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profiling studies

Handling of Clinical Tissue Specimens for Molecular Profiling Studies

Handling of Clinical Tissue Specimens for Molecular Profiling Studies

... molecular profiling studies We are continuing to investigate the types of molecular analyses that can be performed on ethanol-fixed samples, including the use of ethanol-fixed tissue for use on cDNA ...

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ISSR marker based DNA profiling studies in Rauwolfia species

ISSR marker based DNA profiling studies in Rauwolfia species

... The genomic DNA isolated from R.tetraphylla, R.serpentina, R.pentaphylla, R.micrantha and R.vomitoria ranged between 1.6 to 3.4 µg. Gurudeeban et al., (2011), also isolated 1.5-2.5 µg of DNA from Suaeda sp of Apocynaceae ...

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Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast

Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast

... A subtle possibility is that the SCM estimates have a compressed dynamic range relative to true values, which would inflate both the slope of the translational-activity–mRNA relationship and the correlation between TE ...

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MicroRNAs as a novel class of diagnostic biomarkers for the detection of osteosarcoma: a meta-analysis

MicroRNAs as a novel class of diagnostic biomarkers for the detection of osteosarcoma: a meta-analysis

... However, at this time, no agreement has been reached among several miRNA expression–profiling studies. Dif- ferent protocols, measurement platforms, and small sample sizes could result in incomparable ...

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Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response-Targeted Therapies in Breast Cancer.

Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response-Targeted Therapies in Breast Cancer.

... In addition, recent profiling studies have also identified CDK12 mutations in primary and castration resistant prostate cancer that are mutually exclusive with other muta[r] ...

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Profiling academic research on discourse studies and second language learning

Profiling academic research on discourse studies and second language learning

... research profiling studies, it is necessary to open the spectrum including in future studies other bibliographic databases to get a better profile ...

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MicroRNAs -the Next Generation Therapeutic Targets in Human Diseases

MicroRNAs -the Next Generation Therapeutic Targets in Human Diseases

... the studies focus on the derivatives of soluble-A and tau in Alzheimer’s disease[30, 31], but a few focus on blood and CSF and have reconnoitered the role of miRNA[32, ...the studies discussed about the ...

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Exosomal microRNAs as potential circulating biomarkers in gastrointestinal tract cancers: a systematic review protocol

Exosomal microRNAs as potential circulating biomarkers in gastrointestinal tract cancers: a systematic review protocol

... on studies that have evaluated circulating exosomal miR- NAs as non-invasive biomarkers in serum of patients with primary GI ...miRNAs, profiling studies that were performed by microarray and ...

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Pharmacoresistance in Epilepsy: An Integrative Genetic & Genomic Analysis

Pharmacoresistance in Epilepsy: An Integrative Genetic & Genomic Analysis

... expression profiling studies on brain tissue from epilepsy surgery; the largest and most robust microarray analysis of brain tissue from surgery for pharmacoresistant mesial temporal lobe epilepsy; and the ...

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Identification of Targets and Pathways Controlled by the Chicken MicroRNAs miR-10a and miR-143

Identification of Targets and Pathways Controlled by the Chicken MicroRNAs miR-10a and miR-143

... lymphocytic leukemia, and colorectal and cervical cancers (Michael et al. 2003; Akao et al. 2007; Lui et al. 2007; Slaby et al. 2007). Given the transforming potential of KLF5 in Ras- mutated colorectal cancers, ...

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Predicting treatment outcome in classical Hodgkin lymphoma: genomic advances

Predicting treatment outcome in classical Hodgkin lymphoma: genomic advances

... molecular profiling technologies, such as SNP arrays, comparative genomic hybridization, and gene-expression profiling, have allowed the identification of new prognostic factors that may be useful for risk ...

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Gestational tissue transcriptomics in term and preterm human pregnancies: a systematic review and meta-analysis

Gestational tissue transcriptomics in term and preterm human pregnancies: a systematic review and meta-analysis

... transcriptomic studies on placental tissue samples from women with preeclampsia dominate PTB ...few studies focus- ing on sPTB, a subtype responsible for 45 % of all PTB ...expression studies to be ...

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Profiling Families Enrolled in Food Allergy Immunotherapy Studies

Profiling Families Enrolled in Food Allergy Immunotherapy Studies

... search studies for food allergy report a similar impact of food allergy on their quality of life compared with par- ents of children not enrolled in immu- notherapy ...

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Peripheral chondrosarcoma progression is accompanied

Peripheral chondrosarcoma progression is accompanied

... expression profiling experiments of peripheral and central [28] cartilaginous tumours, with the least variation between all samples using the geNorm pro- gramme ...

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TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance

TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance

... TFEB may be a new target in AKI. Monogenic lysosomal diseases illustrate how important safe waste disposal is for human renal health (39). Termed the Coordinated Lysosomal Expression And Regulation network (CLEAR ...

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Examination of Cyber-criminal Behaviour

Examination of Cyber-criminal Behaviour

... place. Profiling has traditionally been thought of as attempting to reduce the number of possible offenders to the point where traditional methods of investigation can be introduced to solve the case (Ainsworth, ...

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Seaweeds as an alternative crop for the production of protein

Seaweeds as an alternative crop for the production of protein

... As PI protein yields for seaweeds (up to 48 %) are considerably lower than those that are routinely achieved for terrestrial seed crops (> 75 %) (Berk 1992; Ju et al. 2001), there is considerable scope to improve the ...

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Understanding the Metabolic and Genetic Regulation of Breast Cancer Recurrence Using Magnetic Resonance-Based Integrative Metabolomics

Understanding the Metabolic and Genetic Regulation of Breast Cancer Recurrence Using Magnetic Resonance-Based Integrative Metabolomics

... For the past few decades, the conventional magnetic resonance (MR) technique used to monitor total metabolite concentrations in vivo has consisted of Nuclear Magnetic Resonance (NMR) spectroscopy, a technique that ...

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Metabolite Profiling and Principle Component Analysis of a Mangrove Plant Aegiceras Corniculatum L (Blanco)

Metabolite Profiling and Principle Component Analysis of a Mangrove Plant Aegiceras Corniculatum L (Blanco)

... While Methyl-5,2 (undecylcyclopropyl) pentanote, 2,3- epoxy-2-methyl, cholestran [18], Carbostyril, 3-ethyl-4- hydroxy-7-methoxy [19], 2,2,4-trimethyl-3-Penten-1-ol [20] were reported to have good antimicrobial activity. ...

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Stone formation in peach fruit exhibits spatial coordination of the lignin and flavonoid pathways and similarity to Arabidopsisdehiscence

Stone formation in peach fruit exhibits spatial coordination of the lignin and flavonoid pathways and similarity to Arabidopsisdehiscence

... When placed in a physiological context, the expression patterns of lignin and flavoniod pathway genes are con- sistent with known aspects of peach fruit development. Peach fruit grow on a sigmoidal curve and show a ...

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