proline-rich region 2
Characterization of RNA Determinants Recognized by the Arginine- and Proline-Rich Region of Us11, a Herpes Simplex Virus Type 1-Encoded Double-Stranded RNA Binding Protein That Prevents PKR Activation
... segment rich in arginine and ...containing 2 ⴕ hydroxyl groups from those that do ...and proline-rich Us11 RNA binding domain is unrelated to known dsRNA binding elements and thus constitutes ...
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A Proline-Rich Region in the Coxsackievirus 3A Protein Is Required for the Protein To Inhibit Endoplasmic Reticulum-to-Golgi Transport
... Enterovirus genome replication takes place at secretory pathway-derived membrane vesicles that accumulate in the cytosol of the infected cell. The 2BC protein has been identi- fied as playing a major role in the ...
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PCR Assays for Identification of Coccidioides posadasii Based on the Nucleotide Sequence of the Antigen 2/Proline Rich Antigen
... Targeting a specific gene may decrease the sensitivity of diagnostic PCR assays in comparison to PCRs targeting mul- ticopy rRNA genes (18). However, primers within conserved gene regions can amplify DNA of nonpathogenic ...
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The Metastatic Suppressor Nm23-H1 Interacts with EBNA3C at Sequences Located between the Glutamine- and Proline-Rich Domains and Can Cooperate in Activation of Transcription
... binding region. The results of these assays indicate that the region of EBNA3C that inter- acts with Nm23-H1 lies between aa 629 and 792, which encom- passes the proline- and glutamine-rich ...
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A Proline-Rich N-Terminal Region of the Dengue Virus NS3 Is Crucial for Infectious Particle Production
... At 2 and 3 days posttrans- fection, supernatant fluids were recovered and store on ice, while trans- fected cells were suspended by trypsinization, washed once with PBS sup- plemented with 2% FBS, and then ...
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Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation
... lPs 2 µg/ml for 72 ...the proline-rich region of gilZ; lPs, lipopolysaccharide; gilZ-P c , noncovalent complex of Pep-1 with gilZ-P; MTT, 3-(4,5-dimethyl-thiazol-2-yl)-2,5 diphenyl ...
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Free Energy and Structural Characteristics of Proline-rich Peptides with Distributed Multiple Guests.
... the proline-rich peptides, these display similar characteristics as the comparable structures with isolated single- and multiple ...A proline which is followed by another proline has almost ...
55
The Novel Adaptor Protein, Mti1p, and Vrp1p, a Homolog of Wiskott-Aldrich Syndrome Protein-Interacting Protein (WIP), May Antagonistically Regulate Type I Myosins in Saccharomyces cerevisiae
... acidic region of Myo5p (Figure ...the region encompassing the YJL020C Myo3/5p-SH3-AD to a similar extent as Mti1p (665– and YJL021C sequences encodes a single protein, 1157) and Mti1p (799–1157); Mti1p ...
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The C-Terminal Proline-Rich Tail of Human Immunodeficiency Virus Type 2 Vpx Is Necessary for Nuclear Localization of the Viral Preintegration Complex in Nondividing Cells
... the proline-rich region of Vpx could be important for protein-protein ...bind proline-rich ligands through recognition of a PXXP motif ...bind proline-rich ligands in ...
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Acid sensing in renal epithelial cells
... the proline-rich tyrosine kinase 2 (Pyk2), a member of the focal adhesion kinase (FAK) family, acts as both a pH sensor and activator of ...perinuclear region, or the nucleus in response to ...
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Characterization of the Proline-Rich Region of Murine Leukemia Virus Envelope Protein
... Western blot analysis of envelope proteins in viral particles and cell lysates. Retroviral particles generated by transient transfection of 293T cells were pel- leted through 20% sucrose at 16,000 3 g and 4°C for 30 min. ...
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Alternatively spliced proline rich cassettes link WNK1 to aldosterone action
... only 2 such motifs contained within the entire WNK1 sequence and are tightly restricted to the same proline-rich region of the protein, within 2 neighboring exons that undergo extensive ...
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Cloning and Characterization of Cbl-associated Protein Splicing Isoforms
... additional proline-rich region with different length in these 2 ...A proline-rich region may represent SH3 or WW domain-binding motifs, which are often found in signaling ...
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Cytoskeletal signaling proteins : complex regulatory mechanisms and roles in innate immunity
... binding promotes FAK inactivation. However, fibroblasts expressing a SHP-2 mutant lacking phosphatase activity exhibits defects in cell spreading and cell migration. The detailed mechanism is still unclear (501). ...
226
Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues
... Integrin αvβ3 activation induces FAK and Pyk2 phosphoryla- tion via Src. Phosphorylation of FAK and Pyk2 results in forma- tion of a signaling complex consisting of signaling molecules including Src and paxillin. ...
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Heterologous expression of abaecin peptide from Apis mellifera in Pichia pastoris
... In order to the abaecin peptide be tested in E. coli sam- ples, the optimum incubation period was 24 h. After this time the OD of the analyzed samples decreases, suppos- edly because bacterial growth reaches a high ...
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Isolation and characterization of Bradykinin potentiating peptides from Agkistrodon bilineatus venom
... several proline residues in BPPs, has equipped these peptides with inherent resistance to ...(Table 2) illustrate that while peptides 5, 6 and 7 show low IC 50 values, peptide 3 has a much higher ...Table ...
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The effect of proline on the network structure of major ampullate silks as inferred from their mechanical and optical properties
... a proline-deficient network versus a proline-rich network on the properties of MA ...either proline-rich (+Pro) or proline-deficient (–Pro) ...the proline-rich ...
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Intrabodies as therapeutics for Huntington's disease
... anti-P- rich intrabodies suggests that this effect is a direct result of blocking these epitopes and therefore that this domain has a role in modulating stability of the mutant ...
219
The role of SH3BP2 in the pathophysiology of cherubism
... “Bone dystrophies paint queer and irregular pictures throughout the skeleton and have been reported in most bones ” W.A. Jones begins his 1950 review, where he pro- posed the name “ cherubism ” for the multilocular ...
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