OF SEED EXTRACT OF NIGELLA SATIVA INTO THERMOSENSITIVE (NIPAAM–CO–VP) CO-POLYMERIC MICELLES AND ITS ANTIBACTERIAL ACTIVITY
... this polymeric system to check the release of the bioactive compound and evaluated its antibacterial ...the polymeric micelle and its effectiveness has been evaluated against gram positive strain of ...
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Enhanced Therapeutic Effect of RGD-Modified Polymeric Micelles Loaded With Low-Dose Methotrexate and Nimesulide on Rheumatoid Arthritis
... It has been reported that the use of NSAIDs partially alleviates the symptoms of rheumatoid arthritis but cannot prevent its long-term disease progression [43]. Therefore, nimesulide did not lead to a significant ...
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Formulation and In-Vitro Evaluation of Raloxifene Hydrochloride Loaded Mixed Pluronic L121/F127 Polymeric Micelles
... formulate micelles. Micelles formed from copolymers tend to have a relatively narrow size distribution compared to standard surfactant ...CMCs, polymeric micelles are relatively insensitive to ...
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Doxorubicin-incorporated polymeric micelles composed of dextran-<em>b</em>-poly(DL-lactide-co-glycolide) copolymer
... the polymeric micelles was observed using a transmission electron micro- scope (TEM, JEOL JEM-2000 FX II, ...of polymeric micelle solution containing phosphotungstic acid ...the polymeric ...
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Two-photon AIE luminogen labeled multifunctional polymeric micelles for theranostics
... novel polymeric micelles based on mPEG-SS-Poly (AEMA-co-TBIS) (mPEATss) copolymer with two-photon excitable AIE fluorescence probe equipped with pH and redox-dual triggered drug release as well as ...
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In Vitro Evaluation of Theranostic Polymeric Micelles for Imaging and Drug Delivery in Cancer
... [14] Polymeric micelles are self-assembled amphiphilic copolymers in the form of core/shell ...the micelles has been used ex- tensively for encapsulation of various non-polar drugs like paclitaxel, ...
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Radiolabeling polymeric micelles for in vivo evaluation: a novel, fast, and facile method
... of polymeric micelles have already led to clinical applications for systemic chemotherapy [6, ...the micelles to the desired site is essential for therapeutic success, which can be accomplished by ...
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Biodegradable polymeric micelles coencapsulating paclitaxel and honokiol: a strategy for breast cancer therapy in vitro and in vivo
... poly(caprolactone) micelles (P–H/M) by solid dispersion method against breast ...in micelles, the release of PTX or HK showed a sustained behavior in ...PTX-loaded micelles or HK-loaded ...
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Formulation and evaluation of mixed polymeric micelles of quercetin for treatment of breast, ovarian, and multidrug resistant cancers
... molecule. Polymeric micelles (PMs) is a novel drug delivery system having characteristics like smaller particle size, higher drug loading, sustained drug release, high stability, increased cel- lular uptake ...
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Polymeric micelles for potentiated antiulcer and anticancer activities of naringin
... study, polymeric micelles of naringin based on pluronic F68 (PF68) were developed, fully characterized, and ...1:50 micelles with the mean diameter of ...These micelles showed the highest ...
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RGD peptide-mediated chitosan-based polymeric micelles targeting delivery for integrin-overexpressing tumor cells
... (PEG-CS-SA) micelles via chemical reaction in the presence of N,N′-Disuccinimidyl ...the polymeric micelles was determined by measuring the fluorescence intensity of pyrene as a fluorescent ...
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Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood–brain barrier
... In the brain, DPX elimination can be decreased by the micelles due to a delay in residency time. At 1.5 h after administration, DPX concentration from the PM formulas reached a maximum concentration (242.96 ± 21.1 ...
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Fisetin and polymeric micelles encapsulating fisetin exhibit potent cytotoxic effects towards ovarian cancer cells
... fisetin micelles to improve its physical ...fisetin micelles demonstrated superior anti- tumor ...fisetin micelles due to the excellent properties of this ...MPEG-PCL micelles ...
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