Protein Conserved Domain Identification & Modelling
Systematic identification of conserved bacterial c-di-AMP receptor proteins.
... pDEST17 protein expres- sion vector, placing each ORF under the control of the IPTG- inducible T7 ...coli protein expression strain ...Next, protein expression was induced and whole cell ...visible ...
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Identification of Multiple Protective Epitopes (Protectopes) in the Central Conserved Domain of a Prototype Human Respiratory Syncytial Virus G Protein
... central conserved region compared with RSV-A- infected or immunized ...the conserved epitope usage in ...central conserved region of the RSV G protein may constitute an important component of ...
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Using context to improve protein domain identification
... exploit domain co-occurrence to boost weak domain predictions that appear in previously observed combinations, while penalizing higher confidence domains if such combinations have never been ...framework, ...
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Identification of a nuclear export signal in the catalytic subunit of AMP-activated protein kinase
... Brenman) AMP-activated protein kinase (AMPK) is an energy sensor that regulates both cellular and organismal energy levels through phosphorylation, leading to the activation or inhibition of target ...are ...
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The RNA Binding Domain of the Hantaan Virus N Protein Maps to a Central, Conserved Region
... Identification of common features of RBDs among the hanta- viral nucleocapsid proteins may require elucidation of their three-dimensional structures. To confirm the contribution of amino acids or the effect of the ...
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Neverland is an evolutionally conserved Rieske domain protein that is essential for ecdysone synthesis and insect growth
... facilitate identification and characterization of components responsible for ecdysteroid biosynthesis, we have used Bombyx to identify genes predominantly expressed in the PG (Niwa et ...evolutionally ...
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Identification of a membrane fusion domain and an oligomerization domain in the baculovirus GP64 envelope fusion protein.
... particular conserved residues in the SFV or VSV fusion domains abolished fusion activity with- out affecting transport to the cell surface, whereas substitutions of other conserved residues altered the pH ...
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Identification of a Dynein Interacting Domain in the Papillomavirus Minor Capsid Protein L2
... bule-associated protein. A consensus sequence, R/KR/ KXXR/K, for binding to Tctex-1, a light chain of cytoplasmic dynein, was recently identified in various functionally unre- lated Tctex-1 target proteins (17). ...
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Identification and characterization of Coronaviridae genomes from Vietnamese bats and rats based on conserved protein domains
... We describe a Coronaviridae sequence classification strategy based on the set of protein domains encoded by the genome se- quence. The classification is not dependent on a single domain, but rather the ...
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Integrating domain similarity to improve protein complexes identification in TAP-MS data
... identify protein com- ...Local Modelling algorithm [15] to this directed network to search for dense sub-networks in which all pairs of proteins should be ...Local Modelling algorithm mapped well to ...
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CDD: a Conserved Domain Database for protein classification
... subdividing domain super- families: a large number of domain models will affect the database search time, and experimentally backed functional annotation is sparse in many ...ancient conserved ...
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Protein subfamily assignment using the Conserved Domain Database
... of protein domain families make it possi- ble to quickly classify more distant homologs [23] and can better handle multi-domain ...known protein fam- ilies is identifying the subclass that ...
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Conserved phosphorylation hotspots in eukaryotic protein domain families
... regulate protein functions within seconds to minutes time ...of protein post-translational modifications (PTMs) are known, ranging from single atom modifications (oxide) to small protein modifiers ...
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A Conserved Domain in the Coronavirus Membrane Protein Tail Is Important for Virus Assembly
... Our results strongly suggest that the N protein helps stabi- lize envelope assembly complexes during VLP assembly, most likely through interactions with M. We have some understand- ing about the role that N plays ...
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Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein.
... To address the role of the conserved basic domain of the tat protein in the trans-activation of HIV-1 LTR-specific gene expression, we used oligonucleotide- directed mutagenesis (35) to [r] ...
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Protein Domain Identification Curso Doctorado UAM 2008
... Sequence Sequence DataBases GenBank dbEST Domain Databases ALIGNMENT DOMAIN Functional Hypothesis HMMer Biochemical Knowledge Hypothetical Domain Domain Oriented Seque[r] ...
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Modelling and identification of non-linear deterministic systems in the delta-domain
... There is an exact relationship between the polynomial δ- and q-domain NARX models, which is shown in sec- tion 3. This theoretical equivalence, which does not nec- essarily exist for all classes of non-linear ...
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Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx
... a conserved, membrane-proximal ...this domain, but includes the adjacent transmembrane helices (Figure ...a conserved proline and two conserved glycine residues in the transmembrane ...the ...
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Coordinate expression of ribqsomal protein genes in Neurospora crassa and identification of conserved upstream sequences
... The preliminary sequence of a crp-4 cDNA clone encodes an amino acid sequence with 68% identity to that of yeast YL3 (de la Serna, Shi and Tyler, unpublished; J. Woolford, personal commu[r] ...
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Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1
... UIM domain of Rpn10 [54,55], and that even yeast Rad23 can bind Rpn10 [18] but it should be noted that this hypothesis has not been tested by genetic manipulation of Rpn10 in ...
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