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prostate cancer cells

Identification of a C-FABP-PPARγ-VEGF axis promoting tumorigenicity in prostate cancer cells

Identification of a C-FABP-PPARγ-VEGF axis promoting tumorigenicity in prostate cancer cells

... in prostate cancer, their expression status was assessed in prostate cell lines and ...benign cells and in BPH and it appeared that their expression levels were increased as the increasing ...

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Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cells

Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cells

... 145 prostate cancer cells treated with EP (25 and 50 μM) were washed with cold ...PBS. Cells were seeded after fixing with 4% paraformalde- hyde for 30 min and washed twice with PBS for 2 ...

8

Dihydroisotanshinone I combined with radiation inhibits the migration ability of prostate cancer cells through DNA damage and CCL2 pathway

Dihydroisotanshinone I combined with radiation inhibits the migration ability of prostate cancer cells through DNA damage and CCL2 pathway

... HEI-OC1 cells, a mouse auditory cell line ...of prostate cancer cells in a more effect- ive manner than did the larger dose of IR (10 ...in prostate cancer ...recruit ...

10

Original Article Silencing of CCR7 inhibits the growth, invasion and migration of prostate cancer cells induced by VEGFC

Original Article Silencing of CCR7 inhibits the growth, invasion and migration of prostate cancer cells induced by VEGFC

... in prostate cancer development, tumor cells express vascular endothelial growth factor C (VEGF-C), a secreted molecule that is important in angiogenesis ...human prostate cancer ...

8

Original Article miR-24-3p stimulates migration, invasion and proliferation of prostate cancer cells by targeting suppressor of cytokine signaling 6

Original Article miR-24-3p stimulates migration, invasion and proliferation of prostate cancer cells by targeting suppressor of cytokine signaling 6

... Abstract: Prostate cancer is among the most widespread malignancies affecting men in the ...in prostate cancer cells and the involvement of its regulating microRNA (miR), ...miR-24-3p. ...

8

MCM3AP-AS1/miR-876-5p/WNT5A axis regulates the proliferation of prostate cancer cells

MCM3AP-AS1/miR-876-5p/WNT5A axis regulates the proliferation of prostate cancer cells

... of prostate cancer cells through Notch signal- ing pathway ...PCa cells by disrupting methylation of the NPY1R pro- moter to inactivate the MAPK pathway ...and cells; it was found that ...

12

EVALUATION OF ANTICANCER PROPERTY OF GOSSYPOL USING HeLa CELL LINE

EVALUATION OF ANTICANCER PROPERTY OF GOSSYPOL USING HeLa CELL LINE

... Dunning prostate cancer cells (human prostate cancer cells derived from a bone marrow metastasis (PC3)), MCF-7 and primary cultured human prostate ...human prostate ...

10

Gene Expression Profile, Androgen Independence and Prostate Cancer

Gene Expression Profile, Androgen Independence and Prostate Cancer

... in prostate cancer cells earlier dependent on androgens us- ing LNCap cell and sublimes ...LNCap cells were fast growing, and had ability of potentiating the growth of endothelia cells, ...

8

Dickkopf 1 is regulated by the mevalonate pathway in breast cancer

Dickkopf 1 is regulated by the mevalonate pathway in breast cancer

... Breast cancer cells (MDA-MB-231, MCF-7 and T47D) and prostate cancer cells (PC-3 and MDA-PCa2b) were pur- chased from ATCC (Manassas, VA, USA), except for MDA-BONE cells (also ...

13

Original Article LKB1 suppresses proliferation and invasion of prostate cancer through hedgehog signaling pathway

Original Article LKB1 suppresses proliferation and invasion of prostate cancer through hedgehog signaling pathway

... in prostate cancer development remains largely ...human prostate cancer tissue samples and prostate cancer cell lines was detected, and the effects of LKB1 on prostate ...

9

Original Article NUAK1 knockdown suppresses prostate cancer cell epithelial-mesenchymal transition, migration, and invasion through microRNA-30b-5p

Original Article NUAK1 knockdown suppresses prostate cancer cell epithelial-mesenchymal transition, migration, and invasion through microRNA-30b-5p

... Objective: Prostate cancer is one of the most diagnosed malignancies in men ...in prostate tumorigenesis has not been fully ...in prostate cancer cell lines and ...in prostate ...

11

The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer

The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer

... all prostate cancer cells tested (Figure ...of prostate cancer cells into SCID mice were performed to determine if human prostate cancer cells could be ...

16

Androgen deprivation–induced NCoA2 promotes metastatic and castration resistant prostate cancer

Androgen deprivation–induced NCoA2 promotes metastatic and castration resistant prostate cancer

... advanced prostate cancer (PCa) in patients is the resistance of tumors to androgen deprivation therapy (ADT) and their subsequent development into castration-resistant prostate cancer ...the ...

15

Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function

Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function

... PC-3 cells compared to Dox-treated tdTom-expressing PC-3 cells (Figure 8); however, RNA immunoprecipitation studies must be performed to prove that TTP directly binds to and regulates these mRNAs in ...

14

Choline PET and PET/CT in Primary Diagnosis and Staging of Prostate Cancer

Choline PET and PET/CT in Primary Diagnosis and Staging of Prostate Cancer

... of prostate cancer cells and FDG uptake: low differenti- ated prostate cancer cells show higher FDG uptake in comparison to higher differentiated prostate cancer ...

13

Potential use of STAT3 inhibitors in targeted prostate cancer therapy: future prospects

Potential use of STAT3 inhibitors in targeted prostate cancer therapy: future prospects

... 2012, prostate cancer will once again be the second-leading cause of cancer death of American ...treatable, prostate cancer can recur in a hormone refrac- tory form that is not ...

7

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer

... metastatic prostate cancer ...metastatic prostate cancer samples (n = ...from prostate cancers expressing high and low levels of ...the prostate cancer samples collected ...

17

USP35 activated by miR let-7a inhibits cell proliferation and NF-κB activation through stabilization of ABIN-2

USP35 activated by miR let-7a inhibits cell proliferation and NF-κB activation through stabilization of ABIN-2

... PC3 prostate cancer cells than that in non-malignant prostate epithelial cells ...breast cancer cells as well as in H1299 and A549 lung cancer cells compared ...

16

SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression

SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression

... We next evaluated whether other subunits of the SPOP-CUL3-RBX1 E3 ubiquitin ligase complex are also required for ATF2 degradation. We depleted RBX1 or CUL3 by two gene-specific shRNAs and examined the changes in ATF2 ...

13

The role of QRFP & GPR103 in human prostate cancer

The role of QRFP & GPR103 in human prostate cancer

... of cells (Robertson et ...DU145 cells and poor ...in prostate cancer is involved in cell proliferation, cell survival and poorly differentiated metastatic, however recently has been shown ...

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