Pre-clinical studies
The efficacy of Epigallocatechin-3-gallate (green tea) in the treatment of Alzheimer’s disease: an overview of pre-clinical studies and translational perspectives in clinical practice
... and pre-clinical studies have demonstrated that EGCG, the principal bioactive component found in green tea, has anti-inflammatory properties by modulating different molecular ...vivo studies ...
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Capillary microsampling of mouse blood in pre-clinical studies: an alternative to dried blood spot sampling.
... in pre-clinical studies; it is easy to perform and readily integrates with automated liquid handling platforms with a much lower financial outlay compared to an automated DBS ...
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IMPORTANCE AND THE UNIQUE ASPECTS OF MODALITIES FOR CONDUCTING NON-CLINICAL AND PRE-CLINICAL STUDIES OF COMPARTMENTAL AND NON-COMPARTMENTAL ANALYSIS
... and pre-clinical studies are an exigent first step to assess the safety and quality of ingredients new to infant ...and pre-clinical studies must be based on the regulatory ...
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MP-1™ Polyimide for Medical Devices: 1. Pre Clinical Studies
... pilot clinical study conducted in New-Zealand with excellent 13y follow-up ...a clinical study of 100 patients in New ...the pre-clinical studies while Part 2 will deal with the ...
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Image-guided surgery using invisible near-infrared fluorescent light : from pre-clinical studies to clinical validation
... The BIDMC study team thanks Barbara L. Clough and Mireille Rosenberg for clinical trial preparation, Keith V. Belken from the BIDMC Investigational Pharmacy, Judith Hirshfield-Bartek for assistance with patient ...
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Neuroprotective effects of berberine in animal models of Alzheimer’s disease: a systematic review of pre clinical studies
... reveals about the underlying mechanism of the protective effects of berberine in animal AD models. We hope to provide more insightful information for future clinic trials. To perform the systematic review, we searched ...
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Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate
... for clinical relevance it is clear that the isolation, expansion and implantation of cells will need to be conducted at separate facilities, often with considerable distances between the cell production site and ...
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... epidemiological studies exploring the effects of adolescent cannabis exposure on later mental health trajectories are limited not only in terms of establishing causality, but also in terms of the identification of ...
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Pre Clinical and Clinical study on Azhal Keel Vayu
... to pre clinical studies (Acute and sub acutr toxicity studies) as per the protocol and the safety of the drug was ...chemical studies were done at the bio chemistry lab of National ...
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NOVEL ANTI-ARRHYHTMIC AGENTS
... ¾ It is novel agent in early clinical development for treatment of atrial fibrillation. ¾ It acts by blocking sodium & potassium channels. ¾ Pre-clinical studies have shown that it [r] ...
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Development of a bioactive polymeric drug eluting coronary stent coating using electrospraying
... It has been suggested that the thickness of the polymer coating impacts on the safety of the stent, with recent computational studies indicating that thicker coatings pose a greater risk of deformity. 13 Such ...
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Predischarge risk factors for predicting significant hyperbilirubinemia in term of infants
... Significant hyperbilirubinemia (SHB) requiring phototherapy was used as outcome assessment. SHB was defined as bilirubin levels that surpass or was within 1mg/dL (17µmol/L) of the hour-specific phototherapy treatment ...
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Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study.
... mandatory pre- treatment biopsies (6 cores targeted towards the MRI identified index lesion), biopsies at 2 months [if response or stable disease by RECIST ...MRI studies including matched DCE and DWI; ...
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Home-based preoperative rehabilitation (prehab) to improve physical function and reduce hospital length of stay for frail patients undergoing coronary artery bypass graft and valve surgery
... Patients seen in early preoperative assessment clinics were voluntarily enrolled into the prehab programme when listed for cardiac surgery. The inclusion criteria for the programme included those aged ≥65 years, undergo- ...
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Diffusion Weighted Imaging of Orbital Masses: Multi Institutional Data Support a 2 ADC Threshold Model to Categorize Lesions as Benign, Malignant, or Indeterminate
... not possible to reconstruct these data from the published re- sults of the other studies, either because of a small sample size or the way the data were summarized. In place of a meta- analysis, we attempted to ...
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Vol 7 (2016)
... other studies lower values of GLS have been identified in patients with late gadolinium enhancement (LGE) assessed by CMR, however they correlate poorly, and the addition of GLS to EF, showed no incremental ...
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... Two studies established the effect of Triphala on Streptococcus mutans by comparing its antibacterial efficacy with chlorhexidine. In a study conducted by Srinagesh J et al., there was a significant reduction in ...
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Cytokine-induced killer (CIK) cell therapy for patients with hepatocellular carcinoma: efficacy and safety
... 21 studies for the following reasons: 3 trials were excluded for being phase I clinical trials, 18 trials were excluded for being ...the clinical trials is shown in Figure ...III clinical ...
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A Study on Cegana Vaatham (சகன வாதம்)
... pharmacological studies of SVC have got good correlation with clinical study report presented in this ...The clinical study findings with this drug did not mention anything on the abnormal liver ...
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Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurologic function in a rat model of middle cerebral artery occlusion
... of studies have provided evidence that cell transplantation can lead to the repair of damaged brain tissue and functional recovery in pre- clinical stroke models [3-8], including transplantation of ...
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