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Preclinical research

An alternative pathway for preclinical research in fluid management

An alternative pathway for preclinical research in fluid management

... Further research is nevertheless needed to resolve the questions raised concerning the relationship between choice of resuscitation fluid and patient ...of preclinical research may be of value in ...

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Mouse models of breast cancer in preclinical research

Mouse models of breast cancer in preclinical research

... cancer research provide an essential approach to examine the mechanisms and genetic pathway in cancer progression and metastasis and to develop and evaluate clinical ...cancer research and anti-cancer drug ...

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Preclinical research of the experimental preparation “Ferosel T”

Preclinical research of the experimental preparation “Ferosel T”

... During the period of research on the determination of chronic toxicity of ferrocellus T, no probable changes in the behavior of experimental animals were observed (Table 4). The appetite of all experimental and ...

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Ramucirumab: preclinical research and clinical development

Ramucirumab: preclinical research and clinical development

... both preclinical and early clinical studies, ramucirumab has been tested in different tumor types either alone or in combination with ...significant preclinical and clinical studies that led to the ...

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Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research

Viscum album L. extracts in breast and gynaecological cancers: a systematic review of clinical and preclinical research

... for Research and Treatment of Cancer Quality of Life Questionnaire- Cancer; EORTC QLQ-BR23: European Organization for Research and Treatment of Cancer Quality of Life Breast Cancer Questionnaire; FACT-G: ...

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Preservation of allograft bone using a glycerol solution: a compilation of original preclinical research

Preservation of allograft bone using a glycerol solution: a compilation of original preclinical research

... At the five-year real time aging point, the compressive strength of GBP Cloward dowels was similar to the freeze-dried group ( p = 0.27) (Fig. 3 c); however, GPB demonstrated significant[r] ...

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Construction and application of service quality evaluation system in the preclinical research on cardiovascular implant devices

Construction and application of service quality evaluation system in the preclinical research on cardiovascular implant devices

... the research & development of cardiovas- cular implants ...company research and development staff (n = ...the preclinical develop- ment of cardiovascular implant devices is up to five-star ...

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Stem cell therapy for diabetic foot ulcers: a review of preclinical and clinical research

Stem cell therapy for diabetic foot ulcers: a review of preclinical and clinical research

... and preclinical research studies do not offer a consensus regarding the optimal type of stem cell that should be used, and there is also no established optimal route or protocol to deliver stem ...

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The Snark was a Boojum - reloaded

The Snark was a Boojum - reloaded

... In spite of its functional significance and widespread acknowledgement of its existence, variability tends to be actively combated by behavioural neuroscientists. Such opposition is openly declared in methodology ...

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Sex bias in basic and preclinical age-related hearing loss research

Sex bias in basic and preclinical age-related hearing loss research

... and preclinical research has clear and direct im- plications for translational research and clinical out- comes ...on preclinical research, and here particularly on ARHL ...

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New Mechatronic Systems for the Diagnosis and Treatment of Cancer

New Mechatronic Systems for the Diagnosis and Treatment of Cancer

... in preclinical research. A particular preclinical application, that could greatly benefit from the use of robotics is the development of an image-guided robotic system for needle ...

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Endorphinergic Attenuation of Distress by Concomitantly Enhancing Endogenous Opioid Release and Switching Opioid Receptor Signaling from an Excessively Excitatory to a Normal Inhibitory Mode

Endorphinergic Attenuation of Distress by Concomitantly Enhancing Endogenous Opioid Release and Switching Opioid Receptor Signaling from an Excessively Excitatory to a Normal Inhibitory Mode

... Shen’s preclinical research demonstrating that the com- bination of an Endorphin Enhancer with an Opioid Re- ceptor Switcher produces increased pain tolerance by enhancing inhibitory opioid receptor ...

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Preclinical septic shock research: why we need an animal ICU

Preclinical septic shock research: why we need an animal ICU

... in preclinical medical research with the goal of disease modeling and exploration of novel therapeutic ...of preclinical models and may contribute to preclinical research failure in ...

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Tracking the impact of translational research in psychiatry: state of the art and perspectives

Tracking the impact of translational research in psychiatry: state of the art and perspectives

... in research insti- tutions such as the National Institutes of Health (NIH), USA and academic institutions ...Biomedical research was performed mostly in laboratories by med- ical scientists, who also ...

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Sex Reporting in Preclinical Microbiological and Immunological Research

Sex Reporting in Preclinical Microbiological and Immunological Research

... in preclinical research (https: ...in Research) guidelines ...the research subjects and animals and of materials derived directly from them ...

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Brain Perfusion Imaging in Neonates: An Overview

Brain Perfusion Imaging in Neonates: An Overview

... Several preclinical research studies are also being conducted on drugs that may act synergistically or additively with hypothermia.11,12 Transfontanellar ultrasound and MR imaging provid[r] ...

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A psychological approach to providing self management education for people with type 2 diabetes : the diabetes manual

A psychological approach to providing self management education for people with type 2 diabetes : the diabetes manual

... broad research aims were to develop the Diabetes Manual, a type 2 diabetes self-management educational intervention, and associated programme for delivery in primary ...

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A proposal for a new PhD level curriculum on quantitative methods for drug development

A proposal for a new PhD level curriculum on quantitative methods for drug development

... have been discussed in [12], there is no unique definition of what core training a statistician should receive. Despite the lack of unique definition, a survey by the European Federation of Statistician in the ...

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Image analysis in light sheet fluorescence microscopy images of transgenic zebrafish vascular development

Image analysis in light sheet fluorescence microscopy images of transgenic zebrafish vascular development

... Abstract. The zebrafish has become an established model to study vas- cular development and disease in vivo. However, despite it now being pos- sible to acquire high-resolution data with state-of-the-art fluorescence ...

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Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine

Preclinical Efficacy of a Lipooligosaccharide Peptide Mimic Candidate Gonococcal Vaccine

... In light of the importance of complement-dependent killing for the activity of MAb 2C7 in vivo (18), serum bactericidal assays were performed to assess functionality of immune antibodies. During the course of the antigen ...

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