positional cloning
Positional cloning of rp2 QTL associates the P450 genes CYP6Z1, CYP6Z3 and CYP6M7 with pyrethroid resistance in the malaria vector Anopheles funestus
... A positional cloning approach was used to identify genes conferring resistance in the uncharacterised rp2 quantitative trait locus (QTL) previously detected in this vector using F6 advanced intercross lines ...
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Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole genome sequencing
... In designing the BSFseq and HMFseq strategies, we also considered sequencing the wild-type siblings. For the BSFseq mapping of jj410 we did sequence wild-type siblings and the subtraction of its homozygous SNPs from the ...
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The positional cloning of Fv-1, a mouse retroviral restriction gene
... C arbon, 1980; M u rray an d Szostak, 1983). A n au to n o m o u s rep licatio n sequence (ARS) contains a functional origin of replication w hich initiates replication only once d u rin g the cell cycle (Stinchcomb et ...
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Towards positional cloning of the autosomal dominant doyne honeycomb retinal dystrophy (DHRD) gene localised to chromosome 2p16
... gene cloning techniques that has been witnessed in recent years has led to the cloning of many o f the genes associated with retinal degenerations and disorders ...
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Towards positional cloning of the gene responsible for autosomal dominant retinitis pigmentosa mapped to chromosome 19q13.4
... PI cloning system: The PI cloning system complements cosmid and Y AC cloning systems by offering an intermediate range o f clonable genomic fragment sizes along with the ability to isolate from ...
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Biochemical characterization and positional cloning of the var2 variegation mutant of Arabidopsis thaliana
... For example, if VARl expression were limited to cells in the expanding leaf, enhanced rates of cell and plastid division during the expansion phase could result, in the mutant background[r] ...
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The positional cloning and expression studies of the IMMUTANS variegation locus of Arabidopsis thaliana
... THE IMMUTANS VARIEGATION LOCUS OF ARABIDOPSIS DEFINES A MITOCHONDRIAL ALTERNATIVE OXIDASE HOMOLOG THAT FUNCTIONS DURING EARLY CHLOROPLAST BIOGENESIS A paper published in The Plant Cell 1[r] ...
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Tracing the Emergence of a Novel Sex-Determining Gene in Medaka, Oryzias luzonensis
... Here, we used positional cloning to search for the sex-determining gene in Oryzias luzonensis and found that Gsdf Y (gonadal soma derived growth factor on the Y chromosome) has replaced [r] ...
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Genetic epidemiology of diabetes
... mapping, positional cloning, and candidate gene studies have been most successful in the forms of diabetes with the sim- plest genetic ...of positional cloning and studies of positional ...
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Formation of the retinotectal projection requires Esrom, an ortholog of PAM (protein associated with Myc)
... By positional cloning, allele sequencing and morpholino injection, we have established that Esrom is an ortholog of PAM/Highwire/RPM-1. PAM was initially identified in a biochemical screen for proteins ...
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Biological insights through genomics: mouse to man
... a positional cloning project is appropriately a cause for celebra- tion, but invariably, is just an important step in a long journey which began with the identification of the abnormal pheno- type and ...
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Mutations in the protein kinase A R1α regulatory subunit cause familial cardiac myxomas and Carney complex
... We have now refined the CAR interval and used a positional cloning strategy to demonstrate that familial cardiac myxomas and Carney complex are caused by mutations in the gene PRKAR1α en[r] ...
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Approaches for Improved Positional Proteomics
... Another approach we took to boost the identification confidence is by exploiting iTRAQ (isobaric tag for relative and absolute quantitation) in the positional proteomics workflow. This approach allows for ...
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Cognitive Outcomes and Positional Plagiocephaly
... To evaluate case-control differences by severity of skull deformation, we repeated these analyses for children who had mild PPB in infancy versus controls and those who had moderate to s[r] ...
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Ligand-Gated Ion Channels in Sensory Neurons
... Molecular Cloning of a Human Neuronal Nicotinic Acetycholine Receptor p3-like Subunit. Molecular Cloning of a Resiniferatoxin-binding Protein.[r] ...
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Product Proliferation and Pricing in a Market with Positional Effects
... is available, consumers who would normally purchase the inferior product are no aware of more advanced features and capabilities; the more people purchase the better product, the more likely it is that other consumers ...
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Positional Non-Cooperative Equilibrium
... Abstract This paper presents and analyses a game theoretic model for resource allocation, where agents are status-seeking and consuming positional goods. We propose a unified framework to study the competition for ...
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Intra-Positional and Inter-Positional Differences in Somatotype Components and Proportions of Particular Somatotype Categories in Youth Volleyball Players
... There have been no studies that investigated intra-positional differences according to performance level. Such studies could provide volleyball coaches with useful indications to better detect talents for ...
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Positional Preferences: Efficiency and Distortions under Welfarist and Paternalistic Governments
... of positional preferences and about optimal redistributive taxation? Third, how do the results presented in this study change in a model with an endogenous ...
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Late Cerebellar Vermis Metastasis of Breast Cancer Presenting as Pseudo- Benign Paroxysmal Positional Vertigo Comacchio F 1, Mion M*2 and Markova V 2
... Pseudo-BPPN can usually be identified after a full examination with brain imaging, since those type of nystagmus could be found in vascular cerebellar vermis lesion. Lesions of the malignant type are also located in ...
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